BOC-ALA-ALA-OH
- Product Name
- BOC-ALA-ALA-OH
- CAS No.
- 27317-69-7
- Chemical Name
- BOC-ALA-ALA-OH
- Synonyms
- Boc-Ala-Ala;Boc-AA-OH;(tert-Butoxycarbonyl)-L-alanyl-L-alanine;BOC-ALA-ALA-OH;Boc-L-Ala-L-Ala-OH;BOC-ALA-ALA-OH H2O;BOC-L-ALANYL-L-ALANINE H2O;BOC-L-ALANYL-L-ALANINE MONOHYDRATE;N-tert-Butoxycarbonyl-L-alanyl-L-alanine;L-Alanine,N-[(1,1-dimethylethoxy)carbonyl]-L-alanyl-
- CBNumber
- CB4673170
- Molecular Formula
- C11H20N2O5
- Formula Weight
- 260.29
- MOL File
- 27317-69-7.mol
BOC-ALA-ALA-OH Property
- Melting point:
- 132-133 °C
- Boiling point:
- 483.5±30.0 °C(Predicted)
- Density
- 1.163±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,2-8°C
- solubility
- DMSO (Slightly), Methanol (Slightly)
- pka
- 3.52±0.10(Predicted)
- form
- Solid
- color
- White to Off-White
- Stability:
- Hygroscopic
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- B6187
- Product name
- (tert-Butoxycarbonyl)-L-alanyl-L-alanine
- Packaging
- 1G
- Price
- $48
- Updated
- 2025/07/31
- Product number
- B6187
- Product name
- (tert-Butoxycarbonyl)-L-alanyl-L-alanine
- Packaging
- 5G
- Price
- $143
- Updated
- 2025/07/31
- Product number
- 236070
- Product name
- Boc-Ala-Ala-OH
- Packaging
- 1g
- Price
- $186
- Updated
- 2021/12/16
- Product number
- 264954
- Product name
- Boc-Ala-Ala-OH
- Packaging
- 2g
- Price
- $375
- Updated
- 2021/12/16
- Product number
- FB48198
- Product name
- Boc-Ala-Ala-OH
- Packaging
- 5G
- Price
- $220
- Updated
- 2021/12/16
BOC-ALA-ALA-OH Chemical Properties,Usage,Production
Uses
N-Phthalyl-alanine is used in the preparation of endothiopeptide inhibitors of HIV-1 Protease.
Synthesis
1948-31-8
24424-99-5
27317-69-7
GENERAL STEPS: L-alanyl-L-alanine (1 mmol) was slowly added to a solution of ethanol (1 mL) containing guanidine hydrochloride (15 mmol) and di-tert-butyl dicarbonate (2.5-3 mmol) under stirring conditions, maintaining the reaction temperature at 35-40°C. The reaction mixture was stirred continuously until a clarified solution was formed. Subsequently, the ethanol was removed by evaporation under reduced pressure. The residue was washed sequentially with distilled water (2 mL) and hexane or petroleum ether (2 mL) to obtain nearly pure N-tert-butoxycarbonyl-alanylalanine. If further product purity is required, the crude product can be purified by recrystallization.
References
[1] Journal of Organic Chemistry, 2007, vol. 72, # 2, p. 525 - 531
[2] Journal of the American Chemical Society, 2000, vol. 122, # 12, p. 2687 - 2697
[3] Journal of Organic Chemistry, 1994, vol. 59, # 19, p. 5784 - 5793
[4] Tetrahedron Letters, 2011, vol. 52, # 12, p. 1260 - 1264
[5] Journal of Medicinal Chemistry, 2005, vol. 48, # 16, p. 5305 - 5320
BOC-ALA-ALA-OH Preparation Products And Raw materials
Raw materials
Preparation Products
BOC-ALA-ALA-OH Suppliers
- Tel
- --
- Fax
- --
- swiss@sennchem.com
- Country
- Switzerland
- ProdList
- 3143
- Advantage
- 71
View Lastest Price from BOC-ALA-ALA-OH manufacturers
- Product
- Boc-Ala-Ala-OH 27317-69-7
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1T+
- Release date
- 2024-04-10
- Product
- BOC-ALA-ALA-OH 27317-69-7
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1Ton
- Release date
- 2022-10-12