Description References
ChemicalBook > CAS DataBase List > 3,4-Dimethylphenol

3,4-Dimethylphenol

Description References
Product Name
3,4-Dimethylphenol
CAS No.
95-65-8
Chemical Name
3,4-Dimethylphenol
Synonyms
3,4-XYLENOL;O-XYLENOL;1,3,4-Xylenol;Phenol,3,4-dimethyl-;3,4-DMP;NSC 1549;ai3-01552;FEMA 3596;o-4-Xylenol;as-o-xylenol
CBNumber
CB4723194
Molecular Formula
C8H10O
Formula Weight
122.16
MOL File
95-65-8.mol
More
Less

3,4-Dimethylphenol Property

Melting point:
65-68 °C
Boiling point:
227 °C(lit.)
Density 
1,138 g/cm3
vapor pressure 
0.475-130Pa at 25-66.2℃
refractive index 
1.5442
FEMA 
3596 | 3,4-XYLENOL
Flash point:
61 °C
storage temp. 
Store below +30°C.
solubility 
Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
pka
pK1:10.32 (25°C)
form 
Crystalline Powder
color 
Off-white to pale cream
Odor
DIMETHYLPHENOL slightly smoky and earthy character provides nice roasted notes to seafood, mushroom and coffee flavors.flat dry
Odor Type
dry
explosive limit
1.4%(V)
Water Solubility 
SLIGHTLY SOLUBLE
Merck 
14,10082
JECFA Number
708
BRN 
1099267
Exposure limits
ACGIH: TWA 1 ppm
InChIKey
YCOXTKKNXUZSKD-UHFFFAOYSA-N
LogP
2.23 at 25℃
CAS DataBase Reference
95-65-8(CAS DataBase Reference)
NIST Chemistry Reference
Phenol, 3,4-dimethyl-(95-65-8)
EPA Substance Registry System
3,4-Dimethylphenol (95-65-8)
More
Less

Safety

Hazard Codes 
T,N
Risk Statements 
24/25-34-51/53
Safety Statements 
26-36/37/39-45-61
RIDADR 
UN 2261 6.1/PG 2
WGK Germany 
3
RTECS 
ZE6300000
TSCA 
Yes
HazardClass 
6.1
PackingGroup 
II
HS Code 
29071400
Hazardous Substances Data
95-65-8(Hazardous Substances Data)
More
Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H314Causes severe skin burns and eye damage

H411Toxic to aquatic life with long lasting effects

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P273Avoid release to the environment.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More
Less

N-Bromosuccinimide Price

Sigma-Aldrich
Product number
D175404
Product name
3,4-Dimethylphenol
Purity
98%
Packaging
5g
Price
$26
Updated
2024/03/01
Sigma-Aldrich
Product number
D175404
Product name
3,4-Dimethylphenol
Purity
98%
Packaging
100g
Price
$67.1
Updated
2024/03/01
TCI Chemical
Product number
D0777
Product name
3,4-Dimethylphenol
Purity
>98.0%(GC)
Packaging
25g
Price
$17
Updated
2024/03/01
TCI Chemical
Product number
D0777
Product name
3,4-Dimethylphenol
Purity
>98.0%(GC)
Packaging
500g
Price
$180
Updated
2024/03/01
Alfa Aesar
Product number
A10599
Product name
3,4-Dimethylphenol
Purity
98+%
Packaging
100g
Price
$0
Updated
2021/12/16
More
Less

3,4-Dimethylphenol Chemical Properties,Usage,Production

Description

3,4-methylphenol (also 3,4-xylenol) has a flat, dry odor. It can be used as a flavoring agent without safety concern at current levels of intake. 3,4-dimethylphenol is used as an agent in the spectrophotometric method to determine nitrate in plants, soils, and water. It is also used to produce adhesive/sealant and resins as negative photoresist for electroplating.

References

[1] R. R. Elton-Bott, A modified spectrophotometric method for nitrate in plants, soils and water by nitration of 3,4-dimethylphenol, Analytica Chimica Acta, 1977, vol. 90, 215-221
[2] George A. Burdock, Fenaroli’s Handbook of Flavor Ingredients, Sixth Edition, 2010
[3] Chia L. Wang, John Davis, Bryan Lienke, Polyurethane systems having non-sag paintability and primerless adhesion on concrete, Patent, 2012
[4] Yasuo Masuda, Yasushi Washio, Koji Saito, Method of forming plated product using negative photoresist composition and photosensitive composition used therein, Patent, 2012

Chemical Properties

YELLOW TO BROWNISH CRYSTALLINE MASS

Occurrence

Reported found in coffee, tomato, parmesan and romano cheese, smoked fatty fish, white wine, katsuobushi (dried bonito) and wood vinegar.

Uses

Applications of 3,4-dimethylphenol:

  • It can react with ethyl cinnamates in trifluoroacetic acid to form the corresponding dihydrocoumarin derivatives.
  • Bromination of 3,4-dimethylphenol using bromine can lead to 6-bromo-3,4-dimethylphenol.
  • It can react with 1-fluoro-4-chloromethyl-1,4-diazoniabicyclo[2.2.2]octane bis(tetrafluoro-borate) (Selectfluor? F-TEDA-BF4) to form 4-fluoro-3,4-dimethylcyclohexa-2,5-dienone.

Definition

ChEBI: 3,4-xylenol is a member of the class of phenols that is phenol substituted by methyl groups at positions 3 and 4. It derives from a hydride of an o-xylene.

Aroma threshold values

Detection: 1.2 ppm

General Description

Colorless to light tan crystalline powder or solid. Odor threshold 1.2 mg/L. Taste threshold 0.05 mg/L.

Air & Water Reactions

Hygroscopic. Insoluble in water.

Reactivity Profile

3,4-Dimethylphenol is incompatible with bases, acid chlorides, acid anhydrides, and oxidizing agents. 3,4-Dimethylphenol corrodes steel, brass, copper, and copper alloys.

Fire Hazard

Flash point data for 3,4-Dimethylphenol are not available. 3,4-Dimethylphenol is probably combustible.

Purification Methods

Heat 3,4-xylenol with an equal weight of conc H2SO4 at 103-105o for 2-3hours, then dilute it with four volumes of water, reflux it for 1hour, and either steam distil or extract it repeatedly with diethyl ether after cooling to room temperature. The steam distillate is also extracted and evaporated to dryness. (The purification process depends on the much slower sulfonation of 3,4-dimethylphenol than most of its likely contaminants.). It can also be crystallised from water, hexane or pet ether, and sublimed in a vacuum. [Kester Ind Eng Chem (Anal Ed) 24 770 1932, Bernasconi & Paschalis J Am Chem Soc 108 29691986, Beilstein 6 IV 3099.]

3,4-Dimethylphenol Preparation Products And Raw materials

Raw materials

3,5-Dimethylphenol o-Xylene Phenol crude 2,6-Dimethylphenol COAL TAR Polishing oil Xylenol

Preparation Products

More
Less

3,4-Dimethylphenol Suppliers

Americas 1 Belgium 3 Canada 2 China 192 Europe 4 France 1 Germany 10 India 10 Italy 1 Japan 3 Norway 1 Russia 1 Slovakia 1 Sweden 1 Switzerland 4 The Netherlands 1 Ukraine 1 United Kingdom 14 United States 46 Global 297
HBCChem, Inc.
Tel
+1-510-219-6317
Fax
+1-650-486-1361
Email
sales@hbcchem.com
Country
United States
ProdList
10648
Advantage
60
Cato Research Chemicals Inc.
Tel
020-81215950 4000-868-328
Email
customer@uwalab.com
Country
United States
ProdList
10404
Advantage
58
Aladdin Scientific
Tel
+1-+1(833)-552-7181
Email
sales@aladdinsci.com
Country
United States
ProdList
57505
Advantage
58
Alfa Chemistry
Tel
--
Fax
--
Email
info@Alfa-Chemistry.com
Country
United States
ProdList
6814
Advantage
0
Frontier Scientific Services, Inc.
Tel
--
Fax
--
Email
customerservice@frontierssi.com
Country
United States
ProdList
1575
Advantage
0
CHEM-IS-TRY Inc.,
Tel
--
Fax
--
Country
United States
ProdList
190
Advantage
58
CBC America Corp. (part of CBC Group)
Tel
--
Fax
--
Email
chemsales@cbcamerica.com
Country
United States
ProdList
35
Advantage
58
TCI America, Inc. (Tokyo Chemical Industry Co., Ltd.)
Tel
--
Fax
--
Email
.Crew@tcichemicals.com
Country
United States
ProdList
3164
Advantage
58
Sasol North America Inc.
Tel
--
Fax
--
Email
reynaldo.rodriguez@us.sasol.com
Country
United States
ProdList
42
Advantage
58
Synerzine, Inc. (formerly Pyrazine Specialties, Inc. and CTC Organics)
Tel
--
Fax
--
Email
info@synerzine.com
Country
United States
ProdList
314
Advantage
58
VWR International, LLC.
Tel
--
Fax
--
Email
@sargentwelch.com
Country
United States
ProdList
6262
Advantage
58
Penta International Corporation
Tel
--
Fax
--
Email
lisaa@pentamfg.com
Country
United States
ProdList
5042
Advantage
58
WholeChem, LLC
Tel
--
Fax
--
Email
info@wholechem.com
Country
United States
ProdList
814
Advantage
58
Beijing Lys Chemicals Co, LTD.
Tel
--
Fax
--
Email
jiayanyong@lyschem.com
Country
United States
ProdList
710
Advantage
58
Lluch Essence S.L.
Tel
--
Fax
--
Email
web@lluche.com
Country
United States
ProdList
2352
Advantage
58
Firmenich Inc.
Tel
--
Fax
--
Email
Frederick.Keifer@firmenich.com
Country
United States
ProdList
1017
Advantage
58
Augustus Oils Ltd
Tel
--
Fax
--
Email
essentials@augustus-oils.ltd.uk
Country
United States
ProdList
1404
Advantage
58
Qingdao Free Trade Zone United International Co Ltd
Tel
--
Fax
--
Email
info@unitedint.com
Country
United States
ProdList
604
Advantage
58
M&U International LLC
Tel
--
Fax
--
Email
sales@mu-intel.com
Country
United States
ProdList
2011
Advantage
58
Pyrazine Specialties, Inc.
Tel
--
Fax
--
Country
United States
ProdList
1265
Advantage
30
TCI America
Tel
--
Fax
--
Email
sales@tciamerica.com
Country
United States
ProdList
6909
Advantage
75
Riedel-de Haen AG
Tel
--
Fax
--
Country
United States
ProdList
6773
Advantage
87
Frontier Scientific, Inc.
Tel
--
Fax
--
Email
sales@frontiersci.com
Country
United States
ProdList
6222
Advantage
86
Matrix Scientific
Tel
--
Fax
--
Email
sales@matrixscientific.com
Country
United States
ProdList
6632
Advantage
80
Snieckus Innovations
Tel
--
Fax
--
Email
info@snieckusinnovations.ca
Country
United States
ProdList
45
Advantage
50
Anvia Chemicals, LLC
Tel
--
Fax
--
Email
sales@anviachem.com
Country
United States
ProdList
3933
Advantage
0
HBCChem Inc.
Tel
--
Fax
--
Email
sales@hbcchem-inc.com
Country
United States
ProdList
4569
Advantage
30
Ivy Fine Chemicals
Tel
--
Fax
--
Email
sales@ivychem.com
Country
United States
ProdList
6493
Advantage
58
ChemService Inc.
Tel
--
Fax
--
Country
United States
ProdList
6379
Advantage
68
Advanced Synthesis Technologies
Tel
--
Fax
--
Email
sales@advancedsynthesis.com
Country
United States
ProdList
4775
Advantage
61
Penta Manufacturing Company
Tel
--
Fax
--
Email
sales@pentamfg.com
Country
United States
ProdList
5076
Advantage
65
CHEM-IS-TRY, Inc.
Tel
--
Fax
--
Email
sales@chem-is-try.com
Country
United States
ProdList
551
Advantage
56
AK Scientific, Inc.
Tel
--
Fax
--
Email
sales@aksci.com
Country
United States
ProdList
6347
Advantage
65
Alfa Aesar
Tel
--
Fax
--
Email
tech@alfa.com
Country
United States
ProdList
6814
Advantage
81
Waterstone Technology, LLC
Tel
--
Fax
--
Email
sales@waterstonetech.com
Country
United States
ProdList
6786
Advantage
30
3B Scientific Corporation
Tel
--
Fax
--
Email
sales@3bsc.com
Country
United States
ProdList
6718
Advantage
47
Wintersun Chemical
Tel
--
Fax
--
Email
purchasing@wintersunchem.com
Country
United States
ProdList
776
Advantage
68
Advance Scientific & Chemical
Tel
--
Fax
--
Email
sales@advance-scientific.com
Country
United States
ProdList
6419
Advantage
71
Nanjing Datang Chemicals Co.,Ltd.
Tel
--
Fax
--
Country
United States
ProdList
73
Advantage
38
ASDI Incorporated
Tel
--
Fax
--
Email
customerservice@asdi.net
Country
United States
ProdList
6922
Advantage
67
Spectrum Chemicals & Laboratory Products
Tel
--
Fax
--
Email
sales@spectrumchemical.com
Country
United States
ProdList
6699
Advantage
77
Crescent Chemical Co., Inc.
Tel
--
Fax
--
Email
sales@creschem.com
Country
United States
ProdList
4597
Advantage
68
ChemPacific Corporation
Tel
--
Fax
--
Email
sales@chempacific.com
Country
United States
ProdList
6891
Advantage
51
Eastern Chemical Corp.
Tel
--
Fax
--
Email
eastern@u-g.com
Country
United States
ProdList
2786
Advantage
34
City Chemicals Corporation
Tel
--
Fax
--
Country
United States
ProdList
6460
Advantage
72
Pfaltz & Bauer, Inc.
Tel
--
Fax
--
Email
sales@pfaltzandbauer.com
Country
United States
ProdList
6828
Advantage
72
More
Less

View Lastest Price from 3,4-Dimethylphenol manufacturers

Hebei Yanxi Chemical Co., Ltd.
Product
3,4-Dimethylphenol 95-65-8
Price
US $30.00-10.00/kg
Min. Order
1kg
Purity
0.99
Supply Ability
10 tons
Release date
2023-11-29
Hebei Mojin Biotechnology Co., Ltd
Product
3,4-Dimethylphenol 95-65-8
Price
US $0.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
50000KG/month
Release date
2023-11-24
NANJING PASTEUR ChEMICAL CO.,LTD
Product
3,4-Dimethylphenol 95-65-8
Price
US $0.00-0.00/kg
Min. Order
1000kg
Purity
99.9%
Supply Ability
5000 tons
Release date
2023-11-01

95-65-8, 3,4-DimethylphenolRelated Search:

Bromocresol green N,N-Dimethylacetamide CHLOROPHOSPHONAZO III Dimethyl sulfone XYLENOL ORANGE Dimethyl sulfoxide N,N-Dimethylformamide N,N-Dimethylaniline Poly(dimethylsiloxane) 2,6-Dimethylphenol, 99.8%,2,6-Dimethylphenol,99%,2,6-DIMETHYLPHENOL PESTANAL DIMETHYLPHENOL,2,4-(SG),2,4-DIMETHYLPHENOL(2,4-XYLENOL),2,4-DIMETHYLPHENOL, 1X1ML, MEOH, 5000UG/ ML,2,4-dimethylphenol solution Alizarin Complexone 2-HYDROXY-9-FLUORENONE Pcmx(4Chloro3,5Dimethylphenol),4Chloro3,5Dimethylphenol(Pcmx) Xylenol 2,5-Dimethylphenol, tech., 97%,2,5-DIMETHYLPHENOL, 99+%,2,5-Dimethylphenol,97%,2,5-DIMETHYLPHENOL/ GEMFIBROZIL 1,2,5,8-TETRAHYDROXYANTHRAQUINONE 3,5-Dimethylphenol,>98%,3,5-DIMETHYLPHENOL, 1000MG, NEAT,3,5-dimethylphenol solution

  • 1,2-Dimethyl-4-hydroxybenzene
  • 1,3,4-Xylenol
  • 3,4-dimethyl-pheno
  • 4,5-Dimethylphenol
  • 3 4-XYLENOL 98+%
  • 3,4-DIMETHYLPHENOL PESTANAL
  • 3,4-Dimethylphenol, 98+%
  • 3, 4-Xylenol (3,4-Dimethylphenol)
  • 3,4-DIMETHYLPHENOL / 3,4-XYLENOL
  • 3,4-Dimethylphenol, 4-Hydroxy-o-xylene
  • 3,4-Dimethylphenol,99%
  • 3,4-Dimethylphenol Standard
  • NSC 1549
  • 3,4-DiMethylphenol solution
  • 3,4-DiMethylphenol-d3,OD
  • 3,4-DIMETHYLPHENOL FOR SYNTHESIS
  • 3,4-DiMethylphenol, 99% 100GR
  • 3,4-Xylenol, 4-Hydroxy-o-xylene
  • 3.4-DiMethylph
  • 3,4-DiMethhylphenol
  • 3,4-Xylenol (OH=1)
  • 3,4-DIMETHYLPHENOL
  • 3,4-DMP
  • 4-Hydroxy-1,2-dimethylbenzene
  • ai3-01552
  • as-o-xylenol
  • o-4-Xylenol
  • Phenol,3,4-dimethyl-
  • O-XYLENOL
  • FEMA 3596
  • ASYM-O-XYLENOL
  • 1-HYDROXY-3,4-DIMETHYLBENZENE
  • 3,4-XYLENOL
  • 4-HYDROXY-O-XYLENE
  • 3,4-DimethylphenolSolution,2000mg/L,1ml
  • 3,4-Dimethylphenol &gt
  • 3,4-Dimethylphenol ISO 9001：2015 REACH
  • TIANFU-CHEM CAS:95-65-8 3,4-Dimethylphenol
  • Metacresol EP Impurity L
  • 3,4-Dimethylphenol 100 μg/ml Methanol
  • XA12734000ME3,4-DimethylphenoL100μg/mLin Met
  • 95-65-8
  • 576-21-1
  • 95658
  • 108952
  • Organic Building Blocks
  • Phenols
  • Oxygen Compounds
  • Building Blocks
  • Aromatics
  • Aromatic Phenols
  • Industrial/Fine Chemicals