N6-CYCLOHEXYLADENOSINE

Product Name: N6-CYCLOHEXYLADENOSINE
CAS No.: 36396-99-3
Chemical Name: N6-CYCLOHEXYLADENOSINE
Synonyms: CHA;Cyclohexyladenosine;N-Cyclohexyladenosine;N6-CYCLOHEXYLADENOSINE;Adenosine, N-cyclohexyl-;N6-Cyclohexyladenosine,CHA;N(sup 6)-cyclohexyladenosine;(2R,4S)-4-fluoropyrrolidine-6-carboxylicacid;N6-CYCLOHEXYLADENOSINE (CHA) SELECTIVE A 1 ADENOSIN;(2R,3R,4S,5R)-2-(6-(CyclohexylaMino)-9H-purin-9-yl)-5-(hydroxyMethyl)tetrahydrofuran-3,4-diol
CBNumber: CB4468462
Molecular Formula: C16H23N5O4
Formula Weight: 349.38
MOL File: 36396-99-3.mol

More

Less

N6-CYCLOHEXYLADENOSINE Property

Melting point:: 182 - 184°C
Boiling point:: 675.2±65.0 °C(Predicted)
Density: 1.71±0.1 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: DMSO (Slightly), Ethanol (Slightly), Methanol (Slightly)
form: Solid
pka: 13.12±0.70(Predicted)
color: White to Off-White
Stability:: Hygroscopic

More

Less

Safety

WGK Germany: 3
HS Code: 29349990

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

Cayman Chemical

Product number: 28427
Product name: N6-Cyclohexyladenosine
Packaging: 50mg
Price: $96
Updated: 2024/03/01

Cayman Chemical

Product number: 28427
Product name: N6-Cyclohexyladenosine
Packaging: 100mg
Price: $180
Updated: 2024/03/01

Cayman Chemical

Product number: 28427
Product name: N6-Cyclohexyladenosine
Packaging: 25mg
Price: $62
Updated: 2024/03/01

Tocris

Product number: 6863
Product name: N6-Cyclohexyladenosine
Purity: ≥98%(HPLC)
Packaging: 50
Price: $85
Updated: 2021/12/16

TRC

Product number: C989785
Product name: N6-Cyclohexyladenosine
Packaging: 500mg
Price: $745
Updated: 2021/12/16

More

Less

N6-CYCLOHEXYLADENOSINE Chemical Properties,Usage,Production

Description

N⁶-Cyclohexyladenosine is an adenosine receptor agonist. It selectively binds to adenosine A₁ receptors in rat cortical membranes (IC₅₀ = 2.3 nM) over A₂ receptors in rat striatal membranes (IC₅₀ = 870 nM). N⁶-Cyclohexyladenosine decreases heart rate and increases coronary flow in a perfused working rat heart model ex vivo (EC₂₅s = 5 and 860 nM, respectively). In vivo, it decreases heart rate and blood pressure in normotensive rats (EC₂₅s = 2.4 and 4.2 μg/kg, respectively). N⁶-Cyclohexyladenosine (100 μM) induces sleep in rats when administered via basal forebrain infusion. N⁶-Cyclohexyladenosine also decreases locomotor activity in mice (ED₅₀ = 60 μg/kg, i.p.).

Uses

N6-Cyclohexyladenosine is a derivative of Adenosine (A280400), and is used testing adenosine A1 and A2A receptor activation for pharmaceuticals such as antidepressants. N6-Cyclohexyladenosine also is used as a JAK2 inhibitor, blocking STAT3 signalling in human cancer cells.

Biochem/physiol Actions

Selective A1 adenosine receptor agonist.

storage

Store at -20°C

N6-CYCLOHEXYLADENOSINE Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

N6-CYCLOHEXYLADENOSINE Suppliers

China 40 Germany 1 India 1 Russia 1 Switzerland 1 United Kingdom 1 United States 11 Global 56

Nanjing Chemlin Chemical Co., Ltd

Tel: 025-83697070
Fax: +86-25-83453306
Email: info@chemlin.com.cn
Country: China
ProdList: 19182
Advantage: 64

Hangzhou Sage Chemical Co., Ltd.

Tel: +86057186818502 13588463833
Fax: Pls mail us for more information!
Email: info@sagechem.com
Country: China
ProdList: 10266
Advantage: 58

Chengdu NoVi Biotechnology Co., Ltd.

Tel: 028-81458053
Fax: 028-81458053
Email: novibiotech@163.com sales@novi-biotech.com
Country: China
ProdList: 226
Advantage: 55

Haoyuan Chemexpress Co., Ltd.

Tel: 021-58950125
Fax: (86) 21-58955996
Email: info@chemexpress.com
Country: China
ProdList: 7552
Advantage: 61

Nanjing Baifuli Technology Co., Ltd.

Tel: 25-25-58740604 15951658055
Fax: +86-25-58356858
Email: sales@unisyn.cn
Country: China
ProdList: 563
Advantage: 58

MedChemexpress LLC

Tel: 021-58955995
Fax: 609-228-5909
Email: sales@medchemexpress.cn
Country: United States
ProdList: 4861
Advantage: 58

Sigma-Aldrich

Tel: 021-61415566 800-8193336
Email: orderCN@merckgroup.com
Country: China
ProdList: 51456
Advantage: 80

DebyeTec.com Inc.

Tel: 18086626237 18086626237
Fax: qq:2693528373
Email: sales@debyesci.com
Country: China
ProdList: 2645
Advantage: 56

Zhengzhou Alfachem Co., Ltd.

Tel: 0371-53765687 18937137882
Fax: QQ:2885373884
Email: 2853979813@qq.com
Country: China
ProdList: 7979
Advantage: 55

ATK CHEMICAL COMPANY LIMITED

Tel: 021-51619050 13301662590
Fax: +86-21-51619052
Email: mandy@atkchemical.com
Country: China
ProdList: 10199
Advantage: 55

36396-99-3, N6-CYCLOHEXYLADENOSINERelated Search:

Tetramethylthiuram Disulfide Vulcanization accelerator 2',3'-dideoxy-N(6)-cyclohexyladenosine ferritin-cyclohexyladenosine N-ALLYL-N-CYCLOHEXYLADENOSINE N(6)-allyl-N(6)-cyclohexyladenosine (2S)-N6-[2-ENDO-NORBORNYL]ADENOSINE N6-METHYL-2'-DEOXY-ADENOSINE SDZWAG994 CYCLOHEXYLADENOSINE, N6-[ADENINE-2,8-3H]-,N 6-CYCLOHEXYLADENOSINE-[2,8-3H] 6-(METHYLAMINO)PURINE 6-METHYLAMINOPURINE 9-RIBOFURANOSIDE 6-N-HEXYLAMINOPURINE N6-CYCLOHEXYLADENOSINE

CHA

N6-CYCLOHEXYLADENOSINE

N6-CYCLOHEXYLADENOSINE (CHA) SELECTIVE A 1 ADENOSIN

N(sup 6)-cyclohexyladenosine

Cyclohexyladenosine

N-Cyclohexyladenosine

Adenosine, N-cyclohexyl-

N6-Cyclohexyladenosine,CHA

(2R,3R,4S,5R)-2-(6-(CyclohexylaMino)-9H-purin-9-yl)-5-(hydroxyMethyl)tetrahydrofuran-3,4-diol

(2R,4S)-4-fluoropyrrolidine-6-carboxylicacid

N-6-Cyclohexyladenosine,inhibit,Inhibitor,N6Cyclohexyladenosine,Adenosine Receptor,N6-Cyclohexyladenosine,N6 Cyclohexyladenosine,P1 receptor

36396-99-3