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SECO RAPAMYCIN SODIUM SALT

Product Name
SECO RAPAMYCIN SODIUM SALT
CAS No.
148554-65-8
Chemical Name
SECO RAPAMYCIN SODIUM SALT
Synonyms
Secosirolimus;Secorapamycin Na salt;SECORAPAMYCIN A MONOSODIUM;SECO RAPAMYCIN SODIUM SALT;seco Rapamycin Sodium Salt, >85% By HPLC;(19E/Z)-seco Rapamycin Sodium Salt, (>80% HPLC);(19E/Z)-seco Rapamycin Sodium Salt (~80% by HPLC)
CBNumber
CB4501000
Molecular Formula
C51H80NNaO13
Formula Weight
938.18
MOL File
148554-65-8.mol
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SECO RAPAMYCIN SODIUM SALT Property

Melting point:
120-122°C
storage temp. 
Amber Vial, -20°C Freezer, Under Inert Atmosphere
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Solid
color 
Pale Yellow to Yellow
Stability:
Light Sensitive
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
16158
Product name
Seco Rapamycin (sodium salt)
Purity
≥85%
Packaging
1mg
Price
$118
Updated
2024/03/01
Cayman Chemical
Product number
16158
Product name
Seco Rapamycin (sodium salt)
Purity
≥85%
Packaging
10mg
Price
$701
Updated
2024/03/01
Cayman Chemical
Product number
16158
Product name
Seco Rapamycin (sodium salt)
Purity
≥85%
Packaging
500μg
Price
$65
Updated
2021/12/16
Cayman Chemical
Product number
16158
Product name
Seco Rapamycin (sodium salt)
Purity
≥85%
Packaging
5mg
Price
$468
Updated
2024/03/01
TRC
Product number
R124010
Product name
(19E/Z)-secoRapamycinSodiumSalt(~80%byHPLC)
Packaging
10mg
Price
$205
Updated
2021/12/16
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SECO RAPAMYCIN SODIUM SALT Chemical Properties,Usage,Production

Description

Rapamycin is a natural macrolide immunosuppressant that activates mTORC1. Seco Rapamycin (sodium salt) is a nonenzyme-dependent degradation product of rapamycin resulting from ester hydration followed by dehydration. It has less than 4% of the potency of rapamycin in a thymocyte proliferation assay. Rapamycin quickly degrades to two ring-opened products, including seco rapamycin, in the cytoplasm or in homogenates of Caco-2 cells. Like rapamycin, seco rapamycin is secreted from cells by P-glycoprotein and metabolized to a common dihydro species. While seco rapamycin poorly activates mTOR, it mimics rapamycin in its ability to inhibit the proteasome.

Chemical Properties

Yellow Solid

Uses

A metabolite of Sirolimus

Uses

A decomposition product of Rapamycin (R124000).

SECO RAPAMYCIN SODIUM SALT Preparation Products And Raw materials

Raw materials

Preparation Products

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SECO RAPAMYCIN SODIUM SALT Suppliers

China DongFan Chemical Co.,LTD
Tel
86-0571-85151182
Fax
86-0571-85151182
Country
China
ProdList
5700
Advantage
66
BOC Sciences
Tel
1-631-485-4226; 16314854226
Email
info@bocsci.com
Country
United States
ProdList
14059
Advantage
65
MedChemexpress LLC
Tel
021-58955995
Fax
609-228-5909
Email
sales@medchemexpress.cn
Country
United States
ProdList
4863
Advantage
58
Shenzhen SUNGENING Bio-Medical Co., Ltd.
Tel
0755-28967200 13631290199
Fax
0755-28967200
Email
wxf@sungening.com
Country
China
ProdList
9506
Advantage
60
Musechem
Tel
+1-800-259-7612
Fax
+1-800-259-7612
Email
info@musechem.com
Country
United States
ProdList
4662
Advantage
60
TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
19892
Advantage
58
HANGZHOU CLAP TECHNOLOGY CO.,LTD
Tel
86-571-88216897,88216896 13588875226
Fax
86-571-88216895
Email
sales@hzclap.com
Country
CHINA
ProdList
6313
Advantage
58
DC Chemicals
Tel
021-58447131 13564518121
Email
sales@dcchemicals.com
Country
China
ProdList
9414
Advantage
58
Hefei fuya biotechnology co. LTD
Tel
18096409024
Email
sales02@foreversyn.com
Country
China
ProdList
1939
Advantage
58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.
Tel
18818260767
Fax
QQ 3610331285
Email
sales@chemegen.com
Country
China
ProdList
11289
Advantage
58

148554-65-8, SECO RAPAMYCIN SODIUM SALTRelated Search:


  • SECORAPAMYCIN A MONOSODIUM
  • seco Rapamycin Sodium Salt, >85% By HPLC
  • SECO RAPAMYCIN SODIUM SALT
  • (19E/Z)-seco Rapamycin Sodium Salt (~80% by HPLC)
  • (19E/Z)-seco Rapamycin Sodium Salt, (>80% HPLC)
  • Secorapamycin Na salt
  • Secosirolimus
  • 148554-65-8
  • C51H78NNaO13
  • Metabolites & Impurities
  • Various Metabolites and Impurities
  • Chiral Reagents
  • Heterocycles
  • Impurities
  • Intermediates & Fine Chemicals
  • Pharmaceuticals