ChemicalBook > CAS DataBase List > BOC-ALA-ALA-OH

BOC-ALA-ALA-OH

Product Name
BOC-ALA-ALA-OH
CAS No.
27317-69-7
Chemical Name
BOC-ALA-ALA-OH
Synonyms
Boc-Ala-Ala;Boc-AA-OH;(tert-Butoxycarbonyl)-L-alanyl-L-alanine;BOC-ALA-ALA-OH;Boc-L-Ala-L-Ala-OH;BOC-ALA-ALA-OH H2O;BOC-L-ALANYL-L-ALANINE H2O;BOC-L-ALANYL-L-ALANINE MONOHYDRATE;N-tert-Butoxycarbonyl-L-alanyl-L-alanine;L-Alanine,N-[(1,1-dimethylethoxy)carbonyl]-L-alanyl-
CBNumber
CB4673170
Molecular Formula
C11H20N2O5
Formula Weight
260.29
MOL File
27317-69-7.mol
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BOC-ALA-ALA-OH Property

Melting point:
132-133 °C
Boiling point:
483.5±30.0 °C(Predicted)
Density 
1.163±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,2-8°C
solubility 
DMSO (Slightly), Methanol (Slightly)
pka
3.52±0.10(Predicted)
form 
Solid
color 
White to Off-White
Stability:
Hygroscopic
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TCI Chemical
Product number
B6187
Product name
(tert-Butoxycarbonyl)-L-alanyl-L-alanine
Packaging
1G
Price
$48
Updated
2025/07/31
TCI Chemical
Product number
B6187
Product name
(tert-Butoxycarbonyl)-L-alanyl-L-alanine
Packaging
5G
Price
$143
Updated
2025/07/31
Usbiological
Product number
236070
Product name
Boc-Ala-Ala-OH
Packaging
1g
Price
$186
Updated
2021/12/16
Usbiological
Product number
264954
Product name
Boc-Ala-Ala-OH
Packaging
2g
Price
$375
Updated
2021/12/16
Activate Scientific
Product number
AS112881
Product name
Boc-Ala-Ala-OH
Purity
97%
Packaging
1g
Price
$43
Updated
2021/12/16
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BOC-ALA-ALA-OH Chemical Properties,Usage,Production

Uses

N-Phthalyl-alanine is used in the preparation of endothiopeptide inhibitors of HIV-1 Protease.

Synthesis

1948-31-8

24424-99-5

27317-69-7

GENERAL STEPS: L-alanyl-L-alanine (1 mmol) was slowly added to a solution of ethanol (1 mL) containing guanidine hydrochloride (15 mmol) and di-tert-butyl dicarbonate (2.5-3 mmol) under stirring conditions, maintaining the reaction temperature at 35-40°C. The reaction mixture was stirred continuously until a clarified solution was formed. Subsequently, the ethanol was removed by evaporation under reduced pressure. The residue was washed sequentially with distilled water (2 mL) and hexane or petroleum ether (2 mL) to obtain nearly pure N-tert-butoxycarbonyl-alanylalanine. If further product purity is required, the crude product can be purified by recrystallization.

References

[1] Journal of Organic Chemistry, 2007, vol. 72, # 2, p. 525 - 531
[2] Journal of the American Chemical Society, 2000, vol. 122, # 12, p. 2687 - 2697
[3] Journal of Organic Chemistry, 1994, vol. 59, # 19, p. 5784 - 5793
[4] Tetrahedron Letters, 2011, vol. 52, # 12, p. 1260 - 1264
[5] Journal of Medicinal Chemistry, 2005, vol. 48, # 16, p. 5305 - 5320

BOC-ALA-ALA-OH Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from BOC-ALA-ALA-OH manufacturers

Sichuan HongRi Pharma-Tech Co.,Ltd
Product
Boc-Ala-Ala-OH 27317-69-7
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1T+
Release date
2024-04-10
Henan Aochuang Chemical Co.,Ltd.
Product
BOC-ALA-ALA-OH 27317-69-7
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1Ton
Release date
2022-10-12

27317-69-7, BOC-ALA-ALA-OHRelated Search:


  • BOC-ALA-ALA-OH
  • BOC-ALA-ALA-OH H2O
  • BOC-L-ALANYL-L-ALANINE H2O
  • BOC-L-ALANYL-L-ALANINE MONOHYDRATE
  • N-tert-Butoxycarbonyl-L-alanyl-L-alanine
  • Boc-Ala-Ala
  • Boc-AA-OH
  • Boc-L-Ala-L-Ala-OH
  • L-Alanine,N-[(1,1-dimethylethoxy)carbonyl]-L-alanyl-
  • (2S)-2-[(2S)-2-{[(tert-butoxy)carbonyl]amino}propanamido]propanoic acid
  • (tert-Butoxycarbonyl)-L-alanyl-L-alanine
  • 27317-69-7