4-BROMOPYRROLE-2-CARBOXYLIC ACID

Product Name: 4-BROMOPYRROLE-2-CARBOXYLIC ACID
CAS No.: 27746-02-7
Chemical Name: 4-BROMOPYRROLE-2-CARBOXYLIC ACID
Synonyms: 4-BROMO-1H-PYRROLE-2-CARBOXYLIC ACID;RARECHEM AL BE 1264;4-BROMOPYRROLE-2-CARBOXYLIC ACID;4-Bromo-1H-pyrrole-2-carboxylicaci;4-Bromo-1H-pyrrol-2-carboxylic acid;1H-Pyrrole-2-carboxylic acid, 4-bromo-;4-Bromo-1H-pyrrole-2-carboxylic acid, 95+%;4-bromo-1H-pyrrole-2-carboxylic acid(SALTDATA: FREE)
CBNumber: CB4703082
Molecular Formula: C5H4BrNO2
Formula Weight: 189.99
MOL File: 27746-02-7.mol

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4-BROMOPYRROLE-2-CARBOXYLIC ACID Property

Melting point:: 168-170°C
Boiling point:: 393.0±27.0 °C(Predicted)
Density: 1.969±0.06 g/cm3(Predicted)
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
form: powder
pka: 4.06±0.10(Predicted)
color: light beige

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Safety

Hazard Codes: Xi
HazardClass: IRRITANT
HS Code: 2933998090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

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N-Bromosuccinimide Price

TRC

Product number: B687168
Product name: 4-Bromo-1H-pyrrole-2-carboxylicacid
Packaging: 100mg
Price: $45
Updated: 2021/12/16

TRC

Product number: B687168
Product name: 4-Bromo-1H-pyrrole-2-carboxylicacid
Packaging: 500mg
Price: $65
Updated: 2021/12/16

Matrix Scientific

Product number: 047518
Product name: 4-Bromo-1H-pyrrole-2-carboxylic acid
Purity: >95%
Packaging: 5g
Price: $73
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB43789
Product name: 4-Bromopyrrole-2-carboxylic acid
Packaging: 1g
Price: $76.3
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FB43789
Product name: 4-Bromopyrrole-2-carboxylic acid
Packaging: 2g
Price: $122.1
Updated: 2021/12/16

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4-BROMOPYRROLE-2-CARBOXYLIC ACID Chemical Properties,Usage,Production

Synthesis

72652-32-5

27746-02-7

The general procedure for the synthesis of 4-bromopyrrole-2-carboxylic acid from 1-(4-bromo-1H-pyrrol-2-yl)-2,2,2-trichloroacetophenone is as follows: a THF solution (5 mL) of 1-(4-bromo-1H-pyrrol-2-yl)-2,2,2-trichloroacetophenone (4.7 mmol) was prepared as described by Belanger et al. ( Tetrahedron Lett. 1979, 2505-2508). The solution was stirred at room temperature and 1 mL of a 10% aqueous NaOH (aq) solution was added and stirring was continued for 1 hour. Upon completion of the reaction, the solvent was removed under reduced pressure and the crude product was partitioned between water and ethyl acetate. Subsequently, the pH was adjusted to 5 with 10% aqueous HCl. The phases were separated and the aqueous layer was extracted again with ethyl acetate. The organic phases were combined and dried with magnesium sulfate. Evaporation of the solvent gave 4-bromo-1H-pyrrole-2-carboxylic acid as a solid, which could be used in the next reaction without further purification. Yield: 64%; LCMS (retention time): 2.74 min (Method B); MS (ES+) gave m/z: 191 and 193.

References

[1] Patent: WO2006/123257, 2006, A2. Location in patent: Page/Page column 63
[2] Patent: WO2007/107319, 2007, A1. Location in patent: Page/Page column 7-8

4-BROMOPYRROLE-2-CARBOXYLIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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4-BROMOPYRROLE-2-CARBOXYLIC ACID Suppliers

China 117 Germany 1 India 1 Ukraine 1 United Kingdom 5 United States 14 Global 139

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View Lastest Price from 4-BROMOPYRROLE-2-CARBOXYLIC ACID manufacturers

Career Henan Chemical Co

Product: 4-BROMOPYRROLE-2-CARBOXYLIC ACID 27746-02-7
Price: US $1.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 100KG
Release date: 2018-12-25

27746-02-7, 4-BROMOPYRROLE-2-CARBOXYLIC ACIDRelated Search:

4-Bromopyrazole Pyrrole-2-carboxylic acid 4-Bromopyrazole-1-carboxylic acid tert-butyl ester Methyl 4-bromopyrrole-2-carboxylate 4-BROMOPYRROLE-2-CARBOXYLIC ACID METHYL 4-BROMO-1-METHYL-1H-PYRROLE-2-CARBOXYLATE METHYL 4,5-DIBROMO-1H-PYRROLE-2-CARBOXYLATE ETHYL 4-BROMO-3,5-DIMETHYL-1H-PYRROLE-2-CARBOXYLATE 4-BROMO-1-METHYL-1H-PYRROLE-2-CARBOXYLIC ACID 1-(tert-Butyl) 2-methyl 4-bromo-1H-pyrrole-1,2-dicarboxylate METHYL 4-BROMO-1-(PHENYLSULFONYL)-1H-PYRROLE-2-CARBOXYLATE 4,5-DIBROMO-1H-PYRROLE-2-CARBOXYLIC ACID 4-BROMO-PYRROLE-1,2-DICARBOXYLIC ACID 1-TERT-BUTYL ESTER 2-ETHYL ESTER ETHYL 4-BROMO-1H-PYRROLE-2-CARBOXYLATE METHYL 4-BROMO-1-[(5-CHLORO-2-METHOXYPHENYL)SULFONYL]-1H-PYRROLE-2-CARBOXYLATE 4-bromo-5-(chlorosulfonyl)-1H-pyrrole-2-carboxylic acid SPECS AQ-776/42801554 4,5-DIBROMO-1-METHYL-1H-PYRROLE-2-CARBOXYLIC ACID

4-BROMO-1H-PYRROLE-2-CARBOXYLIC ACID

4-BROMOPYRROLE-2-CARBOXYLIC ACID

RARECHEM AL BE 1264

4-bromo-1H-pyrrole-2-carboxylic acid(SALTDATA: FREE)

4-Bromo-1H-pyrrol-2-carboxylic acid

1H-Pyrrole-2-carboxylic acid, 4-bromo-

4-Bromo-1H-pyrrole-2-carboxylicaci

4-Bromo-1H-pyrrole-2-carboxylic acid, 95+%

27746-02-7

C5H4BrNO2

pharmacetical