ChemicalBook > CAS DataBase List > 5-Nitroquinoline

5-Nitroquinoline

Product Name: 5-Nitroquinoline
CAS No.: 607-34-1
Chemical Name: 5-Nitroquinoline
Synonyms: AKOS 92273;5-NitroquinoL;5-Nitrochinolin;5-nitro-quinolin;5-NITROQUINOLINE;Quinoline,5-nitro-;5-Nitroquinoline>5-Nitroquinoline,99%;5-NITROQUINOLINE 98+%;5-Nitro-1-azanaphthalene
CBNumber: CB4484970
Molecular Formula: C9H6N2O2
Formula Weight: 174.16
MOL File: 607-34-1.mol

Less

5-Nitroquinoline Property

Melting point:: 71-73 °C (lit.)
Boiling point:: 70-73°C
Density: 1.2190 (estimate)
refractive index: 1.6820 (rough estimate)
storage temp.: Inert atmosphere,Room Temperature
Water Solubility: Slightly soluble in water
form: powder to crystal
pka: 2.80±0.12(Predicted)
color: Plates from EtOH (aq)
InChI: InChI=1S/C9H6N2O2/c12-11(13)9-5-1-4-8-7(9)3-2-6-10-8/h1-6H
InChIKey: NDDZXHOCOKCNBM-UHFFFAOYSA-N
SMILES: N1C2C(=C([N+]([O-])=O)C=CC=2)C=CC=1
CAS DataBase Reference: 607-34-1(CAS DataBase Reference)
NIST Chemistry Reference: Quinoline, 5-nitro-(607-34-1)
EPA Substance Registry System: 5-Nitroquinoline (607-34-1)

Less

Safety

Hazard Codes: Xn,Xi
Risk Statements: 20/21/22-40-68-36/37/38
Safety Statements: 7-22-36-45-36/37/39-26
WGK Germany: 3
RTECS: VC1850000
Hazard Note: Irritant
HS Code: 29334900
Toxicity: mmo-sat 10 mg/plate MUREAV 92,29,82

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H351Suspected of causing cancer

Precautionary statements

P201Obtain special instructions before use.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P308+P313IF exposed or concerned: Get medical advice/attention.

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: N23807
Product name: 5-Nitroquinoline
Purity: 99%
Packaging: 5g
Price: $83.8
Updated: 2023/06/20

TCI Chemical

Product number: N0344
Product name: 5-Nitroquinoline
Purity: >98.0%(GC)(T)
Packaging: 25g
Price: $39
Updated: 2025/07/31

TCI Chemical

Product number: N0344
Product name: 5-Nitroquinoline
Purity: >98.0%(GC)(T)
Packaging: 250g
Price: $225
Updated: 2025/07/31

TRC

Product number: N520148
Product name: 5-Nitroquinoline
Packaging: 250mg
Price: $45
Updated: 2021/12/16

AK Scientific

Product number: J51928
Product name: 5-Nitroquinoline
Packaging: 25g
Price: $45
Updated: 2021/12/16

Less

5-Nitroquinoline Chemical Properties,Usage,Production

Chemical Properties

white to light yellow crystal powder

Safety Profile

Mutation data reported. Whenheated to decomposition it emits toxic fumes of NOx. Seealso other nitroquinoline entries.

Synthesis

91-22-5

607-35-2

607-34-1

General procedure for the synthesis of 8-nitroquinoline and 5-nitroquinoline from quinoline: Pure sulfuric acid (H2SO4) was slowly added to 1 equivalent of quinoline at 0 °C. Subsequently, 3 equivalents of 65% nitric acid (HNO3) were added dropwise and the reaction mixture was stirred at room temperature for 1 hour. Upon completion of the reaction, the mixture was poured sequentially into ice water, neutralized with sodium carbonate (Na2CO3) to pH neutral, and then extracted twice with dichloromethane (DCM). The organic layers were combined, washed with water, dried over anhydrous sodium sulfate (Na2SO4) and finally the solvent was evaporated under vacuum. 8-Nitroquinoline (compound 35) was obtained as a light yellow solid in 34% yield; melting point 90 °C, literature value: 89-90 °C [43].1H NMR (200 MHz, CDCl3) δ: 7.53-7.66 (m, 2H), 8.04 (d, J = 8.0 Hz, 2H), 8.27 (dd, J = 1.6 and 8.4 Hz, 1H). 9.70 (dd, J = 1.7 and 4.2 Hz, 1H). 13C NMR (50 MHz, CDCl3) δ: 122.8 (CH), 123.8 (CH), 125.3 (CH), 129.0 (C), 132.0 (CH), 136.1 (CH), 139.5 (C), 148.2 (C), 152.6 (CH ). Recrystallization by isopropanol afforded 5-nitroquinoline (compound 36) as a light yellow solid in 38% yield; melting point 71 °C, literature value: 71-72 °C [41].1H NMR (200 MHz, CDCl3) δ: 7.61-7.68 (m, 1H), 7.76-7.85 (m, 1H), 8.36-8.45 (m, 2H). 8.98-9.04 (m, 2H).13C NMR (50MHz, CDCl3) δ: 121.2 (C), 123.9 (CH), 124.6 (CH), 127.5 (CH), 131.9 (CH), 136.6 (CH), 145.5 (C), 148.2 (C), 151.6 (C).

Purification Methods

Crystallise 5-nitroquinoline from pentane, then from *benzene. The hydrochloride has m 224o and the picrate has m 206o, 214o(from MeOH). [Beilstein 20 H 371, 20 II 235, 20 III/IV 3397.]

References

[1] European Journal of Medicinal Chemistry, 2012, vol. 54, p. 75 - 86
[2] European Journal of Medicinal Chemistry, 2018, vol. 155, p. 135 - 152
[3] Journal of the Chemical Society, 1892, vol. 61, p. 788
[4] Chemische Berichte, 1885, vol. 18, p. 1243
[5] Journal fuer Praktische Chemie (Leipzig), 1896, vol. <2> 53, p. 392

5-Nitroquinoline Preparation Products And Raw materials

Raw materials

Preparation Products

5-Hydroxyquinoline

Less

5-Nitroquinoline Suppliers

Americas 1 Austria 1 Belgium 2 China 183 Europe 4 Germany 5 India 14 Japan 5 Poland 1 Slovakia 1 Switzerland 3 The Netherlands 1 Ukraine 2 United Kingdom 18 United States 31 Global 272

SiChuang NanBu Honesty Technology Co., Ltd.

Tel: 0838-5675166 15883665058
Fax: 0838-5675535
Email: nbcxkj@126.com
Country: China
ProdList: 919
Advantage: 55

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 4006356688 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
ProdList: 40228
Advantage: 62

future industrial shanghai co., ltd

Tel: 400-0066400 13621662912
Fax: 021-55660885
Email: sales@jonln.com
Country: China
ProdList: 1995
Advantage: 65

TAIYUAN RHF CO.,LTD.

Tel: +86 351 7031519
Fax: +86 351 7031519
Email: sales@RHFChem.com
Country: China
ProdList: 2338
Advantage: 56

TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
Fax: 021-67121385
Email: Sales-CN@TCIchemicals.com
Country: China
ProdList: 24529
Advantage: 81

Beijing dtftchem Technology Co., Ltd.

Tel: 010-60275820 13031183356
Fax: 010-60270825
Email: elainezt@sina.com
Country: China
ProdList: 1390
Advantage: 62

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44801
Advantage: 61

Capot Chemical Co., Ltd

Tel: +86 (0) 571 85 58 67 18
Fax: 0086-571-85864795
Country: China
ProdList: 18207
Advantage: 66

Beijing Ouhe Technology Co., Ltd

Tel: 010-010-82967028 13522913783
Fax: +86-10-82967029
Email: 2355560935@qq.com
Country: China
ProdList: 12000
Advantage: 60

JinYan Chemicals(ShangHai) Co.,Ltd.

Tel: 13817811078
Fax: 86-021-50426522,50426273
Email: sales@jingyan-chemical.com
Country: China
ProdList: 9976
Advantage: 60

Jia Xing Isenchem Co.,Ltd

Tel: 0573-85285100 18627885956
Fax: 0573-85285100
Email: isenchem@163.com
Country: China
ProdList: 9309
Advantage: 66

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
Email: info@hanhongsci.com
Country: China
ProdList: 42934
Advantage: 64

China DongFan Chemical Co.,LTD

Tel: 86-0571-85151182
Fax: 86-0571-85151182
Country: China
ProdList: 5691
Advantage: 66

XiaoGan ShenYuan ChemPharm co,ltd

Tel: 15527621225
Email: 1791901229@qq.com
Country: China
ProdList: 6945
Advantage: 52

Shandong Xiya Chemical Co., Ltd

Tel: 4009903999 13355009207
Fax: 0539-6365991
Email: 3007715519@qq.com
Country: China
ProdList: 18729
Advantage: 57

Syntechem Co.,Ltd

Tel
Fax: E-Mail Inquiry
Email: info@syntechem.com
Country: China
ProdList: 12984
Advantage: 57

ChangZhou SIDU chemical Co., Ltd.

Tel: 0519-81291281 18015082300
Fax: 0519-81291281
Email: siduchem@hotmail.com
Country: China
ProdList: 274
Advantage: 62

Tianjin heowns Biochemical Technology Co., Ltd.

Tel: 400 638 7771
Email: sales@heowns.com
Country: China
ProdList: 14435
Advantage: 57

Shanghai Chem-Milestone Co., Ltd

Tel: 021-50273253 13641951838
Fax: +86-21-61294436
Email: chemmilestone@163.com
Country: China
ProdList: 151
Advantage: 62

Hunan Hui Bai Shi Biotechnology Co., Ltd.

Tel: 0731-85526065 13308475853
Email: ivy@hnhbsj.com
Country: China
ProdList: 7247
Advantage: 62

Aemon Chemical

Tel: 0086-755-86198205
Email: acinfo@aemonchem.com
Country: China
ProdList: 1931
Advantage: 57

Maya High Purity Chemicals

Tel: +86 (573) 82222445 (0)18006601000 452520369
Fax: +86 (573) 82222643
Email: sales@maya-r.com
Country: China
ProdList: 11707
Advantage: 57

Hangzhou Yuhao Chemical Technology Co., Ltd

Tel: 0571-82693216
Fax: +86-571-82880190
Email: info@yuhaochemical.com
Country: China
ProdList: 6387
Advantage: 52

Chengdu Ai Keda Chemical Technology Co., Ltd.

Tel: 4008-755-333 18080918076
Fax: 028-86757656
Email: 800078821@qq.com
Country: China
ProdList: 9718
Advantage: 55

Shanghai civi chemical technology co.,Ltd

Tel: 86-21-34053660
Fax: 86-21-34053661
Email: sale@labgogo.com
Country: China
ProdList: 9865
Advantage: 52

Thermo Fisher Scientific

Tel: 800-810-5118
Fax: +86-10-84193589
Email: cnchemical@thermofisher.com
Country: China
ProdList: 17770
Advantage: 75

Changzhou Fourman Chemical Co., Ltd.

Tel: 0519-89882557 13912311481
Fax: 0519-8988-2559
Email: fourmanchem@163.com
Country: China
ProdList: 63
Advantage: 60

Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.

Tel: 025-66113011 17798518460
Fax: (1)02557626880
Email: cfzhang@aikonchem.com
Country: China
ProdList: 19913
Advantage: 55

9ding chemical ( Shanghai) Limited

Tel: 4009209199
Fax: 86-021-52271987
Email: sales@9dingchem.com
Country: China
ProdList: 22514
Advantage: 55

Shanghai Aladdin Bio-Chem Technology Co.,LTD

Tel: 400-6206333 13167063860
Fax: 021-50323701
Email: anhua.mao@aladdin-e.com
Country: China
ProdList: 25003
Advantage: 65

The future of Shanghai Industrial Co., Ltd.

Tel: 021-61552785
Fax: 021-55660885
Email: sales@shshiji.com
Country: China
ProdList: 9546
Advantage: 55

Chengdu AstaTech Trading Co., Ltd./AstaTech (Chengdu) Pharma. Co., Ltd.

Tel: +86-28-85122536 85324413
Fax: +86-28-85326443
Email: market@astatech.cn
Country: China
ProdList: 8026
Advantage: 55

Quzhou HuntBio Co., Ltd.

Tel: 0571-64067827 13372408495
Fax: 0571-64067827
Email: sales@huntchem.com
Country: China
ProdList: 150
Advantage: 60

Chimica Laboratories Co., Ltd

Tel: 0086-573-82585213
Fax: 0086-573-82585233
Email: bai@chimicalabs.com
Country: China
ProdList: 861
Advantage: 64

Beijing Universal Century Technology Co., Ltd.

Tel: 400-8706899
Fax: 400-8706899
Email: hysj_bj.com
Country: China
ProdList: 3583
Advantage: 55

Shanghai JONLN Reagent Co., Ltd.

Tel: 400-0066400 13621662912
Fax: 021-55660885
Email: 422131432@qq.com
Country: China
ProdList: 9979
Advantage: 55

Beijin Yangguang Furui Chemical co.,Ltd.

Tel: 010-57495520 13521095525
Email: zhw512@foxmail.com
Country: China
ProdList: 488
Advantage: 55

Huainan Kedi Chemical Factory

Tel: 0554-2106669
Fax: 0554-2666215
Email: sales1@kedichem.com
Country: China
ProdList: 4924
Advantage: 55

Zaozhuang Benefit Chemical Co., Ltd.

Tel: 0531-69958783 15508681609
Fax: 0531-69958783
Email: 1948129184@qq.com
Country: China
ProdList: 205
Advantage: 60

Bide Pharmatech Ltd.

Tel: 400-164-7117 13681763483
Fax: +86-21-61629029
Email: product02@bidepharm.com
Country: China
ProdList: 39966
Advantage: 60

ShangHai D&B Biological Science and Technology Co.Ltd

Tel: 400-008-9730,021-54359730 400-008-9730
Fax: 021-54353864
Email: info@chemxyz.com
Country: China
ProdList: 3057
Advantage: 60

Chengdu HuaXia Chemical Reagent Co. Ltd

Tel: 400-1166-196 13458535857
Fax: QQ：800101999
Email: cdhxsj@163.com
Country: China
ProdList: 13350
Advantage: 58

Suzhou yacoo science co.,Ltd

Tel: 0512-87182056 18013166090
Fax: 0512-87182056
Email: lingling.qi@yacoo.com.cn
Country: China
ProdList: 6295
Advantage: 60

Credit-Chem Co., Ltd.

Tel: 400-821-5857 021-64326257
Fax: 021-64393586 QQ;2798200800
Email: credit-chem@foxmail.com
Country: China
ProdList: 5219
Advantage: 58

Wuhan Dahua Pharmaceutical Co., Ltd.

Tel: 027-59262863 13277907145 3091977954
Fax: 027-59420980
Country: China
ProdList: 4942
Advantage: 58

Shanghai YuLue Chemical Co., Ltd.

Tel: 021-60345187 13671753212
Fax: 021-34702061
Email: lzz841106@aliyun.com
Country: China
ProdList: 10263
Advantage: 55

Shanghai Song Yuan Chemical Technology Co., Ltd.

Tel: 010-1234567 18521000990
Fax: 86-021-33275113
Email: sonyuanchemical@163.com
Country: China
ProdList: 6479
Advantage: 50

Sigma-Aldrich

Tel: 021-61415566 800-8193336
Email: orderCN@merckgroup.com
Country: China
ProdList: 51395
Advantage: 80

Shanghai Send Pharmaceutical Technology Co., Ltd.

Tel: 021-58088081 Q2635253576
Fax: QQ3382968513
Email: hailey@shsendpharm.com
Country: China
ProdList: 1984
Advantage: 55

Less

View Lastest Price from 5-Nitroquinoline manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

Product: 5-Nitroquinoline 607-34-1
Price: US $3.00-9.00/KG
Min. Order: 0.1KG
Purity: 99%
Supply Ability: g-kg-tons, free sample is available
Release date: 2025-06-25

Henan Aochuang Chemical Co.,Ltd.

Product: 5-Nitroquinoline 607-34-1
Price: US $0.00-0.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 1Ton
Release date: 2022-10-12

Shanghai Rlavie Technology Co ltd

Product: 5-Nitroquinoline 607-34-1
Price: US $0.00-0.00/KG
Min. Order: 1g
Purity: 98%min
Supply Ability: 100kgs/month
Release date: 2022-01-03

607-34-1, 5-NitroquinolineRelated Search:

Ethoxyquin 6-Hydroxy-2(1H)-3,4-dihydroquinolinone Quinhydrone 8-Hydroxyquinoline 4-methylquinoline quinolinium hydrogen sulphate Isoquinoline Quinclorac 6-METHYL-5-NITROQUINOLINE 5-nitrobenzofuran 5-NITRO-1,10-PHENANTHROLINE-2,9-DICARBOXYLIC ACID 5-Nitro-1,10-phenanthroline 8-chloro-5-nitro-quinoline 6-BROMO-5-NITROQUINOLINE 7-METHYL-8-NITROQUINOLINE 1,2,3,4-TETRAHYDRO-7-NITROQUINOLINE 5-Amino-6-nitroquinoline Nitroxoline

5-nitro-quinolin

Quinoline,5-nitro-

5-NITROQUINOLINE

AKOS 92273

5-Nitroquinoline,99%

5-Nitrochinolin

5-NITROQUINOLINE 98+%

5-Nitro-1-azanaphthalene

5-Nitroquinoline≥ 98% (TLC)

5-Nitroquinoline&gt

5-NitroquinoL

5-Nitroquinoline ISO 9001：2015 REACH

607-34-1

O2NC9H5NCH3

Quinolines

Nitroquinolines

Building Blocks

Heterocyclic Building Blocks

Quinolines, Quinazolines and derivatives

Building Blocks

C8 to C10

Chemical Synthesis

Heterocyclic Building Blocks

Heterocycles

Quinoline&Isoquinoline

Quinolines

Nitroquinolines

Building Blocks

Heterocyclic Building Blocks