ChemicalBook > CAS DataBase List > MKC8866

MKC8866

Product Name
MKC8866
CAS No.
1338934-59-0
Chemical Name
MKC8866
Synonyms
181697;MKC8866;MKC8866;MKC-8866;IRE-1α inhibitor 1;IRE1 RNase inhibitor 8866;IRE1 RNase inhibitor 8866 (MKC8866;Inositol requiring enzyme 1,inhibit,MKC-8866,IRE1,MKC8866,Inhibitor,MKC 8866;7-hydroxy-6-methoxy-4-methyl-3-(2-morpholino-2-oxoethyl)-2-oxo-2H-chromene-8-carbaldehyde;2H-1-Benzopyran-8-carboxaldehyde, 7-hydroxy-6-methoxy-4-methyl-3-[2-(4-morpholinyl)-2-oxoethyl]-2-oxo-
CBNumber
CB44796671
Molecular Formula
C18H19NO7
Formula Weight
361.35
MOL File
1338934-59-0.mol
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MKC8866 Property

Boiling point:
620.0±55.0 °C(Predicted)
Density 
1.373±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMSO:16.67(Max Conc. mg/mL);46.13(Max Conc. mM)
form 
A solid
pka
6.20±0.20(Predicted)
color 
Light yellow to yellow
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Axon Medchem
Product number
Axon3223
Product name
MKC8866
Purity
99%
Packaging
5mg
Price
$115.5
Updated
2021/12/16
Axon Medchem
Product number
Axon3223
Product name
MKC8866
Purity
99%
Packaging
25mg
Price
$401.5
Updated
2021/12/16
ChemScene
Product number
CS-0026810
Product name
MKC8866
Purity
99.87%
Packaging
5mg
Price
$550
Updated
2021/12/16
Axon Medchem
Product number
Axon3223
Product name
MKC8866
Purity
99%
Packaging
2x25mg
Price
$616
Updated
2021/12/16
ChemScene
Product number
CS-0026810
Product name
MKC8866
Purity
99.87%
Packaging
10mg
Price
$850
Updated
2021/12/16
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MKC8866 Chemical Properties,Usage,Production

Biological Activity

MKC8866 (IRE1-IN-8866) is a salicylaldehyde analog, a specific IRE1α RNase inhibitor with IC50 of 0.29 μM against human IRE1α in vitro.

target

TargetValue
hIRE1α
(Cell-free assay)		 0.29 μM

MKC8866 Preparation Products And Raw materials

Raw materials

Preparation Products

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MKC8866 Suppliers

China 39 United States 3 Global 42
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32161
Advantage
58
Aladdin Scientific
Tel
+1-+1(833)-552-7181
Email
sales@aladdinsci.com
Country
United States
ProdList
57505
Advantage
58
Cayman Chemical Company
Tel
--
Fax
--
Email
cayman@caymanchem.com
Country
United States
ProdList
6213
Advantage
81

1338934-59-0, MKC8866Related Search:

MKC9989 GSK2656157 7Methyl-5-(1-{[3-(trifluoroMethyl)phenyl]acetyl}-2,3-dihydro1Hindol-5-yl)7Hpyrrolo[2,3d]pyriMidin-4-aMine MKC3946 ISRIB

  • MKC8866
  • 2H-1-Benzopyran-8-carboxaldehyde, 7-hydroxy-6-methoxy-4-methyl-3-[2-(4-morpholinyl)-2-oxoethyl]-2-oxo-
  • IRE1 RNase inhibitor 8866 (MKC8866
  • 7-hydroxy-6-methoxy-4-methyl-3-(2-morpholino-2-oxoethyl)-2-oxo-2H-chromene-8-carbaldehyde
  • MKC8866;MKC-8866
  • 181697
  • IRE1 RNase inhibitor 8866
  • Inositol requiring enzyme 1,inhibit,MKC-8866,IRE1,MKC8866,Inhibitor,MKC 8866
  • IRE-1α inhibitor 1
  • 1338934-59-0