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4-Acetoxyindole

Product Name
4-Acetoxyindole
CAS No.
5585-96-6
Chemical Name
4-Acetoxyindole
Synonyms
1H-indol-4-yl acetate;2-(1H-indol-4-yl)acetate;Acetic acid 1H-indol-4-yl ester;ACETOXYINDOLE;4-ACETOXYINDOLE;4-INDOLYL ACETATE;4-INDOXYL ACETATE;4-acacetoxyindole;4-Acetoxyindole 98%;4-Acetoxy-1H-indole
CBNumber
CB4477655
Molecular Formula
C10H9NO2
Formula Weight
175.18
MOL File
5585-96-6.mol
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4-Acetoxyindole Property

Melting point:
100-102°C
Boiling point:
339.1±15.0 °C(Predicted)
Density 
1?+-.0.06 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
form 
Solid
pka
16.38±0.30(Predicted)
color 
Off-White to Beige
InChI
InChI=1S/C10H9NO2/c1-7(12)13-10-4-2-3-9-8(10)5-6-11-9/h2-6,11H,1H3
InChIKey
ZXDMUHFTJWEDEF-UHFFFAOYSA-N
SMILES
N1C2=C(C(OC(=O)C)=CC=C2)C=C1
CAS DataBase Reference
5585-96-6(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
WGK Germany 
3
Hazard Note 
Irritant
HS Code 
2933998090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H332Harmful if inhaled

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P310Immediately call a POISON CENTER or doctor/physician.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
259047
Product name
4-Indolyl acetate
Purity
99%
Packaging
250mg
Price
$51.24
Updated
2024/03/01
TRC
Product number
A165853
Product name
4-Acetoxyindole
Packaging
100mg
Price
$60
Updated
2021/12/16
TRC
Product number
A165853
Product name
4-Acetoxyindole
Packaging
500mg
Price
$75
Updated
2021/12/16
SynQuest Laboratories
Product number
4H23-1-0H
Product name
4-Acetoxyindole
Purity
98%
Packaging
5G
Price
$80
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA03468
Product name
4-Acetoxyindole
Packaging
2g
Price
$100
Updated
2021/12/16
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4-Acetoxyindole Chemical Properties,Usage,Production

Description

4-acetoxylindole is also known as 4-Indolyl acetate. It can be used as standards of the reverse phase HPLC during separation of small molecules. It can also be used as reactant during the preparation of inhibitors of HIV-attachment, prostanoid EP3 antagonist, indolyl-nitroalkanes and psilocybin.

Uses

Reactant for preparation of:• ;Inhibitors of HIV-1 attachment1• ;Prostanoid EP3 receptor antagonist, as a novel antiplatelet agent2• ;Indolyl-nitroalkanes via N-bromosuccinimide catalyzed synthesis3• ;Psilocybin as a medicinal agent4

Uses

Reactant for preparation of:

  • Inhibitors of HIV-1 attachment
  • Prostanoid EP3 receptor antagonist, as a novel antiplatelet agent
  • Indolyl-nitroalkanes via N-bromosuccinimide catalyzed synthesis
  • Psilocybin as a medicinal agent

Uses

4-Acetoxyindole is a useful intermediate for organic synthesis of Psilocine and Psilocine analogs.

General Description

4-Acetoxyindole is a chromophore that belongs to the pyrrole family of compounds. It has been shown to react with an ionic liquid under acidic conditions to form a protonated intermediate, which can be deprotonated by a nucleophile. This reaction yields an acetate anion and a fluorescing product. 4-Acetoxyindole also reacts with deuterium gas, yielding an acetate, a deuterium atom, and fluorescing product. The reaction is reversible and the yield of the product depends on the concentration of the reactants. 4-Acetoxyindole has strong carbonyl groups that make it reactive towards other functional groups. These reactions are useful for synthesizing heterocycles such as indoles and isoquinolines.

References

http://www.sigmaaldrich.com/catalog/product/aldrich/259047?lang=en&region=US
https://pubchem.ncbi.nlm.nih.gov/compound/4-Acetoxyindole

4-Acetoxyindole Preparation Products And Raw materials

Raw materials

Preparation Products

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4-Acetoxyindole Suppliers

BIOSYNTH AG
Tel
--
Fax
--
Email
welcome@biosynth.ch
Country
Switzerland
ProdList
1308
Advantage
60
SIGMA-RBI
Tel
--
Fax
--
Country
Switzerland
ProdList
6896
Advantage
91
Biosynth AG
Tel
--
Fax
--
Email
welcome@biosynth.ch
Country
Switzerland
ProdList
3324
Advantage
72
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View Lastest Price from 4-Acetoxyindole manufacturers

Hebei Ganmiao New material Technology Co., LTD
Product
4-Acetoxyindole 5585-96-6
Price
US $9.00-5.00/kg
Min. Order
1kg
Purity
99.9%
Supply Ability
200ton
Release date
2024-06-17
Hebei Mojin Biotechnology Co.,Ltd
Product
4-Acetoxyindole 5585-96-6
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
50000KG/month
Release date
2024-05-17
Henan Fengda Chemical Co., Ltd
Product
4-Acetoxyindole 5585-96-6
Price
US $35.00-1.20/kg
Min. Order
1kg
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-03-28

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