3-BENZYL-3-AZABICYCLO[3.2.1]OCTAN-8-ONE

Product Name: 3-BENZYL-3-AZABICYCLO[3.2.1]OCTAN-8-ONE
CAS No.: 83507-33-9
Chemical Name: 3-BENZYL-3-AZABICYCLO[3.2.1]OCTAN-8-ONE
Synonyms: (1R,5S)-3-benzyl-3-azabicyclo[3.2.1]octan-8-one;3-Benzyl-3-azabicyclo[3.2...;4-(Boc-ami)-3,6-dichloropyridazine;3-Benzyl-3-azabicylo[3.2.1]octan-8-one;3-BENZYL-3-AZABICYCLO[3.2.1]OCTAN-8-ONE;3-(phenylmethyl)-3-Azabicyclo[3.2.1]octan-8-one;3-Azabicyclo[3.2.1]octan-8-one, 3-(phenylMethyl)-
CBNumber: CB4681553
Molecular Formula: C14H17NO
Formula Weight: 215.29
MOL File: 83507-33-9.mol

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3-BENZYL-3-AZABICYCLO[3.2.1]OCTAN-8-ONE Property

Boiling point:: 342.9±22.0 °C(Predicted)
Density: 1.140±0.06 g/cm3(Predicted)
storage temp.: 2-8°C
pka: 7.08±0.20(Predicted)
Appearance: Off-white to yellow Solid
InChI: InChI=1S/C14H17NO/c16-14-12-6-7-13(14)10-15(9-12)8-11-4-2-1-3-5-11/h1-5,12-13H,6-10H2
InChIKey: DCDAOVIVXGHHHU-UHFFFAOYSA-N
SMILES: C12C(=O)C(CC1)CN(CC1=CC=CC=C1)C2

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

SynQuest Laboratories

Product number: 4H56-1-827
Product name: 3-Benzyl-3-azabicyclo[3.2.1]octan-8-one
Purity: 97.0%
Packaging: 250mg
Price: $190
Updated: 2021/12/16

SynQuest Laboratories

Product number: 4H56-1-827
Product name: 3-Benzyl-3-azabicyclo[3.2.1]octan-8-one
Purity: 97.0%
Packaging: 1g
Price: $490
Updated: 2021/12/16

Matrix Scientific

Product number: 122235
Product name: 3-Benzyl-3-azabicyclo[3.2.1]octan-8-one
Purity: 97.0%
Packaging: 1g
Price: $528
Updated: 2021/12/16

Ambeed

Product number: A190701
Product name: 3-Benzyl-3-azabicyclo[3.2.1]octan-8-one
Purity: 97%
Packaging: 100mg
Price: $16
Updated: 2021/12/16

Ambeed

Product number: A190701
Product name: 3-Benzyl-3-azabicyclo[3.2.1]octan-8-one
Purity: 97%
Packaging: 250mg
Price: $22
Updated: 2021/12/16

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3-BENZYL-3-AZABICYCLO[3.2.1]OCTAN-8-ONE Chemical Properties,Usage,Production

Synthesis

50-00-0

120-92-3

100-46-9

83507-33-9

General procedure for the synthesis of 3-benzyl-3-azabicyclo[3.2.1]octan-8-one (Intermediate I-32) from formaldehyde, cyclopentanone, and benzylamine: In a 2L round-bottomed flask equipped with a condenser tube and nitrogen introduction tube, benzylamine (127 g, 1.2 mol, 1.0 equiv.) and methanol (800 mL) were added, followed by the slow dropwise addition of glacial acetic acid (127 g, 1.2 mol, 1.0 equiv). Intermediate I-31 (100 g, 1.2 mol, 1.0 eq.) and paraformaldehyde (107 g, 3.6 mol, 3.0 eq.) were then added. The reaction mixture was stirred at 80 °C for 3 hours and then continued at room temperature for 18 hours. Upon completion of the reaction, the excess solvent was removed by evaporation and the residue was diluted with ethyl acetate and solid sodium bisulfite (104 g) was added. The crude reaction mixture was continued to be stirred for 1.5 hours and subsequently extracted with ethyl acetate. The organic layers were combined, dried with anhydrous Na2SO4, filtered to remove solids and the filtrate was concentrated by evaporation. The crude product was purified by silica gel column chromatography to afford intermediate I-32 (47.2 g, 18% yield) as a yellow oil.1H-NMR (400 MHz, CDCl3) δ: 7.35 (m, 4H), 7.26 (m, 1H), 3.59 (s, 2H), 2.93 (m, 2H), 2.39 (d, J=10.8 Hz, 2H). 2.50 (m, 2H), 1.93 (m, 2H), 1.81 (m, 2H).MS (ESI): m/z 216.1 (M+H+).

References

[1] Patent: US2011/65694, 2011, A1. Location in patent: Page/Page column 64
[2] Journal of Medicinal Chemistry, 1994, vol. 37, # 18, p. 2831 - 2840
[3] Patent: US2009/12116, 2009, A1. Location in patent: Page/Page column 18

3-BENZYL-3-AZABICYCLO[3.2.1]OCTAN-8-ONE Preparation Products And Raw materials

Raw materials

Preparation Products

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3-BENZYL-3-AZABICYCLO[3.2.1]OCTAN-8-ONE Suppliers

China 146 India 2 Ukraine 1 United Kingdom 2 United States 16 Global 167

RR Scientific LLC

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View Lastest Price from 3-BENZYL-3-AZABICYCLO[3.2.1]OCTAN-8-ONE manufacturers

ZHENGZHOU JIUYI TIME NEW MATERIALS CO,.LTD

Product: 3-Benzyl-3-azabicyclo[3.2.1]octan-8-one 83507-33-9
Price: US $2.00-6.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 100kg
Release date: 2025-08-05

Shaanxi Dideu New Materials Co. Ltd

Product: 3-BENZYL-3-AZABICYCLO[3.2.1]OCTAN-8-ONE 83507-33-9
Price: US $0.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 1000kg
Release date: 2025-06-28

Zhuozhou Wenxi import and Export Co., Ltd

Product: 3-BENZYL-3-AZABICYCLO[3.2.1]OCTAN-8-ONE 83507-33-9
Price: US $15.00-10.00/KG
Min. Order: 1KG
Purity: 99%+ HPLC
Supply Ability: Monthly supply of 1 ton
Release date: 2021-06-26

83507-33-9, 3-BENZYL-3-AZABICYCLO[3.2.1]OCTAN-8-ONERelated Search:

8-BENZYL-8-AZABICYCLO[3.2.1]OCTAN-3-ONE OXIME (1R,5R)-6β-Acetoxy-8-benzyl-8-azabicyclo[3.2.1]octan-3-one 8-BENZYL-8-AZABICYCLO[3.2.1]OCTAN-3-ONE 3-BENZYL-3-AZABICYCLO[3.2.1]OCTAN-8-ONE AKOS BC-0780

3-BENZYL-3-AZABICYCLO[3.2.1]OCTAN-8-ONE

3-Benzyl-3-azabicylo[3.2.1]octan-8-one

3-Azabicyclo[3.2.1]octan-8-one, 3-(phenylMethyl)-

3-Benzyl-3-azabicyclo[3.2...

(1R,5S)-3-benzyl-3-azabicyclo[3.2.1]octan-8-one

3-(phenylmethyl)-3-Azabicyclo[3.2.1]octan-8-one

4-(Boc-ami)-3,6-dichloropyridazine

83507-33-9

8350-33-9

835-07-3

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