ChemicalBook > CAS DataBase List > SB 221284

SB 221284

Product Name
SB 221284
CAS No.
196965-14-7
Chemical Name
SB 221284
Synonyms
SB 221284;5-(METHYLTHIO)-1-(3-PYRIDYLCARBAMOYL)-6-(TRIFLUOROMETHYL)INDOLINE;2,3-DIHYDRO-5-(METHYLTHIO)-N-3-PYRIDINYL-6-(TRIFLUOROMETHYL)-1H-INDOLE-1-CARBOXAMIDE;1H-Indole-1-carboxamide, 2,3-dihydro-5-(methylthio)-N-3-pyridinyl-6-(trifluoromethyl)-
CBNumber
CB4704933
Molecular Formula
C16H14F3N3OS
Formula Weight
353.36
MOL File
196965-14-7.mol
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SB 221284 Property

Melting point:
262-264 °C
Boiling point:
536.2±50.0 °C(Predicted)
Density 
1.43±0.1 g/cm3(Predicted)
storage temp. 
Store at +4°C
solubility 
DMSO: ~14 mg/mL, soluble
pka
13.13±0.20(Predicted)
form 
solid
color 
white
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Tocris
Product number
1379
Product name
SB221284
Purity
≥99%(HPLC)
Packaging
10
Price
$96
Updated
2021/12/16
Tocris
Product number
1379
Product name
SB221284
Purity
≥99%(HPLC)
Packaging
50
Price
$400
Updated
2021/12/16
TRC
Product number
S155028
Product name
SB221284
Packaging
5mg
Price
$170
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
BRS0000723
Product name
SB 221284
Purity
95.00%
Packaging
10MG
Price
$709.46
Updated
2021/12/16
ApexBio Technology
Product number
B6713
Product name
SB221284
Packaging
50mg
Price
$786
Updated
2021/12/16
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SB 221284 Chemical Properties,Usage,Production

Uses

SB 221284 is a potent, selective SR-2C/SR-2B antagonist.

Definition

ChEBI: SB 221284 is an indolyl carboxylic acid.

Biological Activity

Potent, selective 5-HT 2C/2B receptor antagonist. pK i values are 6.4, 7.9 and 8.6 for 5-HT 2A , 2B and 2C receptors respectively. Centrally active upon systemic administration in vivo .

SB 221284 Preparation Products And Raw materials

Raw materials

Preparation Products

196965-14-7, SB 221284Related Search:


  • 5-(METHYLTHIO)-1-(3-PYRIDYLCARBAMOYL)-6-(TRIFLUOROMETHYL)INDOLINE
  • 2,3-DIHYDRO-5-(METHYLTHIO)-N-3-PYRIDINYL-6-(TRIFLUOROMETHYL)-1H-INDOLE-1-CARBOXAMIDE
  • SB 221284
  • 1H-Indole-1-carboxamide, 2,3-dihydro-5-(methylthio)-N-3-pyridinyl-6-(trifluoromethyl)-
  • 196965-14-7
  • C16H14N3F3OS