ChemicalBook > CAS DataBase List > OLOMOUCINE II
OLOMOUCINE II
- Product Name
- OLOMOUCINE II
- CAS No.
- 500735-47-7
- Chemical Name
- OLOMOUCINE II
- Synonyms
- Nsc736738;Olomoucine II - CAS 500735-47-7 - Calbiochem;Olomoucine ii, 6-[(2-hydroxybenzyl)amino]-2-[1-(hydroxymethyl)propylamino]- 9-isopropylpurine;2-[[[2-[[(1R)-1-(Hydroxymethyl)propyl]amino]-9-(1-methylethyl)-9H-purin-6-yl]amino]methyl]phenol;Phenol, 2-[[[2-[[(1R)-1-(hydroxymethyl)propyl]amino]-9-(1-methylethyl)-9H-purin-6-yl]amino]methyl]-
- CBNumber
- CB4504061
- Molecular Formula
- C19H26N6O2
- Formula Weight
- 370.45
- MOL File
- 500735-47-7.mol
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OLOMOUCINE II Property
- Boiling point:
- 618.5±65.0 °C(Predicted)
- Density
- 1.32
- storage temp.
- −20°C
- solubility
- chloroform: 50 mg/mL, soluble
- form
- powder
- pka
- 9.83±0.30(Predicted)
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Safety
- Safety Statements
- 22-24/25
- WGK Germany
- 3
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- 495621
- Product name
- Olomoucine II
- Packaging
- 5mg
- Price
- $308
- Updated
- 2023/01/07
American Custom Chemicals Corporation
- Product number
- API0008354
- Product name
- OLOMOUCINE II
- Purity
- 95.00%
- Packaging
- 1MG
- Price
- $144.9
- Updated
- 2021/12/16
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OLOMOUCINE II Chemical Properties,Usage,Production
Definition
ChEBI: 2-[[[2-(1-hydroxybutan-2-ylamino)-9-propan-2-yl-6-purinyl]amino]methyl]phenol is a thiopurine.
General Description
A cell-permeable 2,6,9-trisubstituted purine analog that acts as a potent, reversible, and ATP-competitive inhibitor of Cdk1/B with an IC50 of 20 nM and displays increased potency over purvalanol A (Cat. No. 540500; IC50 = 50 nM), Roscovitine (Cat. No. 557360; IC50 = 450 nM), Bohemine (Cat. No. 203600; IC50 = 1.1 μM) and Olomoucine (Cat. No. 495620; IC50 = 7.0 μM). Further, exerts greater in vitro cytotoxicity in various cancer cell lines (IC50 = 3.0 μM, 5.3 μM, 6.3 μM, 6.3 μM and 11.1 μM for CEM, MCF7, HOS, G631 and K562, respectively).
Biochem/physiol Actions
Cell permeable: yes
OLOMOUCINE II Preparation Products And Raw materials
Raw materials
Preparation Products
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OLOMOUCINE II Suppliers
- Tel
- 021-61415566 800-8193336
- orderCN@merckgroup.com
- Country
- China
- ProdList
- 51456
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- 80
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- 021-65675885 18964387627
- Fax
- 021-65675885
- info@efebio.com
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- China
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- Tel
- 18818260767
- Fax
- QQ 3610331285
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- Country
- China
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- Tel
- 4008200310
- marketing@tsbiochem.com
- Country
- China
- ProdList
- 24647
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- Tel
- +1-+1(833)-552-7181
- sales@aladdinsci.com
- Country
- United States
- ProdList
- 52925
- Advantage
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500735-47-7, OLOMOUCINE IIRelated Search:
Ro 3306
N9-ISOPROPYL-OLOMOUCINE
(S)-ROSCOVITINE
NU6140
3-amino-10H-acridine-9-thione
ARCYRIAFLAVIN A
PURVALANOL A
2(BIS-(HYDROXYETHYL)AMINO)-6-(4-METHOXYBENZYLAMINO)-9-ISOPROPYL-PURINE
AMINOPURVALANOL A
SU 9516
NU6102
OLOMOUCINE