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SECO RAPAMYCIN SODIUM SALT

Product Name
SECO RAPAMYCIN SODIUM SALT
CAS No.
148554-65-8
Chemical Name
SECO RAPAMYCIN SODIUM SALT
Synonyms
Secosirolimus;Secorapamycin Na salt;SECORAPAMYCIN A MONOSODIUM;SECO RAPAMYCIN SODIUM SALT;seco Rapamycin Sodium Salt, >85% By HPLC;(19E/Z)-seco Rapamycin Sodium Salt, (>80% HPLC);(19E/Z)-seco Rapamycin Sodium Salt (~80% by HPLC)
CBNumber
CB4501000
Molecular Formula
C51H80NNaO13
Formula Weight
938.18
MOL File
148554-65-8.mol
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SECO RAPAMYCIN SODIUM SALT Property

Melting point:
120-122°C
storage temp. 
Amber Vial, -20°C Freezer, Under Inert Atmosphere
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Solid
color 
Pale Yellow to Yellow
Stability:
Light Sensitive
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
16158
Product name
Seco Rapamycin (sodium salt)
Purity
≥85%
Packaging
1mg
Price
$118
Updated
2024/03/01
Cayman Chemical
Product number
16158
Product name
Seco Rapamycin (sodium salt)
Purity
≥85%
Packaging
10mg
Price
$701
Updated
2024/03/01
Cayman Chemical
Product number
16158
Product name
Seco Rapamycin (sodium salt)
Purity
≥85%
Packaging
500μg
Price
$65
Updated
2021/12/16
Cayman Chemical
Product number
16158
Product name
Seco Rapamycin (sodium salt)
Purity
≥85%
Packaging
5mg
Price
$468
Updated
2024/03/01
TRC
Product number
R124010
Product name
(19E/Z)-secoRapamycinSodiumSalt(~80%byHPLC)
Packaging
10mg
Price
$205
Updated
2021/12/16
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SECO RAPAMYCIN SODIUM SALT Chemical Properties,Usage,Production

Description

Rapamycin is a natural macrolide immunosuppressant that activates mTORC1. Seco Rapamycin (sodium salt) is a nonenzyme-dependent degradation product of rapamycin resulting from ester hydration followed by dehydration. It has less than 4% of the potency of rapamycin in a thymocyte proliferation assay. Rapamycin quickly degrades to two ring-opened products, including seco rapamycin, in the cytoplasm or in homogenates of Caco-2 cells. Like rapamycin, seco rapamycin is secreted from cells by P-glycoprotein and metabolized to a common dihydro species. While seco rapamycin poorly activates mTOR, it mimics rapamycin in its ability to inhibit the proteasome.

Chemical Properties

Yellow Solid

Uses

A metabolite of Sirolimus

Uses

A decomposition product of Rapamycin (R124000).

SECO RAPAMYCIN SODIUM SALT Preparation Products And Raw materials

Raw materials

Preparation Products

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SECO RAPAMYCIN SODIUM SALT Suppliers

Canada 1 China 33 India 4 United States 9 Global 47

148554-65-8, SECO RAPAMYCIN SODIUM SALTRelated Search:

Rapamycin N-DECANOYLSARCOSINE SODIUM SALT SECO RAPAMYCIN SODIUM SALT

  • SECORAPAMYCIN A MONOSODIUM
  • seco Rapamycin Sodium Salt, >85% By HPLC
  • SECO RAPAMYCIN SODIUM SALT
  • (19E/Z)-seco Rapamycin Sodium Salt (~80% by HPLC)
  • (19E/Z)-seco Rapamycin Sodium Salt, (>80% HPLC)
  • Secorapamycin Na salt
  • Secosirolimus
  • 148554-65-8
  • C51H78NNaO13
  • Metabolites & Impurities
  • Various Metabolites and Impurities
  • Chiral Reagents
  • Heterocycles
  • Impurities
  • Intermediates & Fine Chemicals
  • Pharmaceuticals