BOC-VAL-PRO-OH

Product Name: BOC-VAL-PRO-OH
CAS No.: 23361-28-6
Chemical Name: BOC-VAL-PRO-OH
Synonyms: Boc-Val-Pro;Boc-Val-L-Pro;BOC-VAL-PRO-OH;-3-methylbutanoyl);Boc-L-Val-L-Pro-OH;BOC-L-VALYL PROLINE;N-BOC-L-VALYL-L-PROLINE;(Tert-Butoxy)Carbonyl Val-Pro-OH;N-tert-Butoxycarbonyl-L-valyl-L-proline;N-(tert-butyloxycarbonyl)-L-valyl-L-proline
CBNumber: CB7177422
Molecular Formula: C15H26N2O5
Formula Weight: 314.38
MOL File: 23361-28-6.mol

More

Less

BOC-VAL-PRO-OH Property

Melting point:: 137-138 °C
Boiling point:: 503.2±45.0 °C(Predicted)
Density: 1.171±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,2-8°C
pka: 3.50±0.20(Predicted)
form: Solid

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

TRC

Product number: B663298
Product name: BOC-VAL-PRO-OH
Packaging: 10mg
Price: $45
Updated: 2021/12/16

Usbiological

Product number: 236722
Product name: Boc-Val-Pro-OH
Packaging: 250mg
Price: $184
Updated: 2021/12/16

Usbiological

Product number: 264996
Product name: Boc-Val-Pro-OH
Packaging: 500mg
Price: $333
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB48372
Product name: Boc-Val-Pro-OH
Packaging: 500mg
Price: $60
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB48372
Product name: Boc-Val-Pro-OH
Packaging: 1g
Price: $111.4
Updated: 2021/12/16

More

Less

BOC-VAL-PRO-OH Chemical Properties,Usage,Production

Uses

Boc-Val-Pro-OH is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

Synthesis

38017-75-3

23361-28-6

N-[(1,1-dimethylethoxy)carbonyl]-L-valyl-L-proline (Compound 2) was prepared from compound (CAS: 38017-75-3) by alkali hydrolysis reaction using a modified literature method. The procedure was as follows: compound 1 (1.372 g, 4.18 mmol) was dissolved in a solvent mixture of tetrahydrofuran (THF) and water (3:1 volume ratio, total volume of 80 mL, wherein 60 mL of THF and 20 mL of water). Subsequently, lithium hydroxide monohydrate (LiOH-H2O, 0.878 g, 20.89 mmol) was added and the reaction mixture was stirred at room temperature for 2 hours. Upon completion of the reaction, the reaction was acidified with 0.5 M hydrochloric acid (50 mL) to quench the reaction, followed by extraction with ethyl acetate (EtOAc, 4 × 60 mL). The organic phases were combined, washed with saturated saline (1 × 100 mL) and dried over anhydrous magnesium sulfate (MgSO4). The solvent was removed by evaporation under reduced pressure to give a white solid product (1.186 g, 90% yield). The structure of the product was confirmed by 1H NMR, 13C NMR and ESI-MS: 1H NMR (400 MHz, CDCl3) δ 9.37 (br s, 1H, COOH), 5.46 (d, J = 9.4 Hz, 1H, NH), 4.55 (dd, J = 8.1, 4.8 Hz, 1H, Pro-αH), 4.26 (dd, J = 9.4, 6.4, 6.4, 6.4), 1H, Pro-αH), 1H, Pro-αH, 1H, Pro-αH), 1H, Pro-αH, Pro-αH, Pro-αH, Pro-αH. J = 9.4, 6.8 Hz, 1H, Val-αH), 3.83-3.59 (m, 2H, Pro-δH), 2.25-1.86 (m, 5H, Pro-βH, Pro-γH, Val-βH), 1.40 (s, 9H, tBu), 0.98 (d, J = 6.7 Hz, 3H, Val-γH), 0.91 (d , J = 6.7 Hz, 3H, Val-γH); 13C NMR (101 MHz, CDCl3) δ 174.5, 172.4, 155.9, 79.6, 59.1, 57.0, 47.5, 31.2, 28.5, 28.3, 24.8, 19.2, 17.6; ESI-MS (m/z): [M+Na]+ calculated for C15H26N2NaO5 337.1739, found 337.1734.

References

[1] Tetrahedron, 2018, vol. 74, # 12, p. 1184 - 1190
[2] Journal of Organic Chemistry, 2003, vol. 68, # 12, p. 5006 - 5008
[3] Recueil: Journal of the Royal Netherlands Chemical Society, 1980, vol. 99, # 4, p. 124 - 130
[4] Polish Journal of Chemistry, 1988, vol. 62, # 4-6, p. 457 - 464
[5] Bollettino Chimico Farmaceutico, 1999, vol. 138, # 4, p. 160 - 164

BOC-VAL-PRO-OH Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

BOC-VAL-PRO-OH Suppliers

China 82 India 1 Switzerland 1 United Kingdom 3 United States 10 Global 97

Capot Chemical Co., Ltd

Tel: +86 (0) 571 85 58 67 18
Fax: 0086-571-85864795
Country: China
ProdList: 18207
Advantage: 66

Jia Xing Isenchem Co.,Ltd

Tel: 0573-85285100 18627885956
Fax: 0573-85285100
Email: isenchem@163.com
Country: China
ProdList: 9310
Advantage: 66

Chemsky (shanghai) International Co.,Ltd

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 15402
Advantage: 60

Shandong Xiya Chemical Co., Ltd

Tel: 4009903999 13355009207
Fax: 0539-6365991
Email: 3007715519@qq.com
Country: China
ProdList: 18729
Advantage: 57

Shanghai Sunway Pharmaceutical Technology Co., Ltd

Tel: 18270980682
Fax: 021 51613951
Email: mlcheng@sunwaypharm.cn
Country: China
ProdList: 8669
Advantage: 57

Shanghai Sphchem Co., Ltd.

Tel: 021-56491756 13512199871
Fax: 021-5649-1756
Email: 2819742715@qq.com
Country: China
ProdList: 4000
Advantage: 55

Hangzhou Sage Chemical Co., Ltd.

Tel: +86057186818502 13588463833
Fax: Pls mail us for more information!
Email: info@sagechem.com
Country: China
ProdList: 10266
Advantage: 58

9ding chemical ( Shanghai) Limited

Tel: 4009209199
Fax: 86-021-52271987
Email: sales@9dingchem.com
Country: China
ProdList: 18209
Advantage: 56

Wuxi Zhongkun Biochemical Technology Co., Ltd.

Tel: 0510-85629785 18013409632
Fax: 051085625359
Email: sales@reading-chemicals.com
Country: China
ProdList: 15178
Advantage: 58

Finetech Industry Limited

Tel: 027-87465837 19945049750
Fax: 027-8777-2287
Email: sales@finetechnology-ind.com
Country: China
ProdList: 9637
Advantage: 58

More

Less

View Lastest Price from BOC-VAL-PRO-OH manufacturers

Sichuan HongRi Pharma-Tech Co.,Ltd

Product: Boc-Val-Pro-OH 23361-28-6
Price: US $0.00-0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1T+
Release date: 2024-04-10

Hebei Dangtong Import and export Co LTD

Product: BOC-VAL-PRO-OH 23361-28-6
Price: US $1590.00-1400.00/kilograms
Min. Order: 1kilograms
Purity: 99%
Supply Ability: 100tons
Release date: 2023-02-22

Career Henan Chemical Co

Product: BOC-VAL-PRO-OH 23361-28-6
Price: US $6.60/KG
Min. Order: 1KG
Purity: 97%-99%
Supply Ability: 1kg-1000kg
Release date: 2019-12-26

23361-28-6, BOC-VAL-PRO-OHRelated Search:

BOC-VAL-GLY-OH BOC-GLY-PRO-OH BOC-ALA-ALA-OH N-(tert-Butoxycarbonyl)glycylglycine BOC-ILE-PRO-OME CARBAMIC ACID, [2-(DIMETHYLAMINO)ETHYL]-, 1,1-DIMETHYLETHYL ESTER BOC-VAL-PRO-OH (S)-2-N-BOC-AMINO-1-PYRROLIDIN-1-YL-PROPAN-1-ONE BOC-ALA-GLY-OH DIETHYLCARBAMOYLMETHYL-CARBAMIC ACID TERT-BUTYL ESTER TERT-BUTYL 2-(BUTYLAMINO)ETHYLCARBAMATE (S)-1-N-BOC-2-METHYL-1-PYRROLIDIN-1-YLMETHYL-PROPYLAMINE tert-butyl N-[2-(dimethylamino)-2-oxoethyl]carbamate H-VAL-PRO-OH HCL BOC-ALA-PRO-OH BOC-VAL-NH2

BOC-L-VALYL PROLINE

BOC-VAL-PRO-OH

Boc-L-Val-L-Pro-OH

-3-methylbutanoyl)

(S)-1-((S)-2-((tert-Butoxycarbonyl)amino)-3-methylbutanoyl)pyrrolidine-2-carboxylic acid

(Tert-Butoxy)Carbonyl Val-Pro-OH

N-tert-Butoxycarbonyl-L-valyl-L-proline

Boc-Val-Pro

L-Proline, N-[(1,1-diMethylethoxy)carbonyl]-L-valyl-

N-BOC-L-VALYL-L-PROLINE

(2S)-1-[(2S)-2-{[(tert-butoxy)carbonyl]amino}-3-methylbutanoyl]pyrrolidine-2-carboxylic acid

N-(tert-butyloxycarbonyl)-L-valyl-L-proline

N-[(1,1-Dimethylethoxy)carbonyl]-L-valyl-L-proline

(2S)-1-[(2S)-3-methyl-2-[(2-methylpropan-2-yl)oxycarbonylamino]butanoyl]pyrrolidine-2-carboxylic acid

Boc-Val-L-Pro

23361-28-6

C15H26N2O5