4-(1H-PYRROL-1-YL)ANILINE
- Product Name
- 4-(1H-PYRROL-1-YL)ANILINE
- CAS No.
- 52768-17-9
- Chemical Name
- 4-(1H-PYRROL-1-YL)ANILINE
- Synonyms
- ASISCHEM A93505;BUTTPARK 98\12-84;4-Pyrrol-1-yl-aniline;4-(1-Pyrrolyl)aniline;1-(4-AMINOPHENYL)PYRROLE;4-(1H-PYRROL-1-YL)ANILINE;4-Pyrrol-1-yl-phenylamine;Benzenamine, 4-(1H-pyrrol-1-yl)-
- CBNumber
- CB4476638
- Molecular Formula
- C10H10N2
- Formula Weight
- 158.2
- MOL File
- 52768-17-9.mol
4-(1H-PYRROL-1-YL)ANILINE Property
- Melting point:
- 81 °C
- Boiling point:
- 307.8±25.0 °C(Predicted)
- Density
- 1.09±0.1 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- pka
- 3.36±0.10(Predicted)
- Appearance
- Off-white to light yellow Solid
Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 26-36/37/39
- HazardClass
- IRRITANT
- HS Code
- 2933998090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H332Harmful if inhaled
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- P998810
- Product name
- 4-(1H-Pyrrol-1-yl)aniline
- Packaging
- 10mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- OR29302
- Product name
- 4-(1H-Pyrrol-1-yl)aniline
- Packaging
- 500mg
- Price
- $25
- Updated
- 2021/12/16
- Product number
- 3H30-1-F6
- Product name
- 4-(1H-Pyrrol-1-yl)aniline
- Packaging
- 500mg
- Price
- $28
- Updated
- 2021/12/16
- Product number
- OR29302
- Product name
- 4-(1H-Pyrrol-1-yl)aniline
- Packaging
- 1g
- Price
- $35
- Updated
- 2021/12/16
- Product number
- 3H30-1-F6
- Product name
- 4-(1H-Pyrrol-1-yl)aniline
- Packaging
- 1g
- Price
- $39
- Updated
- 2021/12/16
4-(1H-PYRROL-1-YL)ANILINE Chemical Properties,Usage,Production
Synthesis
4533-42-0
52768-17-9
Under standard reaction conditions, 5.0 mg of Pd-gCN catalyst (containing 5.0 wt% Pd) was added to an ethanol solution (2 mL) containing 1.0 mM 1-(4-nitrophenyl)-1H-pyrrole, followed by the addition of 2 mM (1.2 eq., 0.07 mL) of 60% hydrazine hydrate solution. The reaction mixture was transferred to a 10 mL round bottom flask and reacted at reflux temperature (70 °C) for 4 hours. After completion of the reaction, the mixture was cooled to room temperature and the catalyst was isolated by filtration. The filtrate was purified by silica gel column chromatography to give 4-(1-pyrrolyl)aniline. For dinitroaromatic substrates, 4.0 mM (2.4 eq., 0.14 mL) of 60% hydrazine hydrate solution is required.
References
[1] Applied Catalysis A: General, 2016, vol. 523, p. 31 - 38
[2] European Journal of Medicinal Chemistry, 2015, vol. 96, p. 369 - 380
[3] Zeitschrift fur Naturforschung - Section B Journal of Chemical Sciences, 1996, vol. 51, # 6, p. 757 - 764
[4] Recueil des Travaux Chimiques des Pays-Bas, 1943, vol. 62, p. 177,181, 183
[5] Farmaco, Edizione Scientifica, 1983, vol. 38, # 4, p. 219 - 231
4-(1H-PYRROL-1-YL)ANILINE Preparation Products And Raw materials
Raw materials
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