ChemicalBook > CAS DataBase List > 1,4-dihydroxy-2naphthoic acid methyl ester

1,4-dihydroxy-2naphthoic acid methyl ester

Product Name
1,4-dihydroxy-2naphthoic acid methyl ester
CAS No.
77060-74-3
Chemical Name
1,4-dihydroxy-2naphthoic acid methyl ester
Synonyms
Methyl 1,4-dihydroxy-2-phthoate;METHYL-1,4-DIHYDROXY-2-NAPHTHOATE;1,4-Dihydroxy-2-naphthoic acid methylester;1,4-Dihydroxy-2-naphthalenecarboxylic acid methyl ester;2-Naphthalenecarboxylic acid, 1,4-dihydroxy-, methyl ester
CBNumber
CB4511614
Molecular Formula
C12H10O4
Formula Weight
218.21
MOL File
77060-74-3.mol
More
Less

1,4-dihydroxy-2naphthoic acid methyl ester Property

Melting point:
192-193 ºC
Boiling point:
432.9±25.0 °C(Predicted)
Density 
1.378
storage temp. 
2-8°C
pka
8.77±0.50(Predicted)
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

More
Less

N-Bromosuccinimide Price

American Custom Chemicals Corporation
Product number
CHM0987545
Product name
1,4-DIHYDROXY-2-NAPHTHALENECARBOXYLIC ACID METHYL ESTER
Purity
95.00%
Packaging
5MG
Price
$504.09
Updated
2021/12/16
Chemenu
Product number
CM128377
Product name
methyl1,4-dihydroxy-2-naphthoate
Purity
95%
Packaging
1g
Price
$333
Updated
2021/12/16
Crysdot
Product number
CD41000402
Product name
Methyl1,4-dihydroxy-2-naphthoate
Purity
95+%
Packaging
1g
Price
$356
Updated
2021/12/16
Alichem
Product number
77060743
Product name
Methyl1,4-dihydroxy-2-naphthoate
Packaging
5g
Price
$391.02
Updated
2021/12/16
More
Less

1,4-dihydroxy-2naphthoic acid methyl ester Chemical Properties,Usage,Production

Uses

1,4-dihydroxy-2naphthoic acid methyl ester can be used as organic synthesis intermediate and pharmaceutical intermediate, mainly used in laboratory research and development process and chemical production process.

Synthesis


To a stirred solution of LiOt-Bu (3.20 mmol) in THF (10 mL) at -78 ??C(CHCl3-liq N2 bath) under an inert atmosphere was added a solutionof isocyanophthalide (1.0 mmol) in THF (5 mL). The resulting yellowish solution was stirred at -78 ??C for 25 min, after which a solution of a Michael acceptor (1.0-1.5 equiv unless otherwise stated) in THF (5mL) was added. The cooling bath was removed after ca. 1 h at -78 ??C and the mixture was brought to r.t. over a period of 1 h and stirred fora further 2-6 h. The reaction was then quenched with 10% aq NH4Cl(15 mL) and the resulting solution was concentrated. The residue was diluted with EtOAc (50 mL) and the layers were separated. The aqueous layer was extracted with EtOAc (3 ?á 25 mL). The combined extracts were washed with H2O (15 mL) and brine (15 mL), dried (anhydNa2SO4), and concentrated under reduced pressure. The crude product was purified by column chromatography (silica gel) or by recrystallizationto obtain the pure product.

1,4-dihydroxy-2naphthoic acid methyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

1,4-dihydroxy-2naphthoic acid methyl ester Suppliers

China 70 Germany 1 Slovakia 1 United States 6 Global 78
Shijiazhuang Sdyano Fine Chemical Co., Ltd.
Tel
0311-89250318 031166536426
Fax
4000311741
Email
master@sjzsdyn.com
Country
China
ProdList
2882
Advantage
65
T&W GROUP
Tel
021-61551611 13296011611
Fax
＋86 21-50676805
Email
contact@trustwe.com
Country
China
ProdList
9900
Advantage
58
Shanghai Arbor Chemical Co., Ltd.
Tel
021-021-60451683 15021268886
Fax
+86-21-60451682
Email
sales@arborchemical.com
Country
China
ProdList
922
Advantage
55
Bide Pharmatech Ltd.
Tel
400-1647117 15221909166
Fax
+86-21-61629029
Email
product02@bidepharm.com
Country
China
ProdList
41438
Advantage
60
Hunan HuaTeng Pharmaceutical Co., Ltd.,
Tel
400-8592883 15367835770
Fax
0731-82251112
Email
viola@huatengsci.com
Country
China
ProdList
5877
Advantage
58
Shanghai QianJin Chemical Technology Co., Ltd
Tel
021-20900665 17321230821
Fax
021-20900665
Email
2986274987@qq.com
Country
China
ProdList
982
Advantage
55
Shanghai Yongye Biotechnology Co., Ltd.
Tel
86-021-61559134 15921386130
Fax
021-55068248
Email
3423497944@qq.com
Country
China
ProdList
8147
Advantage
55
Nanjing Duolong Bio-tech Co.,Ltd.
Tel
18905173768
Fax
025-83263139
Email
sales@dolonchem.com
Country
China
ProdList
2297
Advantage
50
Nanjing Chalf-Pharm Technology Co., Ltd.
Tel
025-57018978 18251899859
Fax
025-57018008
Email
sales@chalf-pharm.com
Country
China
ProdList
5943
Advantage
50
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
Tel
025-66113011 18112977050
Email
cb6@aikonchem.com
Country
China
ProdList
16687
Advantage
50
Credit Asia Chemical Co., Ltd.
Tel
+86 (21) 61124340
Fax
+86 (21) 6129-4103
Country
China
ProdList
9767
Advantage
58
Watson Biotechnology Co.,Ltd
Tel
027-027-59207879 18140587686
Fax
QQ：1972026995
Email
kf@3600chem.com
Country
China
ProdList
4697
Advantage
55
Henan CoreyChem Co., Ltd
Tel
0371-86658258
Fax
0371-60996044
Email
info@coreychem.com
Country
China
ProdList
10457
Advantage
58
Zhengzhou Alfachem Co.,Ltd.
Tel
0371-53778726 18003825608
Fax
QQ：2885354392
Email
liuxiaoyan@alfachem.cn
Country
China
ProdList
1951
Advantage
58
Shijiazhuang Sdyano Fine Chemical Co., Ltd.
Tel
0311-89250318 031166536426
Fax
4000311741
Email
master@sjzsdyn.com
Country
China
ProdList
3496
Advantage
58
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
27322
Advantage
60
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131981
Advantage
58
Wuhan FengyaoTonghui Chemical Products Co., Ltd.
Tel
027-87466105 15377573527
Email
2678564200@qq.com
Country
China
ProdList
17997
Advantage
58
Tianjin heowns Biochemical Technology Co., Ltd.
Tel
400-6387771-6038 18902104717
Email
sales@heowns.com
Country
China
ProdList
20532
Advantage
60
Nanjing crow LuNing pharmaceutical technology co., LTD
Tel
13382066392
Country
CHINA
ProdList
4880
Advantage
58
Shanghai Jizhi Biochemical Technology Co. Ltd.
Tel
400-400-400-9004166 18616739031
Email
3007523370@qq.com
Country
China
ProdList
52712
Advantage
58
Guangdong wengjiang Chemical Reagent Co., Ltd.
Tel
0751-2815688 13927872512
Fax
0751-8963795
Email
3007421951@qq.com
Country
China
ProdList
10067
Advantage
58
Beijing Minruida Technology Co., Ltd.
Tel
010-82387566 18001021521;
Fax
82387566-801
Email
sales@mreda.com.cn
Country
China
ProdList
21450
Advantage
58
Hefei TNJ Chemical Industry Co.,Ltd.
Tel
0551-65418684 +8618949823763
Fax
0086-551-65418684
Email
sales@tnjchem.com
Country
China
ProdList
25363
Advantage
58
CD Chemical Group Limited
Tel
+8615986615575
Fax
0086-13651442114
Email
info@codchem.com
Country
China
ProdList
20356
Advantage
58
Dayang Chem (Hangzhou) Co.,Ltd.
Tel
571-88938639 +8617705817739
Fax
+86-571-88938652，+86-571- 88492614
Email
info@dycnchem.com
Country
CHINA
ProdList
52867
Advantage
58
AFINE CHEMICALS LIMITED
Tel
0571-85134551 18958018566;
Fax
008657185134895
Email
info@afinechem.com
Country
China
ProdList
15377
Advantage
58
ZHEJIANG CHEMPACIFIC CHEMICAL CO.,LTD
Tel
+86-13586356488 13586348435
Fax
+86-0573-85576068
Email
sales@chempacific.com
Country
CHINA
ProdList
88
Advantage
58
Shanghai Yanze Chemical Co., Ltd.
Tel
021-13773155751 19901447308
Email
260924549@qq.com
Country
China
ProdList
8709
Advantage
58
Chongqing Chemdad Co., Ltd
Tel
+86-023-61398051 +8613650506873
Email
sales@chemdad.com
Country
China
ProdList
39916
Advantage
58
Wuhan Yuqing Jiaheng Pharmaceutical Co., Ltd
Tel
027-83855382 15926260338
Email
15926260338@163.com
Country
China
ProdList
2041
Advantage
58
Wuhan hongde yuexin pharmaceutical technology co. LTD
Tel
027-83855391 13657260109
Fax
027-83855391
Email
hbzlkschem2009@163.com
Country
China
ProdList
3055
Advantage
58
career henan chemical co
Tel
+86-0371-86658258 15093356674;
Fax
0086-371-86658258
Email
factory@coreychem.com
Country
China
ProdList
29826
Advantage
58
Shaanxi Dideu Medichem Co. Ltd
Tel
+86-029-81148696 +8615536356810
Email
1047@dideu.com
Country
China
ProdList
2694
Advantage
58
Shanghai Haohong Pharmaceutical Co., Ltd.
Tel
4008210725 4008210725
Email
malulu@leyan.com
Country
China
ProdList
55023
Advantage
58
Zhongxin Chenshi (Wuhan) Technology Co., Ltd
Tel
18942922096
Fax
QQ 2662561040
Email
2662561040@qq.com
Country
China
ProdList
1002
Advantage
58
CHANGZHOU GARDE PHARMTECH CO.,LTD
Tel
13921092594
Email
gardepharm@163.com
Country
China
ProdList
170
Advantage
58
TCI (Shanghai) Chemical Trading Co., Ltd.
Tel
021-61109150
Fax
021-61105897
Email
sales@tcisct.com
Country
China
ProdList
31163
Advantage
58
JinOu Biomedical (Nanjing) Co., Ltd.
Tel
13000000000
Fax
jinoupharma@163
Email
jinoupharma@163.com
Country
China
ProdList
11732
Advantage
58
Bide Pharmatech Ltd.
Tel
400-6005915
Email
sales@picasso-e.com
Country
China
ProdList
39661
Advantage
58
Shaanxi DIDU pharmaceutical and Chemical Co., Ltd
Tel
17691182729 18161915376
Email
1046@dideu.com
Country
China
ProdList
10010
Advantage
58
Shanghai Maclean Biochemical Technology Co., LTD
Tel
021-50706066 15221275939
Email
shenlinxing@macklin.cn
Country
China
ProdList
29803
Advantage
58
Suzhou Daolan Biomedical Technology Co., Ltd.
Tel
13771737464
Email
sales@dolanchem.com
Country
China
ProdList
2783
Advantage
58
Tangyuan Life Science (Shanghai) Co., Ltd
Tel
400-618-1121
Fax
400-618-1121
Email
sales@townyuan.com
Country
China
ProdList
2984
Advantage
58
Wuhan Fengyao Tonghui Chemical Products Co. LTD
Tel
027-87466205 15377579727
Email
1228964013@qq.com
Country
China
ProdList
8561
Advantage
58
Shanghai Jianchao Biotechnology Co., LTD
Tel
13621743886 13621743886
Email
3366408901@qq.com
Country
China
ProdList
3821
Advantage
58
Beijing Solarbio Science & Tecnology Co., Ltd.
Tel
010-50973130 17801761073
Email
Gsiyu@solarbio.com
Country
China
ProdList
50471
Advantage
58
Shanghai Jieshikai Biotechnology Co. , Ltd.
Tel
021-57520305 13764600721
Email
wangkang@jskchem.com
Country
China
ProdList
49036
Advantage
58
Hangzhou Xiao Bei Medical Technology Co., LTD
Tel
+86-571-8526 3177 13962438025
Email
beixi.dong@heryipharma.com
Country
China
ProdList
163
Advantage
58
Nantong Zhonghe Chemical New Materials Co., Ltd
Tel
13003551299 13003551299
Email
2369399482@qq.com
Country
China
ProdList
7568
Advantage
58
More
Less

View Lastest Price from 1,4-dihydroxy-2naphthoic acid methyl ester manufacturers

Shaanxi Dideu Medichem Co. Ltd
Product
Methyl 1,4-dihydroxy-2-naphthoate 77060-74-3
Price
US $0.10/KG
Min. Order
1KG
Purity
99.0%
Supply Ability
1000 tons
Release date
2020-04-24
Shaanxi Dideu Medichem Co. Ltd
Product
Methyl 1,4-dihydroxy-2- naphthoate 77060-74-3
Price
US $0.00-0.00/Kg
Min. Order
1KG
Purity
99.0%+
Supply Ability
100 tons
Release date
2020-01-15
Career Henan Chemical Co
Product
Methyl 1,4-dihydroxy-2-naphthoate 77060-74-3
Price
US $9.80/KG
Min. Order
1g
Purity
≥99%
Supply Ability
100kg
Release date
2020-01-08

77060-74-3, 1,4-dihydroxy-2naphthoic acid methyl esterRelated Search:

Tribenuron methyl Methyl benzoylformate 1,4-Dihydroxy-2-naphthoic acid Kresoxim-methyl Methyl salicylate Methyl carbamate Methyl acrylate Methyl 3,4-dihydroxybenzoate Basic Violet 1 Methyl 2-bromobenzoate Methyl anthranilate Methylparaben Methyl formate Methyl benzoate Methanol METSULFURON METHYL 2-Naphthoic acid Methyl

  • Methyl 1,4-dihydroxy-2-phthoate
  • METHYL-1,4-DIHYDROXY-2-NAPHTHOATE
  • 1,4-Dihydroxy-2-naphthoic acid methylester
  • 1,4-Dihydroxy-2-naphthalenecarboxylic acid methyl ester
  • 2-Naphthalenecarboxylic acid, 1,4-dihydroxy-, methyl ester
  • 77060-74-3