MAST CELL DEGRANULATING PEPTIDE
- Product Name
- MAST CELL DEGRANULATING PEPTIDE
- CAS No.
-
32908-73-9
- Chemical Name
- MAST CELL DEGRANULATING PEPTIDE
- Synonyms
- MCD;isulfide);MCD PEPTIDE;Peptide 401;IKCNCKRHVIKPHICRKICGKN-NH2;MCD PEPTIDE (APIS MELLIFERA);MAST CELL DEGRANULATING PEPTIDE;MAST CELL DEGRANULATING (MCD) PEPTIDE;mastcelldegranulatingpeptide(honeybee);MCD-PEPTIDE (HONEYBEE, APIS MELLIFERA)
- CBNumber
- CB4493264
- Molecular Formula
- C110H192N40O24S4
- Formula Weight
- 2587.24
- MOL File
- 32908-73-9.mol
MAST CELL DEGRANULATING PEPTIDE Property
- Density
- 1.50±0.1 g/cm3(Predicted)
- storage temp.
- −20°C
- solubility
- Soluble in DMSO
Safety
- WGK Germany
- 3
- RTECS
- OQ5980000
Hazard and Precautionary Statements (GHS)
N-Bromosuccinimide Price
ChemScene
- Product number
- CS-7079
- Product name
- Peptide401
- Purity
- 98.29%
- Packaging
- 500ug
- Price
- $336
- Updated
- 2021/12/16
Biorbyt Ltd
- Product number
- orb99641
- Product name
- Mast Cell Degranulating peptide
- Purity
- Greater than 98 % purified
- Packaging
- 0.5mg
- Price
- $408
- Updated
- 2021/12/16
ChemScene
- Product number
- CS-7079
- Product name
- Peptide401
- Purity
- 98.29%
- Packaging
- 1mg
- Price
- $576
- Updated
- 2021/12/16
Biorbyt Ltd
- Product number
- orb99642
- Product name
- Mast Cell Degranulating peptide
- Purity
- Greater than 98 % purified
- Packaging
- 1mg
- Price
- $595
- Updated
- 2021/12/16
American Custom Chemicals Corporation
- Product number
- PEP0002440
- Product name
- MAST CELL DEGRANULATING PEPTIDE
- Purity
- 95.00%
- Packaging
- 0.5MG
- Price
- $726.73
- Updated
- 2021/12/16
MAST CELL DEGRANULATING PEPTIDE Chemical Properties,Usage,Production
Biological Activity
Peptide 401 is a potent mast cell degranulation peptide derived from bee venom that inhibits vascular permeability.
in vivo
Peptide 401 substantially inhibits the oedema provoked by subplantar injection of carrageenin or intra-articular injection of turpentine in the rat. The ED 50 of 401 is c. 0.1 mg/kg. The anti-inflammatory effect is assessed by measurement of the increased 125 I-albumin content of an injected site in comparison with an uninjected contralateral site. Peptide 401 also suppresses the increased vascular permeability due to intradermal injection of various smooth muscle spasmogens (histamine, bradykinin, 5-hydroxytryptamine (5-HT), and prostaglandins). Peptide 401 (MCD peptide) contains 22 residues and occurs in the venom of the common European honey bee to the extent of about 2% by weight . It has powerful anti-inflammatory activity (at doses as low as 0.1 mg/kg) in a variety of animal models, ie, hind paw oedema in the rat induced by carrageenin or turpentine, adjuvant arthritis in the rat, and increased skin permeability in the rat resulting from subcut aneous injection of bradykinin, prostaglandin E1 kallikrein, histamine and 5-hydroxytryptamine (5-HT). It has a powerful degranulating effect on mast cells and involves the release of histamine and other pharmacologically active agents.
target
| serotonin | Histamine Receptor | < /table>
MAST CELL DEGRANULATING PEPTIDE Preparation Products And Raw materials
Raw materials
Preparation Products
MAST CELL DEGRANULATING PEPTIDE Suppliers
- Tel
-
- Country
- China
- ProdList
- 42982
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- 64
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- 021-50135380
- Email
- shchemsky@sina.com
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- China
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- 15421
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- 60
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- 0551-65326643 18156095617
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- 0551-65326641
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- info@cellmano.com
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- China
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- 1011
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- 021-58955995
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- 609-228-5909
- Email
- sales@medchemexpress.cn
- Country
- United States
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- 4863
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- 58
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- 0510-85629785 18013409632
- Fax
- 051085625359
- Email
- sales@reading-chemicals.com
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- China
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-
- Email
- info@creative-peptides.com
- Country
- United States
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- 6084
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- 021-52907766-8042
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- 021-52906523
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- China
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- 17705183659
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- 84523390
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- sales@njleonbiotech.com
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- China
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- 025-025-58361106-805-805 13082558573
- Fax
- 025-58361106-806
- Email
- liugang@njpeptide.com
- Country
- China
- ProdList
- 9962
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- 55
- Tel
- +86-17380623303 +86-17380623303
- Fax
- 028-62328193
- Email
- Caroline@youngshechem.com
- Country
- China
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View Lastest Price from MAST CELL DEGRANULATING PEPTIDE manufacturers
Career Henan Chemical Co
- Product
- MAST CELL DEGRANULATING PEPTIDE 32908-73-9
- Price
-
US $7.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 100KG
- Release date
- 2020-02-16
32908-73-9, MAST CELL DEGRANULATING PEPTIDERelated Search:
H-ILE-LYS-+CYS-ASN-++CYS-LYS-ARG-HIS-VAL-ILE-LYS-PRO-HIS-ILE-+CYS-ARG-LYS- ILE-++CYS-GLY-LYS-ASN-NH2
H-ILE-LYS-CYS-ASN-CYS-LYS-ARG-HIS-VAL-ILE-LYS-PRO-HIS-ILE-CYS-ARG-LYS-ILE-CYS-GLY-LYS-ASN-NH2
H-ILE-LYS-CYS-ASN-CYS-LYS-ARG-HIS-VAL-ILE-LYS-PRO-HIS-ILE-CYS-ARG-LYS-ILE-CYS-GLY-LYS-ASN-NH2 (RANDOM CYCLIZATION)
IKCNCKRHVIKPHICRKICGKN-NH2
ILE-LYS-CYS-ASN-CYS-LYS-ARG-HIS-VAL-ILE-LYS-PRO-HIS-ILE-CYS-ARG-LYS-ILE-CYS-GLY-LYS-ASN-NH2
MAST CELL DEGRANULATING PEPTIDE
MAST CELL DEGRANULATING PEPTIDE (APIS MELLIFERA)
MAST CELL DEGRANULATING (MCD) PEPTIDE
MCD PEPTIDE
MCD PEPTIDE (APIS MELLIFERA)
MCD
isulfide)
mastcelldegranulatingpeptide(honeybee)
mastcelldegranulatingpeptide(honeybeereduced)cyclic(3-15),(5-19)-bis(d
MCD-PEPTIDE (HONEYBEE, APIS MELLIFERA)
L-Ile-L-Lys-L-Cys(1)-L-Asn-L-Cys(2)-L-Lys-L-Arg-L-His-L-Val-L-Ile-L-Lys-L-Pro-L-His-L-Ile-L-Cys(1)-L-Arg-L-Lys-L-Ile-L-Cys(2)-Gly-L-Lys-L-Asn-NH2
Peptide 401
Mast Cell Degranulating (MCD) Peptide
Peptide 401
L-Aspartamide, L-isoleucyl-L-lysyl-L-cysteinyl-L-asparaginyl-L-cysteinyl-L-lysyl-L-arginyl-L-histidyl-L-valyl-L-isoleucyl-L-lysyl-L-prolyl-L-histidyl-L-isoleucyl-L-cysteinyl-L-arginyl-L-lysyl-L-isoleucyl-L-cysteinylglycyl-L-lysyl-, cyclic (3→15),(5→19)-bis(disulfide)
32908-73-9
C110H192N40O24S4
Voltage-gated Ion Channels
Ion Channels
Potassium Channel Modulators
Monovalent Ion Channels
BioChemical
Cell Signaling and Neuroscience
Cell Biology