Description Preparation
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2-CHLOROLEPIDINE

Description Preparation
Product Name
2-CHLOROLEPIDINE
CAS No.
634-47-9
Chemical Name
2-CHLOROLEPIDINE
Synonyms
AKOS BB-6898;Chlorolepidine;3-chlorolepidine;2-CHLOROLEPIDINE;AKOS BBS-00000215;Lepidine, 2-chloro-;2-Chlorolepidine >OTAVA-BB BB0116110026;2-chloro-4-methyl-quinolin;2-CHLORO-4-METHYLQUINOLINE
CBNumber
CB9663910
Molecular Formula
C10H8ClN
Formula Weight
177.63
MOL File
634-47-9.mol
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2-CHLOROLEPIDINE Property

Melting point:
55-58 °C(lit.)
Boiling point:
296 °C(lit.)
Density 
1.1810 (rough estimate)
refractive index 
1.6224 (estimate)
Flash point:
296°C
storage temp. 
Inert atmosphere,Room Temperature
form 
powder to crystal
pka
0.98±0.50(Predicted)
color 
White to Almost white
BRN 
118333
CAS DataBase Reference
634-47-9(CAS DataBase Reference)
NIST Chemistry Reference
Quinoline, 2-chloro-4-methyl-(634-47-9)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-37/39-36-24/25
WGK Germany 
3
HS Code 
29334900
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TCI Chemical
Product number
C0191
Product name
2-Chlorolepidine
Purity
>98.0%(GC)
Packaging
5g
Price
$44
Updated
2024/03/01
TCI Chemical
Product number
C0191
Product name
2-Chlorolepidine
Purity
>98.0%(GC)
Packaging
25g
Price
$146
Updated
2024/03/01
Alfa Aesar
Product number
H26504
Product name
2-Chloro-4-methylquinoline, 99%
Packaging
5g
Price
$47.65
Updated
2024/03/01
Alfa Aesar
Product number
H26504
Product name
2-Chloro-4-methylquinoline, 99%
Packaging
25g
Price
$151.65
Updated
2024/03/01
TRC
Product number
C587370
Product name
2-Chloro-4-methyl-quinoline
Packaging
5G
Price
$55
Updated
2021/12/16
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2-CHLOROLEPIDINE Chemical Properties,Usage,Production

Description

4-Methyl-2-chloro-quinoline is an organic intermediate. It has been reported that it can be used to prepare graphite electrodes based on CrO-FeO-PbO and quinoline modified and a modified vermiculite adsorbent for the adsorption and removal of benzene in chemical wastewater.

Preparation

The mixture of 2-hydroxy-4-methylquinoline and phosphorus oxychloride was heated to 80-85°C. After the solid was completely dissolved, the mixture was poured into ice water, the mixture was extracted with ether, and the ether extract was distilled out of ether. Afterwards, carry out vacuum distillation, collect 132-135 ℃ (0.4kPa) fraction, namely 2-chloro-4-methylquinoline. For further purification, petroleum ether (boiling point 40-50°C) can be used for recrystallization, and the yield is 86%-89%.

Chemical Properties

white to light yellow crystal powder

Uses

2-Chloro-4-methyl-quinoline is a useful synthetic intermediate. It is an intermediate used to synthesize 4-Methyl-2-(1-piperidinyl)-quinoline (M320715) which is a potent inhibitor of TRPC4 channels, responsible for various stimulation, muscle response due to interaction with the environment. 2-Chloro-4-methyl-quinoline is also considered as a cyanine dye.

Synthesis Reference(s)

Journal of the American Chemical Society, 63, p. 2367, 1941 DOI: 10.1021/ja01854a016
Organic Syntheses, Coll. Vol. 3, p. 194, 1955

2-CHLOROLEPIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

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2-CHLOROLEPIDINE Suppliers

Baiyin Chengze Chemical Technology Co., Ltd.
Tel
+86 943-8535351 13389336721
Fax
+86-943-8535351
Email
sales@chengzechem.com
Country
China
ProdList
294
Advantage
58
J & K SCIENTIFIC LTD.
Tel
010-82848833 400-666-7788
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
021-61259108 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
TCI (Shanghai) Development Co., Ltd.
Tel
021-67121386
Fax
021-67121385
Email
Sales-CN@TCIchemicals.com
Country
China
ProdList
24529
Advantage
81
ShangHai DEMO Chemical Co.,Ltd
Tel
400-021-7337 2355568890
Fax
0086-21-50182339
Email
sales@demochem.com
Country
China
ProdList
2572
Advantage
57
Energy Chemical
Tel
021-021-58432009 400-005-6266
Fax
021-58436166
Email
sales8178@energy-chemical.com
Country
China
ProdList
44689
Advantage
61
Capot Chemical Co., Ltd
Tel
+86 (0) 571 85 58 67 18
Fax
0086-571-85864795
Email
sales@capotchem.com
Country
China
ProdList
18207
Advantage
66
Accela ChemBio Co.,Ltd.
Tel
021-50795510 4000665055
Fax
021-50795055
Email
sales@accelachem.com
Country
China
ProdList
11655
Advantage
64
Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
ProdList
19172
Advantage
64
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View Lastest Price from 2-CHLOROLEPIDINE manufacturers

Hebei Zhanyao Biotechnology Co. Ltd
Product
2-CHLOROLEPIDINE 634-47-9
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
20 Tons
Release date
2021-10-14
Career Henan Chemical Co
Product
2-CHLOROLEPIDINE 634-47-9
Price
US $1.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
100KG
Release date
2018-12-21

634-47-9, 2-CHLOROLEPIDINERelated Search:


  • AKOS BBS-00000215
  • AKOS BB-6898
  • OTAVA-BB BB0116110026
  • 2-CHLOROLEPIDINE
  • 2-CHLORO-4-METHYLQUINOLINE
  • 2-chloro-4-methyl-quinolin
  • Chlorolepidine
  • 3-chlorolepidine
  • 2-Chloro-4-methylquinoline, 2-Chlorolepidine
  • Lepidine, 2-chloro-
  • 2-Chlorolepidine &gt
  • Quinoline, 2-chloro-4-methyl-
  • 2-CHLOROLEPIDINE ISO 9001:2015 REACH
  • 634-47-9
  • Building Blocks
  • Halogenated Heterocycles
  • Heterocyclic Building Blocks
  • Haloquinolines
  • Quinolines
  • Alkylquinolines
  • Quinoline&Isoquinoline
  • Alkylquinolines
  • Haloquinolines
  • Quinolines