ChemicalBook > CAS DataBase List > ZEBULARINE
ZEBULARINE
- Product Name
- ZEBULARINE
- CAS No.
- 3690-10-6
- Chemical Name
- ZEBULARINE
- Synonyms
- NSC 309132;4-Deoyuridine;4-Deoxyuridine;Zebularine Zebularine;Zebularine (NSC309132;NSC309132;4-DEOXYURIDINE;4-Deoyuridine,Zebularine;2-Pyrimidone-1-β-D-riboside;Uridine Impurity 23 (Zebularine);Pyrimidin-2-one -D-Ribofuranoside
- CBNumber
- CB4497499
- Molecular Formula
- C9H12N2O5
- Formula Weight
- 228.2
- MOL File
- 3690-10-6.mol
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ZEBULARINE Property
- Melting point:
- 160-162?C
- Boiling point:
- 499.0±55.0 °C(Predicted)
- Density
- 1.73±0.1 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- DMSO: 16 mg/mL, soluble
- form
- solid
- pka
- 13.48±0.70(Predicted)
- color
- White
- Stability:
- Stable for 2 years from date of purchase as supplied. Solutions in DMSO or distilled water may be stored at -20° for up to 1 month.
- InChIKey
- RPQZTTQVRYEKCR-WCTZXXKLSA-N
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Safety
- WGK Germany
- 3
- RTECS
- UW7539720
- HS Code
- 2934999090
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Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H320Causes eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P330Rinse mouth.
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- 691400
- Product name
- Zebularine
- Packaging
- 10mg
- Price
- $216
- Updated
- 2024/03/01
Sigma-Aldrich
- Product number
- 691400
- Product name
- Zebularine
- Packaging
- 25mg
- Price
- $475
- Updated
- 2024/03/01
TCI Chemical
- Product number
- Z0022
- Product name
- Zebularine
- Purity
- >98.0%(HPLC)(T)
- Packaging
- 200mg
- Price
- $193
- Updated
- 2024/03/01
TCI Chemical
- Product number
- Z0022
- Product name
- Zebularine
- Purity
- >98.0%(HPLC)(T)
- Packaging
- 1g
- Price
- $571
- Updated
- 2024/03/01
Cayman Chemical
- Product number
- 10975
- Product name
- Zebularine
- Purity
- ≥98%
- Packaging
- 1mg
- Price
- $26
- Updated
- 2024/03/01
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ZEBULARINE Chemical Properties,Usage,Production
Description
Zebularine (3690-10-6) is an orally active DNA methyltransferase inhibitor. Inhibits tumor cell proliferation (IC50 = 120 μM) and re-activates silenced genes in T24 bladder carcinoma cells. Zebularine inhibits cytidine deaminase (Ki ~ 2 μM and; induces differentiation of mesenchymal stem cells into cardiomyocytes.
Chemical Properties
White Solid
Uses
It is a cytidine analogue, cytidine deaminase inhibitor, and DNA demethylating agent.
Definition
ChEBI: Zebularine is a member of pyrimidine ribonucleosides.
Biological Activity
Orally active DNA methyltransferase inhibitor. Inhibits tumor cell proliferation (IC 50 = 120 μ M) and re-activates silenced genes in T24 bladder carcinoma cells. Also inhibits cytidine deaminase (K i ~ 2 μ M).
Biochem/physiol Actions
Zebularine is a cytidine analogue, cytidine deaminase inhibitor, and DNA demethylating agent.
storage
Desiccate at RT
ZEBULARINE Preparation Products And Raw materials
Raw materials
Preparation Products
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ZEBULARINE Suppliers
- Tel
- 0371-65325800 13700860222
- haifeng.zhang@pannacean.com
- Country
- China
- ProdList
- 637
- Advantage
- 58
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- 0371-85513397 +86-18610099868;
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- China
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- 19308655899
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- -
- 2677609105@qq.com
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- China
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- 010-82848833 400-666-7788
- Fax
- 86-10-82849933
- jkinfo@jkchemical.com
- Country
- China
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- 96815
- Advantage
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- 821-50328103-801 18930552037
- Fax
- 86-21-50328109
- 3bsc@sina.com
- Country
- China
- ProdList
- 15839
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- Tel
- 021-67121386
- Fax
- 021-67121385
- Sales-CN@TCIchemicals.com
- Country
- China
- ProdList
- 24529
- Advantage
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- Tel
- 010-89508211 18501085097
- Fax
- 010-89508210
- sales.bj@hwrkchemical.com
- Country
- China
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- Tel
- 021-50135380
- shchemsky@sina.com
- Country
- China
- ProdList
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- Advantage
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- Tel
- +86 (531) 88811783
- Fax
- +86 (531) 55696010 QQ 1762738062
- sales@trio-pharmatech.com (International market)
- Country
- China
- ProdList
- 1856
- Advantage
- 62
- Tel
- +86057186818502 13588463833
- Fax
- Pls mail us for more information!
- info@sagechem.com
- Country
- China
- ProdList
- 10266
- Advantage
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View Lastest Price from ZEBULARINE manufacturers
Shaanxi Dideu Medichem Co. Ltd
- Product
- ZEBULARINE 3690-10-6
- Price
- US $1.00/Kg
- Min. Order
- 1Kg
- Purity
- 98%
- Supply Ability
- 20T
- Release date
- 2024-07-19
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