Uses
ChemicalBook > CAS DataBase List > 4-(HEXAFLUORO-2-HYDROXYISOPROPYL)ANILINE

4-(HEXAFLUORO-2-HYDROXYISOPROPYL)ANILINE

Uses
Product Name
4-(HEXAFLUORO-2-HYDROXYISOPROPYL)ANILINE
CAS No.
722-92-9
Chemical Name
4-(HEXAFLUORO-2-HYDROXYISOPROPYL)ANILINE
Synonyms
4-(HexafL;JACS-722-92-9;2-(4-Amino-Phenyl;uoro-2-hydroxyisopropyL;2-(4-Aminophenyl) hexafluoropropan-ol;2-(4-AMINOPHENYL)HEXAFLUORO-2-PROPANOL;4-(HEXAFLUORO-2-HYDROXYISOPROPYL)ANILINE;4-(Hexafluoro-2-hydroxyisopropyl)aniline97%;4-(Hexafluoro-2-hydroxyisopropyl)aniline 97%;4-Amino---Bis(Trifluoromethyl)Benzyl Alcohol
CBNumber
CB4677860
Molecular Formula
C9H7F6NO
Formula Weight
259.15
MOL File
722-92-9.mol
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4-(HEXAFLUORO-2-HYDROXYISOPROPYL)ANILINE Property

Melting point:
147-152 °C
Boiling point:
292.9±40.0 °C(Predicted)
Density 
1.505±0.06 g/cm3(Predicted)
storage temp. 
Keep in dark place,Inert atmosphere,2-8°C
pka
9.86±0.15(Predicted)
form 
Crystalline Powder
color 
Light brown
BRN 
1473737
InChI
InChI=1S/C9H7F6NO/c10-8(11,12)7(17,9(13,14)15)5-1-3-6(16)4-2-5/h1-4,17H,16H2
InChIKey
TZEJXCIGVMTMDY-UHFFFAOYSA-N
SMILES
C(O)(C(F)(F)F)(C(F)(F)F)C1C=CC(N)=CC=1
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
37/39-26
RIDADR 
2811
Hazard Note 
Irritant/Keep Cold under Argon
HazardClass 
IRRITANT
HazardClass 
6.1
PackingGroup 
HS Code 
29221990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H301Toxic if swalloed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P405Store locked up.

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N-Bromosuccinimide Price

TRC
Product number
H290048
Product name
4-(Hexafluoro-2-hydroxyisopropyl)aniline
Packaging
50mg
Price
$45
Updated
2021/12/16
TRC
Product number
H290048
Product name
4-(Hexafluoro-2-hydroxyisopropyl)aniline
Packaging
100mg
Price
$60
Updated
2021/12/16
SynQuest Laboratories
Product number
4656-3-21
Product name
4-(Hexafluoro-2-hydroxyisopropyl)aniline
Purity
97%
Packaging
5G
Price
$65
Updated
2021/12/16
SynQuest Laboratories
Product number
4656-3-21
Product name
4-(Hexafluoro-2-hydroxyisopropyl)aniline
Purity
97%
Packaging
1g
Price
$35
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA92890
Product name
4-Amino-A,alpha-Bis(Trifluoromethyl)-Benzenemethanol
Packaging
1g
Price
$105
Updated
2021/12/16
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4-(HEXAFLUORO-2-HYDROXYISOPROPYL)ANILINE Chemical Properties,Usage,Production

Uses

2-(4-aminobenzene)-1,1,1,3,3,3-hexafluoro-2-propanol can be used to prepare bisphenol AF. Bisphenol AF (hexafluorobisphenol A: 2,2-bis-(4-hydroxyphenyl)hexafluoropropane) is mainly used as a vulcanization accelerator for fluororubber.

Chemical Properties

Light brown crystalline powder

Synthesis

62-53-3

684-16-2

722-92-9

To a xylene solution of aniline (7, 21.47 mmol) and p-toluenesulfonic acid (pTSA, 1.28 mmol) was added hexafluoroacetone trihydrate (8, 64.42 mmol) and the reaction mixture was heated to reflux for 5 hours. Upon completion of the reaction, it was cooled to room temperature to allow the product 4-(hexafluoro-2-hydroxyisopropyl)aniline (9) to crystallize and precipitate, which was collected by filtration and used directly in the next step of the reaction.

References

[1] Bioorganic and Medicinal Chemistry Letters, 2006, vol. 16, # 6, p. 1638 - 1642
[2] European Journal of Medicinal Chemistry, 2016, vol. 122, p. 744 - 755
[3] Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1990, vol. 39, # 2.2, p. 323 - 328
[4] Izvestiya Akademii Nauk SSSR, Seriya Khimicheskaya, 1990, # 2, p. 383 - 389
[5] Bulletin of the Academy of Sciences of the USSR, Division of Chemical Science (English Translation), 1990, vol. 39, # 2.2, p. 323 - 328

4-(HEXAFLUORO-2-HYDROXYISOPROPYL)ANILINE Preparation Products And Raw materials

Raw materials

Preparation Products

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4-(HEXAFLUORO-2-HYDROXYISOPROPYL)ANILINE Suppliers

Acros Organics
Tel
--
Fax
--
Email
info@acros.com
Country
Belgium
ProdList
6772
Advantage
81
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View Lastest Price from 4-(HEXAFLUORO-2-HYDROXYISOPROPYL)ANILINE manufacturers

Henan Aochuang Chemical Co.,Ltd.
Product
4-(Hexafluoro-2-hydroxyisopropyl)aniline 722-92-9
Price
US $0.00-0.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
1Ton
Release date
2022-10-09
Henan Fengda Chemical Co., Ltd
Product
4-(HEXAFLUORO-2-HYDROXYISOPROPYL)ANILINE 722-92-9
Price
US $50.00-1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2023-12-22
Honest Joy Holdings Limited
Product
4-(Hexafluoro-2-hydroxyisopropyl)aniline 722-92-9
Price
US $0.00/KG
Min. Order
1KG
Purity
98.0%
Supply Ability
100 tons
Release date
2022-02-20

722-92-9, 4-(HEXAFLUORO-2-HYDROXYISOPROPYL)ANILINERelated Search:


  • 4-(HEXAFLUORO-2-HYDROXYISOPROPYL)ANILINE
  • 4-AMINO-ALPHA,ALPHA-BIS(TRIFLUOROMETHYL)BENZYL ALCOHOL
  • 2-(4-AMINOPHENYL)HEXAFLUORO-2-PROPANOL
  • 4-amino-à-à-bis(trifluoromethyl)benzyl alcohol
  • 4-(Hexafluoro-2-hydroxyisopropyl)aniline 97%
  • 4-(Hexafluoro-2-hydroxyisopropyl)aniline97%
  • 2-(4-AMINO-PHENYL)-1,1,1,3,3,3-HEXAFLUORO-PROPAN-2-OL
  • 2-(4-Aminophenyl) hexafluoropropan-ol
  • 2-(4-Aminophenyl)-1,1,1,3,3,3-hexafluoro-2-propanol,97%
  • 2-(4-AMINOPHENYL)-1,1,1,3,3,3-HEXAFLUORO-2-PROPANOL
  • 2-(4-Amino-Phenyl
  • 4-Amino---Bis(Trifluoromethyl)Benzyl Alcohol
  • benzenemethanol, 4-amino-alpha,alpha-bis(trifluoromethyl)-
  • 2-(4-Aminophenyl)-1,1,1,3,3,3-hexafluoropropan-2-ol 97%
  • 4-(1,1,1,3,3,3-Hexafluoro-2-hydroxyprop-2-yl)aniline
  • 2-(4-AMinophenyl)-1,1,1,3,3,3-hexafluoro-2-propanol, 97% 5GR
  • 4-(1,1,1,3,3,3-Hexafluoro-2-hydroxyprop-2-yl)aniline, 4-[Perfluoro(2-hydroxyprop-2-yl)]aniline
  • 2-(4-Aminophenyl)-1,1,1,3,3,3-hexafluoropropan-2-ol97%
  • 4-Amino-A,alpha-Bis(Trifluoromethyl)-Benzenemethanol
  • JACS-722-92-9
  • 4-(HexafL
  • uoro-2-hydroxyisopropyL
  • Benzenemethanol, 4-amino-α,α-bis(trifluoromethyl)-
  • 4-(Hexafluoro-2-hydroxyisopropyl)anilineQ: What is 4-(Hexafluoro-2-hydroxyisopropyl)aniline Q: What is the CAS Number of 4-(Hexafluoro-2-hydroxyisopropyl)aniline Q: What is the storage condition of 4-(Hexafluoro-2-hydroxyisopropyl)aniline
  • 2-(4-Aminophenyl)-1,1,1,333-hexafluoropropane-2-ol
  • 722-92-9
  • C8H7F6NO
  • C9H7F6NO