MAST CELL DEGRANULATING PEPTIDE

Product Name: MAST CELL DEGRANULATING PEPTIDE
CAS No.: 32908-73-9
Chemical Name: MAST CELL DEGRANULATING PEPTIDE
Synonyms: MCD;isulfide);MCD PEPTIDE;Peptide 401;IKCNCKRHVIKPHICRKICGKN-NH2;MCD PEPTIDE (APIS MELLIFERA);MAST CELL DEGRANULATING PEPTIDE;MAST CELL DEGRANULATING (MCD) PEPTIDE;mastcelldegranulatingpeptide(honeybee);MCD-PEPTIDE (HONEYBEE, APIS MELLIFERA)
CBNumber: CB4493264
Molecular Formula: C110H192N40O24S4
Formula Weight: 2587.24
MOL File: 32908-73-9.mol

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MAST CELL DEGRANULATING PEPTIDE Property

Density: 1.50±0.1 g/cm3(Predicted)
storage temp.: −20°C
solubility: Soluble in DMSO
form: Solid
color: White to off-white

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Safety

WGK Germany: 3
RTECS: OQ5980000

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene

Product number: CS-7079
Product name: Peptide401
Purity: 98.29%
Packaging: 500ug
Price: $336
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb99641
Product name: Mast Cell Degranulating peptide
Purity: Greater than 98 % purified
Packaging: 0.5mg
Price: $408
Updated: 2021/12/16

ChemScene

Product number: CS-7079
Product name: Peptide401
Purity: 98.29%
Packaging: 1mg
Price: $576
Updated: 2021/12/16

Biorbyt Ltd

Product number: orb99642
Product name: Mast Cell Degranulating peptide
Purity: Greater than 98 % purified
Packaging: 1mg
Price: $595
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: PEP0002440
Product name: MAST CELL DEGRANULATING PEPTIDE
Purity: 95.00%
Packaging: 0.5MG
Price: $726.73
Updated: 2021/12/16

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MAST CELL DEGRANULATING PEPTIDE Chemical Properties,Usage,Production

Biological Activity

Peptide 401 is a potent mast cell degranulation peptide derived from bee venom that inhibits vascular permeability.

in vivo

Peptide 401 substantially inhibits the oedema provoked by subplantar injection of carrageenin or intra-articular injection of turpentine in the rat. The ED ₅₀ of 401 is c. 0.1 mg/kg. The anti-inflammatory effect is assessed by measurement of the increased ¹²⁵ I-albumin content of an injected site in comparison with an uninjected contralateral site. Peptide 401 also suppresses the increased vascular permeability due to intradermal injection of various smooth muscle spasmogens (histamine, bradykinin, 5-hydroxytryptamine (5-HT), and prostaglandins). Peptide 401 (MCD peptide) contains 22 residues and occurs in the venom of the common European honey bee to the extent of about 2% by weight . It has powerful anti-inflammatory activity (at doses as low as 0.1 mg/kg) in a variety of animal models, ie, hind paw oedema in the rat induced by carrageenin or turpentine, adjuvant arthritis in the rat, and increased skin permeability in the rat resulting from subcut aneous injection of bradykinin, prostaglandin E1 kallikrein, histamine and 5-hydroxytryptamine (5-HT). It has a powerful degranulating effect on mast cells and involves the release of histamine and other pharmacologically active agents.

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MAST CELL DEGRANULATING PEPTIDE Preparation Products And Raw materials

Raw materials

Preparation Products

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MAST CELL DEGRANULATING PEPTIDE Suppliers

China 56 Switzerland 1 United States 7 Global 64

Shanghai Hanhong Scientific Co.,Ltd.

Tel: 021-54306202 13764082696
Email: info@hanhongsci.com
Country: China
ProdList: 42958
Advantage: 64

Chemsky (shanghai) International Co.,Ltd

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 15402
Advantage: 60

Cellmano Biotech Limited

Tel: 0551-65326643 18156095617
Fax: 0551-65326641
Email: info@cellmano.com
Country: China
ProdList: 1011
Advantage: 55

MedChemexpress LLC

Tel: 021-58955995
Fax: 609-228-5909
Email: sales@medchemexpress.cn
Country: United States
ProdList: 4861
Advantage: 58

Wuxi Zhongkun Biochemical Technology Co., Ltd.

Tel: 0510-85629785 18013409632
Fax: 051085625359
Email: sales@reading-chemicals.com
Country: China
ProdList: 15178
Advantage: 58

Creative Peptides

Tel
Email: info@creative-peptides.com
Country: United States
ProdList: 6083
Advantage: 56

Codow Chemical Co.,Ltd.

Tel: 18620099427
Fax: +86-20-62619665
Email: amy@howeipharm.com
Country: China
ProdList: 17687
Advantage: 55

Shanghai Xilong Biochemical Technology Co., Ltd.

Tel: 021-52907766-8042
Fax: 021-52906523
Country: China
ProdList: 9941
Advantage: 58

Nanjing Leon Biological Technology Co., Ltd.

Tel: 17705183659
Fax: 84523390
Email: sales@njleonbiotech.com
Country: China
ProdList: 5501
Advantage: 55

Nanjing Peptide Biotech Ltd.

Tel: 025-025-58361106-805-805 13082558573
Fax: 025-58361106-806
Email: liugang@njpeptide.com
Country: China
ProdList: 9980
Advantage: 55

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View Lastest Price from MAST CELL DEGRANULATING PEPTIDE manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: MAST CELL DEGRANULATING PEPTIDE 32908-73-9
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 20T
Release date: 2024-08-13

Career Henan Chemical Co

Product: MAST CELL DEGRANULATING PEPTIDE 32908-73-9
Price: US $7.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 100KG
Release date: 2020-02-16

32908-73-9, MAST CELL DEGRANULATING PEPTIDERelated Search:

3':5'-CYCLIC-NUCLEOTIDE 5'-NUCLEOTIDOHYDROLASE ECHISTATIN PHOSPHOLIPASE A2 MASTOPARAN 17 VAL-ASP-TRP-LYS-LYS-ILE-GLY-GLN-HIS-ILE-LEU-SER-VAL-LEU-NH2 MU-CONOTOXIN GIIIA Desacetylcinobufagin 19-Hydroxybufalin MAS 7 MAST CELL DEGRANULATING PEPTIDE HR-1 MAST CELL DEGRANULATING PEPTIDE HR-2 ENTEROTOXIN STP (E COLI) CHLOROTOXIN SHK NA CYS-GLY MAST CELL DEGRANULATING PEPTIDE MAST CELL DEGRANULATING PEPTIDE

H-ILE-LYS-+CYS-ASN-++CYS-LYS-ARG-HIS-VAL-ILE-LYS-PRO-HIS-ILE-+CYS-ARG-LYS- ILE-++CYS-GLY-LYS-ASN-NH2

H-ILE-LYS-CYS-ASN-CYS-LYS-ARG-HIS-VAL-ILE-LYS-PRO-HIS-ILE-CYS-ARG-LYS-ILE-CYS-GLY-LYS-ASN-NH2

H-ILE-LYS-CYS-ASN-CYS-LYS-ARG-HIS-VAL-ILE-LYS-PRO-HIS-ILE-CYS-ARG-LYS-ILE-CYS-GLY-LYS-ASN-NH2 (RANDOM CYCLIZATION)

IKCNCKRHVIKPHICRKICGKN-NH2

ILE-LYS-CYS-ASN-CYS-LYS-ARG-HIS-VAL-ILE-LYS-PRO-HIS-ILE-CYS-ARG-LYS-ILE-CYS-GLY-LYS-ASN-NH2

MAST CELL DEGRANULATING PEPTIDE

MAST CELL DEGRANULATING PEPTIDE (APIS MELLIFERA)

MAST CELL DEGRANULATING (MCD) PEPTIDE

MCD PEPTIDE

MCD PEPTIDE (APIS MELLIFERA)

MCD

isulfide)

mastcelldegranulatingpeptide(honeybee)

mastcelldegranulatingpeptide(honeybeereduced)cyclic(3-15),(5-19)-bis(d

MCD-PEPTIDE (HONEYBEE, APIS MELLIFERA)

L-Ile-L-Lys-L-Cys(1)-L-Asn-L-Cys(2)-L-Lys-L-Arg-L-His-L-Val-L-Ile-L-Lys-L-Pro-L-His-L-Ile-L-Cys(1)-L-Arg-L-Lys-L-Ile-L-Cys(2)-Gly-L-Lys-L-Asn-NH2

Peptide 401

Mast Cell Degranulating (MCD) Peptide Peptide 401

L-Aspartamide, L-isoleucyl-L-lysyl-L-cysteinyl-L-asparaginyl-L-cysteinyl-L-lysyl-L-arginyl-L-histidyl-L-valyl-L-isoleucyl-L-lysyl-L-prolyl-L-histidyl-L-isoleucyl-L-cysteinyl-L-arginyl-L-lysyl-L-isoleucyl-L-cysteinylglycyl-L-lysyl-, cyclic (3→15),(5→19)-bis(disulfide)

32908-73-9

C110H192N40O24S4

Voltage-gated Ion Channels

Ion Channels

Potassium Channel Modulators

Monovalent Ion Channels

BioChemical

Cell Signaling and Neuroscience

Cell Biology

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