BOC-VAL-PRO-OH
- Product Name
- BOC-VAL-PRO-OH
- CAS No.
- 23361-28-6
- Chemical Name
- BOC-VAL-PRO-OH
- Synonyms
- Boc-Val-Pro;Boc-Val-L-Pro;BOC-VAL-PRO-OH;-3-methylbutanoyl);Boc-L-Val-L-Pro-OH;BOC-L-VALYL PROLINE;N-BOC-L-VALYL-L-PROLINE;(Tert-Butoxy)Carbonyl Val-Pro-OH;N-tert-Butoxycarbonyl-L-valyl-L-proline;N-(tert-butyloxycarbonyl)-L-valyl-L-proline
- CBNumber
- CB7177422
- Molecular Formula
- C15H26N2O5
- Formula Weight
- 314.38
- MOL File
- 23361-28-6.mol
BOC-VAL-PRO-OH Property
- Melting point:
- 137-138 °C
- Boiling point:
- 503.2±45.0 °C(Predicted)
- Density
- 1.171±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,2-8°C
- pka
- 3.50±0.20(Predicted)
- form
- Solid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- B663298
- Product name
- BOC-VAL-PRO-OH
- Packaging
- 10mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- 236722
- Product name
- Boc-Val-Pro-OH
- Packaging
- 250mg
- Price
- $184
- Updated
- 2021/12/16
- Product number
- 264996
- Product name
- Boc-Val-Pro-OH
- Packaging
- 500mg
- Price
- $333
- Updated
- 2021/12/16
- Product number
- FB48372
- Product name
- Boc-Val-Pro-OH
- Packaging
- 1g
- Price
- $111.4
- Updated
- 2021/12/16
- Product number
- AAA0002202
- Product name
- BOC-VAL-PRO-OH
- Purity
- 95.00%
- Packaging
- 250MG
- Price
- $141.75
- Updated
- 2021/12/16
BOC-VAL-PRO-OH Chemical Properties,Usage,Production
Uses
Boc-Val-Pro-OH is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
Synthesis
38017-75-3
23361-28-6
N-[(1,1-dimethylethoxy)carbonyl]-L-valyl-L-proline (Compound 2) was prepared from compound (CAS: 38017-75-3) by alkali hydrolysis reaction using a modified literature method. The procedure was as follows: compound 1 (1.372 g, 4.18 mmol) was dissolved in a solvent mixture of tetrahydrofuran (THF) and water (3:1 volume ratio, total volume of 80 mL, wherein 60 mL of THF and 20 mL of water). Subsequently, lithium hydroxide monohydrate (LiOH-H2O, 0.878 g, 20.89 mmol) was added and the reaction mixture was stirred at room temperature for 2 hours. Upon completion of the reaction, the reaction was acidified with 0.5 M hydrochloric acid (50 mL) to quench the reaction, followed by extraction with ethyl acetate (EtOAc, 4 × 60 mL). The organic phases were combined, washed with saturated saline (1 × 100 mL) and dried over anhydrous magnesium sulfate (MgSO4). The solvent was removed by evaporation under reduced pressure to give a white solid product (1.186 g, 90% yield). The structure of the product was confirmed by 1H NMR, 13C NMR and ESI-MS: 1H NMR (400 MHz, CDCl3) δ 9.37 (br s, 1H, COOH), 5.46 (d, J = 9.4 Hz, 1H, NH), 4.55 (dd, J = 8.1, 4.8 Hz, 1H, Pro-αH), 4.26 (dd, J = 9.4, 6.4, 6.4, 6.4), 1H, Pro-αH), 1H, Pro-αH, 1H, Pro-αH), 1H, Pro-αH, Pro-αH, Pro-αH, Pro-αH. J = 9.4, 6.8 Hz, 1H, Val-αH), 3.83-3.59 (m, 2H, Pro-δH), 2.25-1.86 (m, 5H, Pro-βH, Pro-γH, Val-βH), 1.40 (s, 9H, tBu), 0.98 (d, J = 6.7 Hz, 3H, Val-γH), 0.91 (d , J = 6.7 Hz, 3H, Val-γH); 13C NMR (101 MHz, CDCl3) δ 174.5, 172.4, 155.9, 79.6, 59.1, 57.0, 47.5, 31.2, 28.5, 28.3, 24.8, 19.2, 17.6; ESI-MS (m/z): [M+Na]+ calculated for C15H26N2NaO5 337.1739, found 337.1734.
References
[1] Tetrahedron, 2018, vol. 74, # 12, p. 1184 - 1190
[2] Journal of Organic Chemistry, 2003, vol. 68, # 12, p. 5006 - 5008
[3] Recueil: Journal of the Royal Netherlands Chemical Society, 1980, vol. 99, # 4, p. 124 - 130
[4] Polish Journal of Chemistry, 1988, vol. 62, # 4-6, p. 457 - 464
[5] Bollettino Chimico Farmaceutico, 1999, vol. 138, # 4, p. 160 - 164
BOC-VAL-PRO-OH Preparation Products And Raw materials
Raw materials
Preparation Products
BOC-VAL-PRO-OH Suppliers
- Tel
- --
- Fax
- --
- swiss@sennchem.com
- Country
- Switzerland
- ProdList
- 3143
- Advantage
- 71
View Lastest Price from BOC-VAL-PRO-OH manufacturers
- Product
- Boc-Val-Pro-OH 23361-28-6
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 98%
- Supply Ability
- 1T+
- Release date
- 2024-04-10
- Product
- BOC-VAL-PRO-OH 23361-28-6
- Price
- US $1590.00-1400.00/kilograms
- Min. Order
- 1kilograms
- Purity
- 99%
- Supply Ability
- 100tons
- Release date
- 2023-02-22
- Product
- BOC-VAL-PRO-OH 23361-28-6
- Price
- US $6.60/KG
- Min. Order
- 1KG
- Purity
- 97%-99%
- Supply Ability
- 1kg-1000kg
- Release date
- 2019-12-26