ChemicalBook > CAS DataBase List > 4'-AMINOPROPIOPHENONE

4'-AMINOPROPIOPHENONE

Product Name
4'-AMINOPROPIOPHENONE
CAS No.
70-69-9
Chemical Name
4'-AMINOPROPIOPHENONE
Synonyms
NSC 3187;NSC 404994;usafuctl-1856;USAF uctl-1856;4-aminopropanone;4'AMINOPROPIOPHENE;4-Propanoylaniline;4-Propionylaniline;P-AMINOPROPIOPHENONE;4-AMINOPROPIOPHENONE
CBNumber
CB4460800
Molecular Formula
C9H11NO
Formula Weight
149.19
MOL File
70-69-9.mol
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4'-AMINOPROPIOPHENONE Property

Melting point:
135-140 °C
Boiling point:
270.27°C (rough estimate)
Density 
1.067±0.06 g/cm3 (20 ºC 760 Torr)
refractive index 
1.5279 (estimate)
storage temp. 
Sealed in dry,Room Temperature
form 
solid
pka
2.86±0.10(Predicted)
color 
Needles from water
Water Solubility 
352.1mg/L(37.5 ºC)
CAS DataBase Reference
70-69-9(CAS DataBase Reference)
EPA Substance Registry System
p-Aminopropiophenone (70-69-9)
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Safety

Hazard Codes 
T
Risk Statements 
25
Safety Statements 
45-28A
RIDADR 
2811
HazardClass 
6.1(b)
PackingGroup 
III
HS Code 
29223990
Hazardous Substances Data
70-69-9(Hazardous Substances Data)
Toxicity
LD50 in male, female mice (mg/kg): 145, 200 i.v.; in female mice, guinea pigs, rats, male rats (mg/kg): >5000, 1020, 223.7, 475 orally (Scawin)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

Precautionary statements

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

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N-Bromosuccinimide Price

AK Scientific
Product number
X6226
Product name
4'-Aminopropiophenone
Packaging
250mg
Price
$26
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA70236
Product name
4'-Aminopropiophenone
Packaging
1g
Price
$50
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA70236
Product name
4'-Aminopropiophenone
Packaging
2g
Price
$90
Updated
2021/12/16
Activate Scientific
Product number
AS145342
Product name
1-[4-(Dimethylamino)-2-hydroxyphenyl]ethan-1-one
Purity
95%
Packaging
250mg
Price
$134
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA70236
Product name
4'-Aminopropiophenone
Packaging
5G
Price
$150
Updated
2021/12/16
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4'-AMINOPROPIOPHENONE Chemical Properties,Usage,Production

Description

4'-Aminopropiophenone is an oxygen-carrying molecule that has been shown to have genotoxic effects. It can be used as a control agent in toxicity studies. 4'-Aminopropiophenone also has locomotor activity in animals and affects the function of neurons. This compound has not yet been tested on humans, but it is suspected that it may have a similar effect on the human body. The analytical method for this compound is based on the spectrophotometric measurement of amines. The test for this compound is done by injecting a dose into an animal and measuring the concentration of creatinine sulfate in its blood sample over time with a spectrophotometer. Radiation can alter the shape of the molecules and change their color, so it must be kept away from this chemical during testing.

Chemical Properties

yellow-brown crystalline powder, scales

Uses

4''-Aminopropiophenone is used in method for preparing high-strength carbon nanotube film by thiol-ene click reaction.

Preparation

The preparation of 4'-aminopropiophenone is as follows:A reaction tube was charged with the 2-aryloxypropanamide (1.0 mmol), potassium hydroxide (56 mg, 1.0 mmol) and DMSO (4 mL). The mixture was heated at 140 C for 3-8 h. The reaction was monitored by TLC. After the reaction period, the reaction mixture was cooled, diluted with saturated brine and extracted with dichloromethane three times. The combined organic layers were washed with three portions of saturated brine and then dried over MgSO4 and filtered. Solvent was removed under reduced pressure. The product was purified through flash column chromatography on 300-400 mesh silica gel with petroleum ether/ethyl acetate as eluent.

General Description

Yellow needles.

Reactivity Profile

4'-AMINOPROPIOPHENONE is simultaneously a ketone and an amine. Neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen may be generated in combination with strong reducing agents, such as hydrides.

Safety Profile

Poison by ingestion and intraperitoneal routes. Ingestion of large doses can cause cyanosis. A flammable liquid. When heated to decomposition it emits toxic fumes of NOx,.

Purification Methods

Crystallise it from water or aqueous EtOH. The hydrochloride has m 188-189o (aqueous EtOH/HCl drops), and the semicarbazone has m 139-140o (from EtOH/H2O). [Derrick & Bornemann J Am chem. Soc 35 1283 1913, Beilstein 14 H 59, 14 I 375, 14 III 146, 14 IV 139.]

4'-AMINOPROPIOPHENONE Preparation Products And Raw materials

Raw materials

Preparation Products

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4'-AMINOPROPIOPHENONE Suppliers

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View Lastest Price from 4'-AMINOPROPIOPHENONE manufacturers

Changzhou waston chemical technology Co.,Ltd
Product
4'-AMINOPROPIOPHENONE 70-69-9
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
According to customer requirements
Release date
2022-10-11
Career Henan Chemical Co
Product
4'-AMINOPROPIOPHENONE 70-69-9
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100kg
Release date
2019-07-12

70-69-9, 4'-AMINOPROPIOPHENONERelated Search:


  • P-AMINOPROPIOPHENONE
  • P-AMINOPHENYL ETHYL KETONE
  • NSC 3187
  • NSC 404994
  • 4'-Aminopropiophenone,98%
  • 4'-Aminopropiophenone1-(4-Aminophenyl)-1-propanone
  • 4'-Aminopropiophenone hydrochloride salt
  • 1-(4-aminophenyl)-1-propanon
  • 4’-amino-propiophenon
  • Para-aminopropiophenone
  • paraminopropiophenone
  • Propiophenone, 4'-amino-
  • USAF uctl-1856
  • usafuctl-1856
  • 1-(4-AMINOPHENYL)-1-PROPANONE
  • 4'-AMINOPROPIOPHENONE
  • 4-AMINOPROPIOPHENONE
  • Ethyl-p-aminophenyl ketone
  • 1-Propanone, 1-(4-aminophenyl)-
  • 4'AMINOPROPIOPHENE
  • p-aminopropio-phenone,PAPP
  • 4''-AMINOPROPIOPHENONE 96+%
  • Aminopropiophenone, 4-
  • 4-Propanoylaniline
  • 4-Propionylaniline
  • 4'-Aminopropiophenonec
  • 1-(4-(dimethylamino)-2-hydroxyphenyl)ethan-1-one
  • 4'-AMINOPROPIOPHENONE
  • 4'-Aminopropiophenonec
  • 4-aminopropanone
  • 70-69-9
  • Aromatic Propiophenones (substituted)