4-Amino-3-nitrobenzonitrile
- Product Name
- 4-Amino-3-nitrobenzonitrile
- CAS No.
- 6393-40-4
- Chemical Name
- 4-Amino-3-nitrobenzonitrile
- Synonyms
- BUTTPARK 96\04-65;4-Cyano-2-nitroaniline;2-Nitro-4-cyanoaniline;3-Nitro-4-Aminobenzonitrile;4-AMINO-3-NITROBENZONITRILE;Benzonitrile, 4-amino-3-nitro-;4-Amino-3-nitrobenzonitrile >4-Amino-3-nitrobenzonitrile,98%;4-AMINO-3-NITROBENZONITRILE 98%;4-AMino-3-nitrobenzonitrile, 97+%
- CBNumber
- CB4675356
- Molecular Formula
- C7H5N3O2
- Formula Weight
- 163.13
- MOL File
- 6393-40-4.mol
4-Amino-3-nitrobenzonitrile Property
- Melting point:
- 159-162 °C (lit.)
- Boiling point:
- 349.8±32.0 °C(Predicted)
- Density
- 1.41±0.1 g/cm3(Predicted)
- storage temp.
- Keep in dark place,Inert atmosphere,Room temperature
- solubility
- Soluble in ethanol and benzene.
- pka
- -3.52±0.10(Predicted)
- form
- Powder, Crystals or Crystalline Powder
- color
- Yellow
- BRN
- 778939
- InChI
- InChI=1S/C7H5N3O2/c8-4-5-1-2-6(9)7(3-5)10(11)12/h1-3H,9H2
- InChIKey
- JAHADAZIDZMHOP-UHFFFAOYSA-N
- SMILES
- C(#N)C1=CC=C(N)C([N+]([O-])=O)=C1
- CAS DataBase Reference
- 6393-40-4(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi,Xn
- Risk Statements
- 36/37/38-20/21/22
- Safety Statements
- 26-36-36/37/39
- RIDADR
- 3276
- WGK Germany
- 3
- Hazard Note
- Irritant
- HazardClass
- 6.1
- PackingGroup
- III
- HS Code
- 29269090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 324698
- Product name
- 4-Amino-3-nitrobenzonitrile
- Purity
- 98%
- Packaging
- 5g
- Price
- $61.6
- Updated
- 2023/06/20
- Product number
- A2447
- Product name
- 4-Amino-3-nitrobenzonitrile
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $170
- Updated
- 2025/07/31
- Product number
- A2447
- Product name
- 4-Amino-3-nitrobenzonitrile
- Purity
- >98.0%(GC)
- Packaging
- 25g
- Price
- $678
- Updated
- 2025/07/31
- Product number
- A618398
- Product name
- 4-Amino-3-nitrobenzonitrile
- Packaging
- 1g
- Price
- $55
- Updated
- 2021/12/16
- Product number
- OR01561
- Product name
- 4-Amino-3-nitrobenzonitrile
- Packaging
- 1g
- Price
- $15
- Updated
- 2021/12/16
4-Amino-3-nitrobenzonitrile Chemical Properties,Usage,Production
Chemical Properties
white to light yellow crystal powder
Uses
4-Amino-3-nitrobenzonitrile is used in gamma irradiations effect on release of this compound from polyanhydride matrixes.
Uses
Gamma irradiations effect on release of 4-amino-3-nitrobenzonitrile from polyanhydride matrixes.
Synthesis Reference(s)
Journal of Medicinal Chemistry, 36, p. 1746, 1993 DOI: 10.1021/jm00064a008
Synthesis
35704-19-9
6393-40-4
General procedure for the synthesis of 4-amino-3-nitrobenzonitrile from 4'-cyanoacetanilide: potassium nitrate (15.6 mmol) was dissolved in 8 mL of concentrated sulfuric acid and the mixture was cooled to below 0 °C. Under this cooling condition, 7.8 mmol of 4'-cyanoacetanilide was slowly added, keeping the reaction temperature at 0 °C for 3.5 hours. Upon completion of the reaction, the mixture was poured into an ice water bath and the resulting yellow solid was collected by filtration and washed with a small amount of cold water. Subsequently, the resulting product was suspended in 30 mL of 2 mol/L sulfuric acid solution and heated under reflux conditions for 3 hours. At the end of the reaction, the suspension was cooled to room temperature, and the yellow solid was again collected by filtration and washed with a small amount of cold water to finally obtain the target product 4-amino-3-nitrobenzonitrile in 74% yield.
References
[1] Journal of the Brazilian Chemical Society, 2018, vol. 29, # 6, p. 1304 - 1317
[2] Journal of the Chemical Society, 1950, p. 1722,1725
[3] Journal of Medicinal Chemistry, 1995, vol. 38, # 10, p. 1786 - 1792
[4] Australian Journal of Chemistry, 1994, vol. 47, # 2, p. 247 - 262
[5] Journal of Medicinal Chemistry, 1993, vol. 36, # 12, p. 1746 - 1753
4-Amino-3-nitrobenzonitrile Preparation Products And Raw materials
Raw materials
Preparation Products
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View Lastest Price from 4-Amino-3-nitrobenzonitrile manufacturers
- Product
- 4-Amino-3-nitrobenzonitrile 6393-40-4
- Price
- US $100.00-1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2023-12-25
- Product
- 4-Amino-3-nitrobenzonitrile 6393-40-4
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-10
- Product
- 4-Amino-3-nitrobenzonitrile 6393-40-4
- Price
- US $15.00-10.00/KG
- Min. Order
- 1KG
- Purity
- 99%+ HPLC
- Supply Ability
- Monthly supply of 1 ton
- Release date
- 2021-07-09