ChemicalBook > CAS DataBase List > LOXO-292
LOXO-292
Uses- Product Name
- LOXO-292
- CAS No.
- 2222755-14-6
- Chemical Name
- LOXO-292
- Synonyms
- RET-IN-1;RET IN 1,RETIN1;selpercatinib(LOX0292);Pyrazolo[1,5-a]pyridine-3-carbonitrile, 4-[5-[6-[(6-methoxy-3-pyridinyl)methyl]-3,6-diazabicyclo[3.1.1]hept-3-yl]-2-pyrazinyl]-6-[(2R)-2-morpholinylmethoxy]-
- CBNumber
- CB44668147
- Molecular Formula
- C29H31N9O3
- Formula Weight
- 553.61
- MOL File
- 2222755-14-6.mol
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LOXO-292 Property
- Density
- 1.49±0.1 g/cm3(Predicted)
- storage temp.
- Dry, dark and at 0 - 4℃ for short term (days to weeks) or -20℃ for long term (months to years).
- solubility
- Soluble in DMSO
- pka
- 8.23±0.40(Predicted)
- form
- solid
- InChIKey
- GTQISTQEBXXLPC-UBVWURDFSA-N
- SMILES
- C12=C(C#N)C=NN1C=C(OC[C@@H]1OCCNC1)C=C2C1=NC=C(N2CC3CC(N3CC3=CC=C(OC)N=C3)C2)N=C1
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N-Bromosuccinimide Price
American Custom Chemicals Corporation
- Product number
- KIN0008603
- Product name
- LOXO-292
- Purity
- 95.00%
- Packaging
- 5MG
- Price
- $454.89
- Updated
- 2021/12/16
DC Chemicals
- Product number
- DC24201
- Product name
- RET-IN-1
- Purity
- >98%
- Packaging
- 250mg
- Price
- $3500
- Updated
- 2021/12/16
DC Chemicals
- Product number
- DC24201
- Product name
- RET-IN-1
- Purity
- >98%
- Packaging
- 1g
- Price
- $6500
- Updated
- 2021/12/16
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LOXO-292 Chemical Properties,Usage,Production
Uses
Serpatinib (LOXO-292) is a potent, orally administered, highly selective transfection rearrangement (RET) kinase inhibitor used to treat cancer patients with RET abnormalities. The RET gene is a proto-oncogene that undergoes rearrangement during transfection, hence its name. This gene encodes a cell membrane receptor tyrosine kinase, and its abnormalities are a rare driver of many types of tumors.
Description
RET-IN-1 is an oral and selective investigational drug in clinical development for the treatment of patients with cancers that harbor abnormalities in the rearranged during transfection (RET) kinase.
LOXO-292 Preparation Products And Raw materials
Raw materials
Preparation Products
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LOXO-292 Suppliers
- Tel
- 13467605171
- Fax
- 0731-83285201
- 2580432242@qq.com
- Country
- China
- ProdList
- 184
- Advantage
- 58
- Tel
- +21-18501659228 18501659228
- Fax
- sales@hope-chem.com
- info@hope-chem.com
- Country
- China
- ProdList
- 474
- Advantage
- 55
- Tel
- 010-56645598 13366904824
- Fax
- 01062230033
- bjkaida@163.com
- Country
- China
- ProdList
- 1618
- Advantage
- 59
- Tel
- +86-2332782371 +86-18120098618
- sales@adobechem.com
- Country
- China
- ProdList
- 1250
- Advantage
- 50
- Tel
- 021-58088081 Q2635253576
- Fax
- QQ3382968513
- hailey@shsendpharm.com
- Country
- China
- ProdList
- 2081
- Advantage
- 55
- Tel
- 021-021-58111628 15800915896
- Fax
- QQ 3285589261
- sales@twochem.com
- Country
- China
- ProdList
- 304
- Advantage
- 55
- Tel
- 028-86040038 13980902949;
- Fax
- 028-85149890
- market@dingdangchem.com
- Country
- China
- ProdList
- 1853
- Advantage
- 55
- Tel
- +86-0531-88801869 15090917080
- Fax
- 0531-88801867
- sciencechem@163.com
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- China
- ProdList
- 283
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- 55
- Tel
- 0317-5296180 15533709196
- Fax
- 0317-5106596
- sale@enkepharma.com
- Country
- China
- ProdList
- 2267
- Advantage
- 55
- Tel
- 021-QQ：65489617 15618227136
- Fax
- 21-5161 9052
- Sales@ATKchemical.com
- Country
- China
- ProdList
- 9125
- Advantage
- 58
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View Lastest Price from LOXO-292 manufacturers
Zibo Hangyu Biotechnology Development Co., Ltd
- Product
- LOXO-292 2222755-14-6
- Price
- US $90.00-900.00/kg
- Min. Order
- 10kg
- Purity
- 0.99
- Supply Ability
- 20tons
- Release date
- 2023-10-30
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