ChemicalBook > CAS DataBase List > (E,E)-Farnesol

(E,E)-Farnesol

Product Name
(E,E)-Farnesol
CAS No.
106-28-5
Chemical Name
(E,E)-Farnesol
Synonyms
trans-Farnesol;(2E,6E)-Farnesol;TRANS,TRANS-FARNESOL;(2E,6E)-3,7,11-Trimethyl-2,6,10-dodecatrien-1-ol;FEMA 2478;3,7,11-TRIMETHYLDODECA-2,6,10-TRIEN-1-OL;(E)-farnesol;Inhibitor A2;(E,E)-FARNESOL;all-E-Farnesol
CBNumber
CB4669245
Molecular Formula
C15H26O
Formula Weight
222.37
MOL File
106-28-5.mol
More
Less

(E,E)-Farnesol Property

Melting point:
61-63 °C
Boiling point:
149 °C4 mm Hg(lit.)
Density 
0.886 g/mL at 20 °C(lit.)
refractive index 
n20/D 1.490(lit.)
Flash point:
205 °F
storage temp. 
Sealed in dry,2-8°C
solubility 
Chloroform (Sparingly), DMSO (Slightly) Ethyl Acetate (Slightly)
pka
14.42±0.10(Predicted)
form 
Liquid
color 
Colourless
Odor
at 100.00 %. mild muguet floral sweet lily waxy
Odor Type
floral
Water Solubility 
Miscible with alcohol. Immiscible with water.
Sensitive 
Light Sensitive
BRN 
1723039
Stability:
Light Sensitive
InChIKey
CRDAMVZIKSXKFV-YFVJMOTDSA-N
LogP
5.31
CAS DataBase Reference
106-28-5(CAS DataBase Reference)
NIST Chemistry Reference
2,6,10-Dodecatrien-1-ol, 3,7,11-trimethyl-, (E,E)-(106-28-5)
EPA Substance Registry System
(E,E)-Farnesol (106-28-5)
More
Less

Safety

Hazard Codes 
Xi
Risk Statements 
43
Safety Statements 
24/25-36/37
WGK Germany 
3
RTECS 
JR4979000
8
TSCA 
Yes
HS Code 
29052290
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H317May cause an allergic skin reaction

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P272Contaminated work clothing should not be allowed out of the workplace.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P333+P313IF SKIN irritation or rash occurs: Get medical advice/attention.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
277541
Product name
trans,trans-Farnesol
Purity
96%
Packaging
1g
Price
$40.6
Updated
2024/03/01
Sigma-Aldrich
Product number
277541
Product name
trans,trans-Farnesol
Purity
96%
Packaging
10g
Price
$216
Updated
2024/03/01
Alfa Aesar
Product number
L14348
Product name
trans,trans-Farnesol
Purity
97%
Packaging
1g
Price
$22.65
Updated
2024/03/01
Alfa Aesar
Product number
L14348
Product name
trans,trans-Farnesol
Purity
97%
Packaging
5g
Price
$103
Updated
2024/03/01
Sigma-Aldrich
Product number
92386
Product name
trans,trans-Farnesol
Purity
AldrichCPR
Packaging
100mg
Price
$88.3
Updated
2022/05/15
More
Less

(E,E)-Farnesol Chemical Properties,Usage,Production

Description

Farnesol is widely present in the flowers, leaves, stems and other parts of plants, especially in some Chinese herbal medicine plants and spice plants with a high content, such as Cinnamomum chinensis, Pinellia sinensis, loquat leaves, etc., which are well developed and utilized An important resource for prospects. Farnesol is one of the important active components of Chinese herbal medicine plants, and also one of the main fragrance components of some important essential oils of spice plants. Therefore, it has been widely used in medicine, pesticides, cosmetics and daily chemicals that require its biological activity.

Chemical Properties

Clear Colourless Oil

Uses

trans,trans-Farnesol is an intermediate used in the biological synthesis of cholesterol from mevalonic acid. It is used in the perfume industry. Further, it is used in the preparation of terpenes such as squalenes, cembranoids and forskolin. It is also used in the synthesis of Cecropia juvenile hormone.

Uses

Farnesol is a natural organic compound which is present in many essential oils.

Definition

ChEBI: Farnesol is a farnesane sesquiterpenoid that is dodeca-2,6,10-triene substituted by methyl groups at positions 3, 7 and 11 and a hydroxy group at position 1. It has a role as a plant metabolite, a fungal metabolite and an antimicrobial agent. It is a farnesane sesquiterpenoid, a primary alcohol and a polyprenol.

Synthesis Reference(s)

Journal of the American Chemical Society, 102, p. 3298, 1980 DOI: 10.1021/ja00529a091
The Journal of Organic Chemistry, 40, p. 3617, 1975 DOI: 10.1021/jo00912a039

General Description

trans,trans-Farnesol is sesquiterpene alcohol, which is commonly found in many essential oils, citrus fruits, propolis, and plant-derived foods and beverages. It is an effective bioactive agent that can be used in pharmaceuticals and cosmetics.

Purification Methods

The main impurity is the cis-trans isomer. Purify it by gas chromatography using a 4ft x 0.125in 3%OV-1 column at 150o. [Corey et al. J Am Chem Soc 92 6637 1970, Popjak et al. J Biol Chem 237 56 1962.] It has also been fractionated through a 14-in Podbielniak column (p 11) at 11o/0.35mm. Alternatively it has been purified by gas chromatography using SF96 silicone on Fluoropak columns or Carbowax 20M on Fluoropak or base-washed 30:60 firebrick (to avoid decomposition, prepared by treating the firebrick with 5N NaOH in MeOH and washed with MeOH to pH 8) at 210o with Helium carrier gas at 60 mL/min flow rate. The diphenylcarbamoyl derivative has m 61-63o (from MeOH) and has an IR band at 3500 cm-1. [Bates et al. J Org Chem 28 1086 1963, Beilstein 1 IV 2335.]

(E,E)-Farnesol Preparation Products And Raw materials

Raw materials

Preparation Products

More
Less

(E,E)-Farnesol Suppliers

Eurolabs Limited
Tel
--
Fax
--
Country
United Kingdom
ProdList
6309
Advantage
46
Apollo Scientific Ltd.
Tel
--
Fax
--
Email
sales@apolloscientific.co.uk
Country
United Kingdom
ProdList
6084
Advantage
88
MDA Chemicals Ltd.
Tel
--
Fax
--
Email
sheila@mda-chem.co.uk
Country
United Kingdom
ProdList
1961
Advantage
30
Zerenex Molecular Limited
Tel
--
Fax
--
Email
sales@zerenex-molecular.com
Country
United Kingdom
ProdList
6204
Advantage
47
More
Less

View Lastest Price from (E,E)-Farnesol manufacturers

Hebei Zhuanglai Chemical Trading Co.,Ltd
Product
Farnesen Farnesol 106-28-5
Price
US $180.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20ton
Release date
2024-06-03
WUHAN FORTUNA CHEMICAL CO., LTD
Product
(E,E)-Farnesol 106-28-5
Price
US $0.00-0.00/Kg/Drum
Min. Order
1KG
Purity
98%min
Supply Ability
1000kg/month
Release date
2022-01-05
Hebei Weibang Biotechnology Co., Ltd
Product
(E,E)-Farnesol 106-28-5
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
500000kg
Release date
2024-11-05

106-28-5, (E,E)-Farnesol Related Search:


  • (E,E)-3,7,11-TRIMETHYL-2,6,10-DODECATRIEN-1-OL
  • (E,E)-FARNESOL
  • FEMA 2478
  • (2E,6E)-3,7,11-TRIMETHYL-DODECA-2,6,10-TRIEN-1-OL
  • (E)-farnesol,(E,E)-3,7,11-trimethyl-2,6-10-dodecatrien-1-ol
  • 3,7,11-TRIMETHYLDODECA-2,6,10-TRIEN-1-OL
  • ALL TRANS FARNESOL
  • TRANS,TRANS-FARNESOL
  • TRANS,TRANS-3,7,11-TRIMETHYL-2,6,10-DODECATRIEN-1-OL
  • (2E,6E)-Farnesol
  • (E)-farnesol
  • 2,6-Di-trans-Farnesol
  • 2-trans,6-trans-Farnesol
  • Farnesol, (E,E)-
  • Inhibitor A2
  • trans,trans-alpha-Farnesol
  • trans-Farnesol
  • (E,E)-3,7,11-Trimethyl-2,6,10-dodecatrien-1-ol, trans,trans-3,7,11-Trimethyl-2,6,10-dodecatrien-1-ol
  • trans,trans-Farnesol,(E,E)-3,7,11-Trimethyl-2,6,10-dodecatrien-1-ol, trans,trans-3,7,11-Trimethyl-2,6,10-dodecatrien-1-ol
  • (E,E)-3,7,11-TriMethyl-2,6,10-dodecatnen-1-ol
  • 3,7,11-TriMethyldodeca-2-trans,6-trans,10-trien-1-ol
  • all-E-Farnesol
  • trans,trans-Farnesol 96%
  • (2E,6E)-3,7,11-Trimethyl-2,6,10-dodecatrien-1-ol
  • (e,e)-FARNESOL 97+% FCC
  • 2,6,10-Dodecatrien-1-ol, 3,7,11-trimethyl-, (2E,6E)-
  • Farnesen Farnesol
  • Farnesol techn. (2E,6E)- isomer (major) in methanol
  • 106-28-5
  • Organic Building Blocks
  • Terpenes (Others)
  • Terpenes
  • Building Blocks
  • Acyclic
  • Alkenes
  • Aliphatics
  • Fatty Acid Derivatives & Lipids
  • 106-28-5