ZL0454

Product Name: ZL0454
CAS No.: 2229042-77-5
Chemical Name: ZL0454
Synonyms: ZL0454;ZL0454,ZL-0454;Benzenesulfonamide, 4-[(1E)-2-(2-amino-4-hydroxy-5-methylphenyl)diazenyl]-N-cyclopentyl-
CBNumber: CB44668703
Molecular Formula: C18H22N4O3S
Formula Weight: 374.46
MOL File: 2229042-77-5.mol

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ZL0454 Property

Boiling point:: 630.6±65.0 °C(Predicted)
Density: 1.41±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: DMSO : 50 mg/mL (133.53 mM; Need ultrasonic)
pka: 9.30±0.36(Predicted)
form: Solid
color: Brown to reddish brown

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Hazard and Precautionary Statements (GHS)

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ZL0454 Chemical Properties,Usage,Production

Biological Activity

ZL0454 is a potent and selective Bromodomain-containing protein 4 (BRD4) inhibitor with an IC50 of 49 and 32 nM for BD1 and BD2.

References

[1]. Liu Z, et al. Discovery of potent and selective BRD4 inhibitors capable of blocking TLR3-induced acute airway inflammation. Eur J Med Chem. 2018 May 10;151:450-461.

ZL0454 Preparation Products And Raw materials

Raw materials

Preparation Products

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ZL0454 Suppliers

China 7 United States 3 Global 10

TargetMol Chemicals Inc.

Tel: +1-781-999-5354 +1-00000000000
Email: marketing@targetmol.com
Country: United States
ProdList: 32161
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InvivoChem

Tel: +1-708-310-1919 +1-13798911105
Fax: 708-557-7486
Email: sales@invivochem.cn
Country: United States
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TargetMol Chemicals Inc.

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Email: support@targetmol.com
Country: United States
ProdList: 38631
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2229042-77-5, ZL0454Related Search:

ZLN005 4-((3,5-Dichloro-2-hydroxybenzyl)amino)-2-hydroxybenzoic acid ZL0420

ZL0454

ZL0454,ZL-0454

Benzenesulfonamide, 4-[(1E)-2-(2-amino-4-hydroxy-5-methylphenyl)diazenyl]-N-cyclopentyl-

2229042-77-5