4-methylquinoline

Product Name: 4-methylquinoline
CAS No.: 491-35-0
Chemical Name: 4-methylquinoline
Synonyms: 4-METHYLQUINOLINE;4-Lepidine;4-METHYLCHINOLINE;Lepidin;epidine;LEPIDINE;Lepidine>Lepidine,98%;Lepidine ,99%;4-Methylchinol
CBNumber: CB8121295
Molecular Formula: C10H9N
Formula Weight: 143.19
MOL File: 491-35-0.mol

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4-methylquinoline Property

Melting point:: 9-10 °C(lit.)
Boiling point:: 261-263 °C(lit.)
Density: 1.083 g/mL at 25 °C(lit.)
refractive index: n20/D 1.620(lit.)
Flash point:: >230 °F
storage temp.: Refrigerator
solubility: Slightly soluble in water, miscible with alcohol and oils.
pka: 5.67(at 20℃)
form: Liquid
color: Pale Orange
Odor: at 100.00 %. burnt oily herbal floral sweet
Odor Type: burnt
Water Solubility: Slightly soluble
Sensitive: Light Sensitive
Merck: 14,5441
BRN: 110926
InChIKey: MUDSDYNRBDKLGK-UHFFFAOYSA-N
LogP: 2.610
CAS DataBase Reference: 491-35-0(CAS DataBase Reference)
NIST Chemistry Reference: Quinoline, 4-methyl-(491-35-0)
EPA Substance Registry System: Quinoline, 4-methyl- (491-35-0)

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Safety

Hazard Codes: Xi,Xn
Risk Statements: 36/37/38-68-40
Safety Statements: 26-36-45-36/37/39-22
WGK Germany: 3
RTECS: OH0316000
F: 8-10
TSCA: Yes
HS Code: 29334900
Hazardous Substances Data: 491-35-0(Hazardous Substances Data)

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 158283
Product name: Lepidine
Purity: 99%
Packaging: 25g
Price: $99.3
Updated: 2024/03/01

Sigma-Aldrich

Product number: 158283
Product name: Lepidine
Purity: 99%
Packaging: 100g
Price: $188
Updated: 2024/03/01

TCI Chemical

Product number: L0024
Product name: Lepidine
Purity: >97.0%(GC)(T)
Packaging: 25mL
Price: $59
Updated: 2024/03/01

TCI Chemical

Product number: L0024
Product name: Lepidine
Purity: >97.0%(GC)(T)
Packaging: 100mL
Price: $165
Updated: 2024/03/01

Alfa Aesar

Product number: A14040
Product name: Lepidine, 97%
Packaging: 10g
Price: $45.65
Updated: 2024/03/01

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4-methylquinoline Chemical Properties,Usage,Production

Description

Refer to 6-METHYLQUINOLINE.

Chemical Properties

clear slightly yellow to brown liquid

Physical properties

4-Methylquinoline is a colorless liquid with a weak quinoline-like odor. It is slightly soluble in water, miscible with many organic solvents, and volatile in steam.

Uses

4-Methylquinoline is used as a reagent in the synthesis of azetidine based ene-amides as potent bacterial enoyl ACP reductase inhibitors. Also used as a reagent in the synthesis of cyanine-styryl dyes with enhanced photostability for fluorescent DNA imaging.

Uses

4-methylquinoline is used mainly in flavor compositions for imitation Honey, Nut, Butter, Caramel, etc. and in certain fruit complexes. The concentration used is normally about 0.2 to 2 ppm in the finished product.

Production Methods

4-Methylquinoline can be recovered from the highest-boiling fraction of the coal-tar quinoline bases via its o-cresol addition compound. It can be synthesized by condensation of aniline and methyl vinyl ketone.

Definition

ChEBI: A methylquinoline carrying a methyl substituent at position 4.

Synthesis Reference(s)

Tetrahedron Letters, 28, p. 5291, 1987 DOI: 10.1016/S0040-4039(00)96710-8

General Description

Synthesis of lepidine from 4-anilinobutan-2-one in ethanol in the presence of HCl or FeCl₃has been reported. Nitration of lepidine has been reported.

Purification Methods

Reflux lepidine with BaO, then fractionally distil it. Further purify it via its recrystallised dichromate salt (m 138o) (from H2O). [Cumper et al. J Chem Soc 1176 1962.] [Beilstein 20 III/IV 3477, 20/7 V 389.]

4-methylquinoline Preparation Products And Raw materials

Raw materials

Xylene Acetoacetanilide ZINC Ammonium hydroxide Ethanol Zinc chloride Phosphorus oxychloride Phosphorus pentachloride Iron chloride hexahydrate Iodine Aniline Ethyl acetate Acetic acid Methyl vinyl ketone Phosphorus Sulfuric acid

Preparation Products

QUINOLINE-4-CARBOXYLIC ACID 4-Quinolinecarboxaldehyde METHYL 8-AMINOQUINOLINE-4-CARBOXYLATE

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4-methylquinoline Suppliers

Americas 1 Austria 1 Belgium 3 Canada 1 China 149 Europe 4 France 1 Germany 8 India 28 Japan 5 Lithuania 1 Slovakia 1 Switzerland 3 Ukraine 1 United Kingdom 14 United States 52 Global 273

Hangzhou Yaoruiyicheng Biological Medicine Co., Ltd

Tel: 18072846723; 18072846723
Email: caigou1@witofly.com
Country: China
ProdList: 311
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Shaanxi Dideu Medichem Co. Ltd

Tel: 029-81145920 13259709322
Fax: 029-88380327
Email: 1027@dideu.com
Country: China
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Wuhan EnTai Technology Development Co,.Ltd

Tel: 86-27-82330560
Fax: 86-27-82330547
Email: 2536851935@qq.com
Country: China
ProdList: 347
Advantage: 69

Meryer (Shanghai) Chemical Technology Co., Ltd.

Tel: 021-61259108 18621169109
Fax: 86-21-61259102
Email: market03@meryer.com
Country: China
ProdList: 40228
Advantage: 62

INTATRADE GmbH

Tel: +49 3493/605464
Fax: +49 3493/605470
Email: sales@intatrade.de
Country: Germany
ProdList: 3572
Advantage: 66

Alfa Aesar

Tel: 400-6106006
Fax: 021-67582001/03/05
Email: saleschina@alfa-asia.com
Country: China
ProdList: 30123
Advantage: 84

TCI (Shanghai) Development Co., Ltd.

Tel: 021-67121386
Fax: 021-67121385
Email: Sales-CN@TCIchemicals.com
Country: China
ProdList: 24529
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Beijing dtftchem Technology Co., Ltd.

Tel: 010-60275820 13031183356
Fax: 010-60270825
Email: elainezt@sina.com
Country: China
ProdList: 1390
Advantage: 62

Energy Chemical

Tel: 021-021-58432009 400-005-6266
Fax: 021-58436166
Email: sales8178@energy-chemical.com
Country: China
ProdList: 44689
Advantage: 61

Jia Xing Isenchem Co.,Ltd

Tel: 0573-85285100 18627885956
Fax: 0573-85285100
Email: isenchem@163.com
Country: China
ProdList: 9414
Advantage: 66

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View Lastest Price from 4-methylquinoline manufacturers

Hebei Weibang Biotechnology Co., Ltd

Product: Lepidine 491-35-0
Price: US $10.00/PCS
Min. Order: 1KG
Purity: 99%
Supply Ability: 100 mt
Release date: 2021-04-12

Hebei Mojin Biotechnology Co., Ltd

Product: 4-methylquinoline 491-35-0
Price: US $0.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 50000KG/month
Release date: 2023-08-25

Career Henan Chemical Co

Product: Lepidine 491-35-0
Price: US $1.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 100KG
Release date: 2018-12-22

491-35-0, 4-methylquinolineRelated Search:

8-Hydroxyquinoline quinolinium hydrogen sulphate Ethoxyquin 8-Methylquinoline Quinclorac Isoquinoline 2-HYDROXY-4-METHYLQUINOLINE 6-Hydroxy-2(1H)-3,4-dihydroquinolinone Quinhydrone CINCHOPHEN 1,1'-DIETHYL-4,4'-CARBOCYANINE IODIDE QUINOLINE-4-CARBOXYLIC ACID Lepidine, 2-chloro- Bathophenanthroline 2,4-DIMETHYLQUINOLINE BATHOPHENANTHROLINEDISULFONIC ACID DISODIUM SALT TRIHYDRATE 3,4,7,8-Tetramethyl-1,10-phenanthroline 4,7-Dimethyl-1,10-phenanthroline

4-METHYLQUINUOLINE

4-METHYLQUINOLINE 99+%

LEPIDINE, 99% (4-METHYLQUINOLINE)

Lepidine(4-Methylquinoline)99%

Lepidine,98%

4-Methylquinoline, Lepidine

Lepidine ,99%

4-Methylquinoline,4-Methylquinoline, Lepidine

Lepidine, 99% 100GR

Lepidine, 99% 25GR

4-Methylchinolin

4-Methylchinol

4-Methylquinoline≥ 99% (GC)

4-methyl-quinolin

Cincholepidine

gamma-Methylquinoline

Lepidin

-Methylquinoline

Quinoline,4-methyl-

4-METHYLQUINOLINE

4-METHYLCHINOLINE

4-Lepidine

LEPIDINE

Lepidine&gt

epidine

Lepidine ISO 9001：2015 REACH

Lepidine, ≥ 97.0%

Atazanavir Impurity 45

3-(4'-Methylbenzylidene)camphor

4-Methylquinoline in isooctane

491-35-0

C10H9N1

Alkylquinolines

Quinolines

Building Blocks

Heterocyclic Building Blocks

Alkylquinolines

Quinolines

Quinoline Derivertives

Quinoline series