SECO RAPAMYCIN SODIUM SALT

Product Name: SECO RAPAMYCIN SODIUM SALT
CAS No.: 148554-65-8
Chemical Name: SECO RAPAMYCIN SODIUM SALT
Synonyms: Secosirolimus;Secorapamycin Na salt;SECORAPAMYCIN A MONOSODIUM;SECO RAPAMYCIN SODIUM SALT;seco Rapamycin Sodium Salt, >85% By HPLC;(19E/Z)-seco Rapamycin Sodium Salt, (>80% HPLC);(19E/Z)-seco Rapamycin Sodium Salt (~80% by HPLC)
CBNumber: CB4501000
Molecular Formula: C51H80NNaO13
Formula Weight: 938.18
MOL File: 148554-65-8.mol

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SECO RAPAMYCIN SODIUM SALT Property

Melting point:: 120-122°C
storage temp.: Amber Vial, -20°C Freezer, Under Inert Atmosphere
solubility: DMSO (Slightly), Methanol (Slightly)
form: Solid
color: Pale Yellow to Yellow
Stability:: Light Sensitive

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 16158
Product name: Seco Rapamycin (sodium salt)
Purity: ≥85%
Packaging: 1mg
Price: $118
Updated: 2024/03/01

Cayman Chemical

Product number: 16158
Product name: Seco Rapamycin (sodium salt)
Purity: ≥85%
Packaging: 10mg
Price: $701
Updated: 2024/03/01

Cayman Chemical

Product number: 16158
Product name: Seco Rapamycin (sodium salt)
Purity: ≥85%
Packaging: 500μg
Price: $65
Updated: 2021/12/16

Cayman Chemical

Product number: 16158
Product name: Seco Rapamycin (sodium salt)
Purity: ≥85%
Packaging: 5mg
Price: $468
Updated: 2024/03/01

TRC

Product number: R124010
Product name: (19E/Z)-secoRapamycinSodiumSalt(~80%byHPLC)
Packaging: 10mg
Price: $205
Updated: 2021/12/16

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SECO RAPAMYCIN SODIUM SALT Chemical Properties,Usage,Production

Description

Rapamycin is a natural macrolide immunosuppressant that activates mTORC1. Seco Rapamycin (sodium salt) is a nonenzyme-dependent degradation product of rapamycin resulting from ester hydration followed by dehydration. It has less than 4% of the potency of rapamycin in a thymocyte proliferation assay. Rapamycin quickly degrades to two ring-opened products, including seco rapamycin, in the cytoplasm or in homogenates of Caco-2 cells. Like rapamycin, seco rapamycin is secreted from cells by P-glycoprotein and metabolized to a common dihydro species. While seco rapamycin poorly activates mTOR, it mimics rapamycin in its ability to inhibit the proteasome.

Chemical Properties

Yellow Solid

Uses

A metabolite of Sirolimus

Uses

A decomposition product of Rapamycin (R124000).

SECO RAPAMYCIN SODIUM SALT Preparation Products And Raw materials

Raw materials

Preparation Products

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SECO RAPAMYCIN SODIUM SALT Suppliers

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148554-65-8, SECO RAPAMYCIN SODIUM SALTRelated Search:

Rapamycin N-DECANOYLSARCOSINE SODIUM SALT SECO RAPAMYCIN SODIUM SALT

SECORAPAMYCIN A MONOSODIUM

seco Rapamycin Sodium Salt, >85% By HPLC

SECO RAPAMYCIN SODIUM SALT

(19E/Z)-seco Rapamycin Sodium Salt (~80% by HPLC)

(19E/Z)-seco Rapamycin Sodium Salt, (>80% HPLC)

Secorapamycin Na salt

Secosirolimus

148554-65-8

C51H78NNaO13

Metabolites & Impurities

Various Metabolites and Impurities

Chiral Reagents

Heterocycles

Impurities

Intermediates & Fine Chemicals

Pharmaceuticals