Mono-tert-butyl docosanedioate

Product Name: Mono-tert-butyl docosanedioate
CAS No.: 1642333-05-8
Chemical Name: Mono-tert-butyl docosanedioate
Synonyms: Mono-tert-butyl docosanedioate;22-(tert-butoxy)-22-oxoicosanoic acid;22-(tert-Butoxy)-22-oxodocosanoic acid;Docosanedioic acid, 1-(1,1-dimethylethyl) ester;Docosanedioic acid, mono(1,1-dimethylethyl) ester
CBNumber: CB44798433
Molecular Formula: C26H50O4
Formula Weight: 426.67
MOL File: 1642333-05-8.mol

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Mono-tert-butyl docosanedioate Property

storage temp.: Storage temp. 2-8°C
form: powder
color: White
InChI: InChI=1S/C26H50O4/c1-26(2,3)30-25(29)23-21-19-17-15-13-11-9-7-5-4-6-8-10-12-14-16-18-20-22-24(27)28/h4-23H2,1-3H3,(H,27,28)
InChIKey: OXPWLSZVTHVKQN-UHFFFAOYSA-N
SMILES: C(OC(C)(C)C)(=O)CCCCCCCCCCCCCCCCCCCCC(O)=O

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Safety

HS Code: 2917198090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

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N-Bromosuccinimide Price

SynQuest Laboratories

Product number: 2123-1-87
Product name: 22-(tert-Butoxy)-22-oxodocosanoic acid
Packaging: 250mg
Price: $600
Updated: 2021/12/16

Activate Scientific

Product number: AS145122
Product name: 22-(tert-Butoxy)-22-oxodocosanoicacid
Purity: 97%
Packaging: 1g
Price: $1348
Updated: 2021/12/16

Ambeed

Product number: A1490292
Product name: 22-(tert-Butoxy)-22-oxodocosanoicacid
Purity: 98+%
Packaging: 250mg
Price: $25
Updated: 2021/12/16

Ambeed

Product number: A1490292
Product name: 22-(tert-Butoxy)-22-oxodocosanoicacid
Purity: 98+%
Packaging: 1g
Price: $62
Updated: 2021/12/16

Ambeed

Product number: A971470
Product name: 22-(tert-Butoxy)-22-oxodocosanoicacid
Purity: 97%
Packaging: 5g
Price: $209
Updated: 2021/12/16

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Mono-tert-butyl docosanedioate Chemical Properties,Usage,Production

Uses

22-(tert-Butoxy)-22-oxodocosanoic acid is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). 22-(tert-Butoxy)-22-oxodocosanoic acid is also a alkyl chain-based PROTAC linker that can be used in t

IC 50

Non-cleavable Linker

References

[1] Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017;16(5):315-337. DOI:10.1038/nrd.2016.268
[2] Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985. DOI:10.7554/eLife.57277

Mono-tert-butyl docosanedioate Preparation Products And Raw materials

Raw materials

Preparation Products

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Mono-tert-butyl docosanedioate Suppliers

China 54 United Kingdom 1 United States 4 Global 59

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Mono-tert-butyl docosanedioate

1642333-05-8