2-CHLOROLEPIDINE

Description Preparation

Product Name: 2-CHLOROLEPIDINE
CAS No.: 634-47-9
Chemical Name: 2-CHLOROLEPIDINE
Synonyms: AKOS BB-6898;Chlorolepidine;3-chlorolepidine;2-CHLOROLEPIDINE;AKOS BBS-00000215;Lepidine, 2-chloro-;2-Chlorolepidine >OTAVA-BB BB0116110026;2-chloro-4-methyl-quinolin;2-CHLORO-4-METHYLQUINOLINE
CBNumber: CB9663910
Molecular Formula: C10H8ClN
Formula Weight: 177.63
MOL File: 634-47-9.mol

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2-CHLOROLEPIDINE Property

Melting point:: 55-58 °C(lit.)
Boiling point:: 296 °C(lit.)
Density: 1.1810 (rough estimate)
refractive index: 1.6224 (estimate)
Flash point:: 296°C
storage temp.: Inert atmosphere,Room Temperature
form: powder to crystal
pka: 0.98±0.50(Predicted)
color: White to Almost white
BRN: 118333
CAS DataBase Reference: 634-47-9(CAS DataBase Reference)
NIST Chemistry Reference: Quinoline, 2-chloro-4-methyl-(634-47-9)

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Safety

Hazard Codes: Xi
Risk Statements: 36/37/38
Safety Statements: 26-37/39-36-24/25
WGK Germany: 3
HS Code: 29334900

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TCI Chemical

Product number: C0191
Product name: 2-Chlorolepidine
Purity: >98.0%(GC)
Packaging: 5g
Price: $44
Updated: 2024/03/01

TCI Chemical

Product number: C0191
Product name: 2-Chlorolepidine
Purity: >98.0%(GC)
Packaging: 25g
Price: $146
Updated: 2024/03/01

Alfa Aesar

Product number: H26504
Product name: 2-Chloro-4-methylquinoline, 99%
Packaging: 5g
Price: $47.65
Updated: 2024/03/01

Alfa Aesar

Product number: H26504
Product name: 2-Chloro-4-methylquinoline, 99%
Packaging: 25g
Price: $151.65
Updated: 2024/03/01

TRC

Product number: C587370
Product name: 2-Chloro-4-methyl-quinoline
Packaging: 5G
Price: $55
Updated: 2021/12/16

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2-CHLOROLEPIDINE Chemical Properties,Usage,Production

Description

4-Methyl-2-chloro-quinoline is an organic intermediate. It has been reported that it can be used to prepare graphite electrodes based on CrO-FeO-PbO and quinoline modified and a modified vermiculite adsorbent for the adsorption and removal of benzene in chemical wastewater.

Preparation

The mixture of 2-hydroxy-4-methylquinoline and phosphorus oxychloride was heated to 80-85°C. After the solid was completely dissolved, the mixture was poured into ice water, the mixture was extracted with ether, and the ether extract was distilled out of ether. Afterwards, carry out vacuum distillation, collect 132-135 ℃ (0.4kPa) fraction, namely 2-chloro-4-methylquinoline. For further purification, petroleum ether (boiling point 40-50°C) can be used for recrystallization, and the yield is 86%-89%.

Chemical Properties

white to light yellow crystal powder

Uses

2-Chloro-4-methyl-quinoline is a useful synthetic intermediate. It is an intermediate used to synthesize 4-Methyl-2-(1-piperidinyl)-quinoline (M320715) which is a potent inhibitor of TRPC4 channels, responsible for various stimulation, muscle response due to interaction with the environment. 2-Chloro-4-methyl-quinoline is also considered as a cyanine dye.

Synthesis Reference(s)

Journal of the American Chemical Society, 63, p. 2367, 1941 DOI: 10.1021/ja01854a016
Organic Syntheses, Coll. Vol. 3, p. 194, 1955

2-CHLOROLEPIDINE Preparation Products And Raw materials

Raw materials

2-HYDROXY-4-METHYLQUINOLINE Phosphorus oxychloride

Preparation Products

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2-CHLOROLEPIDINE Suppliers

Americas 1 China 118 Europe 1 Germany 4 India 9 Japan 2 Lithuania 2 South Korea 1 Switzerland 1 Ukraine 1 United Kingdom 16 United States 25 Global 181

TCI Chemicals (India) Pvt. Ltd.

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TSK Lifesciences

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Reax Chemicals

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Oceanic Pharmachem Pvt. Ltd.

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Auro Pharmaceuticals & Fine Chemicals Pvt. Ltd

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Siri Life Sciences Pvt Ltd

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A.J Chemicals

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Dr. Jagath Reddy's Heterocyclics

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View Lastest Price from 2-CHLOROLEPIDINE manufacturers

Hebei Zhanyao Biotechnology Co. Ltd

Product: 2-CHLOROLEPIDINE 634-47-9
Price: US $10.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20 Tons
Release date: 2021-10-14

Career Henan Chemical Co

Product: 2-CHLOROLEPIDINE 634-47-9
Price: US $1.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 100KG
Release date: 2018-12-21

634-47-9, 2-CHLOROLEPIDINERelated Search:

5-Chloroquinaldine 4-CHLORO-2-METHYLQUINOLINE 7-Chloro-2-methylquinoline 2-CHLOROLEPIDINE 2-CHLOROQUINOLINE-4-CARBOXYLIC ACID 6-BROMO-2-CHLOROQUINOLINE-4-CARBOXYLIC ACID, 97 4-methylquinoline 2-Chloroquinoline IFLAB-BB F0016-0970 METHYL 6-BROMO-2-CHLOROQUINOLINE-4-CARBOXYLATE 2-CHLORO-4,6-DIMETHYL-QUINOLINE 6-BROMO-2-CHLOROQUINOLINE-4-CARBONYL CHLORIDE 2,6-DIMETHOXY-4-METHYLQUINOLINE 6-CHLOROLEPIDINE 2-CHLORO-4-PHENYLQUINOLINE 6-BROMO-2-CHLORO-4-PHENYLQUINOLINE 2-CHLORO-4,7-DIMETHYLQUINOLINE N,N-Diethyl-2-chloroquinoline-4-carboxamide

AKOS BBS-00000215

AKOS BB-6898

OTAVA-BB BB0116110026

2-CHLOROLEPIDINE

2-CHLORO-4-METHYLQUINOLINE

2-chloro-4-methyl-quinolin

Chlorolepidine

3-chlorolepidine

2-Chloro-4-methylquinoline, 2-Chlorolepidine

Lepidine, 2-chloro-

2-Chlorolepidine &gt

Quinoline, 2-chloro-4-methyl-

2-CHLOROLEPIDINE ISO 9001：2015 REACH

634-47-9

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