4-Nitrobenzylamine hydrochloride
- Product Name
- 4-Nitrobenzylamine hydrochloride
- CAS No.
- 18600-42-5
- Chemical Name
- 4-Nitrobenzylamine hydrochloride
- Synonyms
- p-NitrobenzylamineHCl;4-NitrobenzylaMine HCl;p-nitro-benzylaminhydrochloride;P-NITROBENZYLAMINE HYDROCHLORIDE;4-NITROBENZYLAMINE HYDROCHLORIDE;4-NitrobenzylamineHydrochloride>4-nitrobenzylammonium hydrochloride;4-NITROBENZYLAMINE HYDROCHLORIDE 97%;(4-Nitrophenyl)methanamine hydrochloride;1-(4-Nitrophenyl)methanamine hydrochloride (1:1)
- CBNumber
- CB4689478
- Molecular Formula
- C7H9ClN2O2
- Formula Weight
- 188.61
- MOL File
- 18600-42-5.mol
4-Nitrobenzylamine hydrochloride Property
- Melting point:
- ~265 °C (dec.)(lit.)
- storage temp.
- under inert gas (nitrogen or Argon) at 2-8°C
- solubility
- methanol:glacial acetic acid (1:1): soluble25mg/mL, clear, colorless to light yellow
- form
- powder to crystal
- color
- White to Light yellow
- Water Solubility
- almost transparency
- BRN
- 3629994
- Stability:
- Stable. Incompatible with acids, acid chlorides, acid anhydrides, oxidizing agents.
- InChI
- InChI=1S/C7H8N2O2.ClH/c8-5-6-1-3-7(4-2-6)9(10)11;/h1-4H,5,8H2;1H
- InChIKey
- SMIXZZMSWYOQPW-UHFFFAOYSA-N
- SMILES
- C1([N+]([O-])=O)C=CC(CN)=CC=1.Cl
- CAS DataBase Reference
- 18600-42-5(CAS DataBase Reference)
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 191434
- Product name
- 4-Nitrobenzylamine hydrochloride
- Purity
- 97%
- Packaging
- 5g
- Price
- $143
- Updated
- 2025/07/31
- Product number
- 191434
- Product name
- 4-Nitrobenzylamine hydrochloride
- Purity
- 97%
- Packaging
- 25g
- Price
- $657
- Updated
- 2023/06/20
- Product number
- N0435
- Product name
- 4-Nitrobenzylamine Hydrochloride
- Purity
- >98.0%(HPLC)(T)
- Packaging
- 5g
- Price
- $405
- Updated
- 2025/07/31
- Product number
- N0435
- Product name
- 4-Nitrobenzylamine Hydrochloride
- Purity
- >98.0%(HPLC)(T)
- Packaging
- 25g
- Price
- $1372
- Updated
- 2025/07/31
- Product number
- N495838
- Product name
- 4-Nitrobenzylamine Hydrochloride
- Packaging
- 100mg
- Price
- $60
- Updated
- 2021/12/16
4-Nitrobenzylamine hydrochloride Chemical Properties,Usage,Production
Chemical Properties
light brown crystalline solid
Uses
4-Nitrobenzylamine hydrochloride was used in chemical modification of graphite powder and multiwalled carbon nanotubes. It was also used in the preparation of 2-fluoro-6-(4-nitrohenzylamino)purine.
Uses
4-Nitrobenzylamine hydrochloride was used in chemical modification of graphite powder and multiwalled carbon nanotubes. It was also used in the preparation of 2-fluoro-6-(4-nitrohenzylamino)purine.
Synthesis
619-72-7
18600-42-5
General procedure for the synthesis of 4-nitrobenzylamine hydrochloride from p-nitrobenzonitrile: To a 6.0 mL solution of toluene containing p-nitrobenzonitrile (1.0 g, 5.1 mmol, 1.0 eq.) under nitrogen protection was added TMDS (900 μL, 5.1 mmol, 1.0 eq.) or PMHS (610 μL, 10.2 mmol, 2.0 eq.) and Ti(Oi-Pr)4 (1.5 mL, 5.1 mmol, 1.0 eq.). The reaction mixture was heated at 60 °C for 24 h, during which the colorless solution gradually changed to black, and the reaction progress could be monitored by TLC or 1H NMR. Upon completion of the reaction, the mixture was cooled to room temperature and acidified with 1 M aqueous HCl (7.7 mL, 1.5 eq.) to obtain a clarified solution. Subsequently, the crude product was concentrated under reduced pressure, and the resulting solid was filtered and washed with pentane (3 x 50 mL). The washed solid was dissolved in ethanol and finally the filtrate was concentrated under reduced pressure to give the target product 4-nitrobenzylamine hydrochloride.
References
[1] Tetrahedron, 2014, vol. 70, # 4, p. 975 - 983
[2] Tetrahedron Letters, 2009, vol. 50, # 50, p. 7005 - 7007
[3] Recueil des Travaux Chimiques des Pays-Bas, 1992, vol. 111, # 1, p. 22 - 28
[4] Journal of Organic Chemistry, 2015, vol. 80, # 14, p. 7281 - 7287
4-Nitrobenzylamine hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
4-Nitrobenzylamine hydrochloride Suppliers
- Tel
- 13871097899
- Fax
- 13986215120
- chemistry888@126.com
- Country
- China
- ProdList
- 45
- Advantage
- 58
- Tel
- 1842-7358862 18427358864
- yihekeji@chembuying.com
- Country
- China
- ProdList
- 940
- Advantage
- 58
- Tel
- 18210857532; 18210857532
- Fax
- 86-10-82849933
- jkinfo@jkchemical.com
- Country
- China
- ProdList
- 96815
- Advantage
- 76
- Tel
- 400-6106006
- Fax
- 021-67582001/03/05
- saleschina@alfa-asia.com
- Country
- China
- ProdList
- 30123
- Advantage
- 84
- Tel
- 021-67121386
- Fax
- 021-67121385
- Sales-CN@TCIchemicals.com
- Country
- China
- ProdList
- 24529
- Advantage
- 81
- Tel
- 021-021-58432009 400-005-6266
- Fax
- 021-58436166
- sales8178@energy-chemical.com
- Country
- China
- ProdList
- 44801
- Advantage
- 61
- Tel
- +86 (0) 571 85 58 67 18
- Fax
- 0086-571-85864795
- Country
- China
- ProdList
- 18207
- Advantage
- 66
- Tel
- 021-54306202 13764082696
- info@hanhongsci.com
- Country
- China
- ProdList
- 42934
- Advantage
- 64
- Tel
- 4009903999 13355009207
- Fax
- 0539-6365991
- 3007715519@qq.com
- Country
- China
- ProdList
- 18729
- Advantage
- 57
- Tel
- +86 (21) 6435-5022
- Country
- China
- ProdList
- 4267
- Advantage
- 65
View Lastest Price from 4-Nitrobenzylamine hydrochloride manufacturers
- Product
- 4-Nitrobenzylamine hydrochloride 18600-42-5
- Price
- US $5.50/KG
- Min. Order
- 1KG
- Purity
- 98%min
- Supply Ability
- 1kg-100kg
- Release date
- 2020-01-08