PRIMIN Property

Melting point:

77-79℃

Boiling point:

163 °C(Press: 3 Torr)

Density 

1.06±0.1 g/cm3 (20 ºC 760 Torr)

solubility 

Acetonitrile: soluble; Ethanol: soluble; Ethyl Acetate: soluble; Methanol: soluble

form 

A solid

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H302Harmful if swallowed

H312Harmful in contact with skin

H317May cause an allergic skin reaction

H332Harmful if inhaled

H334May cause allergy or asthma symptoms or breathing difficulties if inhaled

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P272Contaminated work clothing should not be allowed out of the workplace.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P285In case of inadequate ventilation wear respiratory protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P304+P341IF INHALED: If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing.

P312Call a POISON CENTER or doctor/physician if you feel unwell.

P321Specific treatment (see … on this label).

P322Specific measures (see …on this label).

P330Rinse mouth.

P333+P313IF SKIN irritation or rash occurs: Get medical advice/attention.

P342+P311IF experiencing respiratory symptoms: call a POISON CENTER or doctor/physician.

P363Wash contaminated clothing before reuse.

P501Dispose of contents/container to..…

PRIMIN Chemical Properties,Usage,Production

Description

Primin is the allergen of Primula obconica. Occupational contact dermatitis occurs mainly in florists and horticulturists.

Uses

Primin can be prepared to use for SAR docking and antioxidant activity due to the activity of COX/5-LOX inhibitors with quinone and resorcinol core. It can also be used for its cytotoxic mechanisms toward human acute lymphoblastic leukemia, multiple myeloma and acute myeloid leukemia cells.

Definition

ChEBI: A member of the class of 1,4-benzoquinones having a methoxy substituent at the 2-position and a pentyl substituent at the 6-position.

Contact allergens

Primin is the major allergen of Primula obconica Hance (Primulaceae family). Allergic contact dermatitis is mainly occupational, occurring in florists and horticulturists.