1-BOC-AMINO-2,2-DIMETHYL-1,3-PROPANEDIAMINE

Product Name: 1-BOC-AMINO-2,2-DIMETHYL-1,3-PROPANEDIAMINE
CAS No.: 292606-35-0
Chemical Name: 1-BOC-AMINO-2,2-DIMETHYL-1,3-PROPANEDIAMINE
Synonyms: N-Boc-2,2-dimethyl-1,3-propanediamine;N-Boc-2,2-dimethyl-1,3-diaminopropane;BOC-1-AMINO-2,2-DIMETHYL-1,3-PROPYLDIAMINE;1-BOC-AMINO-2,2-DIMETHYL-1,3-PROPANEDIAMINE;tert-Butyl (3-Amino-2,2-dimethylpropyl)carbamate;tert-Butyl N-(3-amino-2,2-dimethylpropyl)carbamate;(S)-(+)-5-1-Boc-amino-2,2-dimethyl-1,3-propanediamine;N-(tert-Butoxycarbonyl)-2,2-dimethyl-1,3-propanediamine;(3-Amino-2,2-dimethylpropyl)carbamic Acid tert-Butyl Ester;N-(tert-Butoxycarbonyl)-2,2-dimethyl-1,3-propanediamine >
CBNumber: CB4666820
Molecular Formula: C10H22N2O2
Formula Weight: 202.29
MOL File: 292606-35-0.mol

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1-BOC-AMINO-2,2-DIMETHYL-1,3-PROPANEDIAMINE Property

Melting point:: 74 °C
Boiling point:: 293.8±23.0 °C(Predicted)
Density: 0.964±0.06 g/cm3(Predicted)
storage temp.: 2-8°C, protect from light
pka: 12.86±0.46(Predicted)
form: powder to crystal
color: White to Almost white
CAS DataBase Reference: 292606-35-0(CAS DataBase Reference)

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Safety

Hazard Codes: Xn
Risk Statements: 22
HS Code: 2924.19.8000

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

TCI Chemical

Product number: B3052
Product name: N-(tert-Butoxycarbonyl)-2,2-dimethyl-1,3-propanediamine
Purity: >98.0%(GC)(T)
Packaging: 1g
Price: $51
Updated: 2025/07/31

TCI Chemical

Product number: B3052
Product name: N-(tert-Butoxycarbonyl)-2,2-dimethyl-1,3-propanediamine
Purity: >98.0%(GC)(T)
Packaging: 5g
Price: $248
Updated: 2025/07/31

TRC

Product number: B789250
Product name: tert-Butyl(3-Amino-2,2-dimethylpropyl)carbamate
Packaging: 100mg
Price: $60
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB149670
Product name: 1-Boc-amino-2,2-dimethyl-1,3-propanediamine
Packaging: 250mg
Price: $85
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB149670
Product name: 1-Boc-amino-2,2-dimethyl-1,3-propanediamine
Packaging: 1g
Price: $259
Updated: 2021/12/16

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1-BOC-AMINO-2,2-DIMETHYL-1,3-PROPANEDIAMINE Chemical Properties,Usage,Production

Synthesis

7328-91-8

24424-99-5

292606-35-0

Di-tert-butyl dicarbonate was slowly added to a solution of 2,2-dimethylpropane-1,3-diamine in dichloromethane (DCM) (500 mL) of 2,2-dimethylpropane-1,3-diamine (80 g, 783 mmol) and di-tert-butyl dicarbonate (91 mL, 391 mmol) at 0 °C. The reaction mixture was stirred at ambient temperature for 12 hours. Subsequently, the reaction mixture was concentrated to remove the solvent. The crude product was purified by column chromatography (neutral alumina) using methanol: dichloromethane (1:9) as eluent to afford tert-butyl (3-amino-2,2-dimethylpropyl)carbamate (50 g, 247 mmol, 31.6% yield) as a white solid. The structure of the product was confirmed by 1H NMR (400 MHz, CDCl3): δ 0.85 (s, 6H), 1.44 (s, 9H), 2.35-2.52 (m, 2H), 3.00 (br d, J = 6.14Hz, 2H), 5.16 (br s, 1H).

References

[1] Patent: WO2018/109648, 2018, A1. Location in patent: Page/Page column 64
[2] Journal of Medicinal Chemistry, 1998, vol. 41, # 2, p. 236 - 246
[3] Patent: US2005/20623, 2005, A1. Location in patent: Page 116
[4] Patent: EP1550657, 2005, A1. Location in patent: Page/Page column 46

1-BOC-AMINO-2,2-DIMETHYL-1,3-PROPANEDIAMINE Preparation Products And Raw materials

Raw materials

Preparation Products

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1-BOC-AMINO-2,2-DIMETHYL-1,3-PROPANEDIAMINE Suppliers

Americas 1 China 72 Europe 2 France 1 Germany 1 India 2 Japan 1 United Kingdom 5 United States 12 Global 97

Alchem Pharmtech,Inc.

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ASDI Incorporated

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View Lastest Price from 1-BOC-AMINO-2,2-DIMETHYL-1,3-PROPANEDIAMINE manufacturers

Career Henan Chemical Co

Product: tert-Butyl (3-amino-2,2-dimethylpropyl)carbamate 292606-35-0
Price: US $1.00/g
Min. Order: 1g
Purity: Min98% HPLC
Supply Ability: g/kg/ton
Release date: 2020-01-07

292606-35-0, 1-BOC-AMINO-2,2-DIMETHYL-1,3-PROPANEDIAMINERelated Search:

1-BOC-AMINO-2,2-DIMETHYL-1,3-PROPANEDIAMINE tert-Butyl 2,6-diazaspiro[3.5]nonane-6-carboxylate 2,7-DIAZA-SPIRO[4.4]NONANE-2-CARBOXYLIC ACID TERT-BUTYL ESTER Carbamic acid, (7S)-5-azaspiro[2.4]hept-7-yl-, 1,1-dimethylethyl ester (9CI) 2,2-DIMETHYL-1,3-PROPANEDIAMINE TERT-BUTYL 2,7-DIAZASPIRO[4.5]DECANE-2-CARBOXYLATE 2,7-DIAZASPIRO[4.5]DECANE-7-CARBOXYLIC ACID T-BUTYL ESTER Carbamic acid, (3-azabicyclo[3.1.0]hex-1-ylmethyl)-, 1,1-dimethylethyl ester Carbamic acid, 5-azaspiro[2.4]hept-1-yl-, 1,1-dimethylethyl ester (9CI) Tert-butyl 2,6-diazaspiro[3.4]octane-2-carboxylate TERT-BUTYL 2,8-DIAZASPIRO[5.5]UNDECANE-2-CARBOXYLATE 2-OXO-1,2-DIHYDRO-SPIRO[INDOLE-3,3'-PYRROLIDINE]-1'-CARBOXYLIC ACID TERT-BUTYL ESTER Tert-butyl 2,6-diazaspiro[3.4]octane-6-carboxylate TERT-BUTYL 4-[(2-METHOXYETHYL)AMINO]-3,3-DIMETHYLPIPERIDINE-1-CARBOXYLATE 3-[N-(4-AMINO)BENZYL-2-PYRROLIDINONE]-3'-N-BOC-SPIRO-PIPERIDINE (1-IMIDAZOL-1-YLMETHYL-CYCLOPROPYLMETHYL)-CARBAMIC ACID TERT-BUTYL ESTER 3-[N-(2-AMINO)BENZYL-2-PYRROLIDINONE]-3'-N-BOC-SPIRO-PIPERIDINE 3-[N-(3-AMINO)BENZYL-2-PYRROLIDINONE]-3'-N-BOC-SPIRO-PIPERIDINE

tert-Butyl N-(3-amino-2,2-dimethylpropyl)carbamate

N-Boc-2,2-dimethyl-1,3-diaminopropane

CarbaMic acid, N-(3-aMino-2,2-diMethylpropyl)-, 1,1-diMethylethyl ester

N-Boc-2,2-dimethyl-1,3-propanediamine tert-Butyl (3-Amino-2,2-dimethylpropyl)carbamate (3-Amino-2,2-dimethylpropyl)carbamic Acid tert-Butyl Ester N-Boc-2,2-dimethyl-1,3-diaminopropane

<i>N</i>-(<i>tert</i>-Butoxycarbonyl)-2,2-dimethyl-1,3-propanediamine

1-BOC-AMINO-2,2-DIMETHYL-1,3-PROPANEDIAMINE

BOC-1-AMINO-2,2-DIMETHYL-1,3-PROPYLDIAMINE

(3-Amino-2,2-dimethylpropyl)carbamic Acid tert-Butyl Ester

N-(tert-Butoxycarbonyl)-2,2-dimethyl-1,3-propanediamine

N-Boc-2,2-dimethyl-1,3-propanediamine

tert-Butyl (3-Amino-2,2-dimethylpropyl)carbamate

Carbamic acid, (3-amino-2,2-dimethylpropyl)-, 1,1-dimethylethyl ester (9CI)

(S)-(+)-5-1-Boc-amino-2,2-dimethyl-1,3-propanediamine

N-(tert-Butoxycarbonyl)-2,2-dimethyl-1,3-propanediamine &gt

292606-35-0

AMIDE

Monoprotected Diaminoalkanes

N-Boc-diaminoalkanes

N-BOC

pharmacetical