ChemicalBook > CAS DataBase List > Althiazide
Althiazide
- Product Name
- Althiazide
- CAS No.
- 5588-16-9
- Chemical Name
- Althiazide
- Synonyms
- P-1779;Altizid;CB 8093;CB-8093;Althizide;ALTHIAZIDE;Altizide CRS;Altizide (Y0000606);3-[(Allylthio)methyl]-6-chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide;3-[(allylthio)methyl]-6-chloro-1,1-diketo-3,4-dihydro-2H-benzo[e][1,2,4]thiadiazine-7-sulfonamide
- CBNumber
- CB4739720
- Molecular Formula
- C11H14ClN3O4S3
- Formula Weight
- 383.89
- MOL File
- 5588-16-9.mol
More
Less
Althiazide Property
- Melting point:
- 206-207°
- Boiling point:
- 625.8±65.0 °C(Predicted)
- Density
- 1.502±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- Practically insoluble in water, soluble in methanol, practically insoluble in dichloromethane.
- pka
- 8.33±0.40(Predicted)
- color
- White to Off-White
- EPA Substance Registry System
- 2H-1,2,4-Benzothiadiazine-7-sulfonamide, 6-chloro-3,4-dihydro-3-[(2-propen-1-ylthio)methyl]-, 1,1-dioxide (5588-16-9)
More
Less
Safety
- WGK Germany
- 3
More
Less
N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- Y0000606
- Product name
- Altizide
- Purity
- European Pharmacopoeia (EP) Reference Standard
- Packaging
- y0000606
- Price
- $220
- Updated
- 2024/03/01
Usbiological
- Product number
- 259084
- Product name
- Althiazide
- Packaging
- 5mg
- Price
- $446
- Updated
- 2021/12/16
TRC
- Product number
- A575775
- Product name
- Althiazide
- Packaging
- 50mg
- Price
- $790
- Updated
- 2021/12/16
American Custom Chemicals Corporation
- Product number
- API0007933
- Product name
- ALTHIAZIDE
- Purity
- 95.00%
- Packaging
- 100MG
- Price
- $1871.1
- Updated
- 2021/12/16
Biosynth Carbosynth
- Product number
- FA17332
- Product name
- Althiazide
- Packaging
- 25mg
- Price
- $625
- Updated
- 2021/12/16
More
Less
Althiazide Chemical Properties,Usage,Production
Description
Althiazide, also known as altizide, is an agent belonging to the class of thiazide diuretics with antihypertensive activity. This aldosterone antagonist is often combined with spironolactone.
Chemical Properties
White Solid
Originator
Althiazide,Solchem
Uses
Diuretic and antihypertensive.
Definition
ChEBI: Althiazide is a benzothiadiazine. It is the thiazide and sulfonamide derivative.
Manufacturing Process
To 6.75 g (0.0225 mole) of 4-amino-2-chloro-5-(methylsulfamyl) benzenesulfonamide in 45 ml of dimethylformamide is added 4.86 g (0.03 mole) of dimethyl allylmercaptoacetal followed by 1.5 ml ethyl acetate saturated with hydrogen chloride gas. The solution is refluxed for 1.5 hours, cooled and added dropwise with stirring to ice/water. The resulting precipitate is filtered, dried and recrystallized from isopropanol. The recrystallization gave 4.0 g of 2-methyl-3-allylthiomethyl-6-chloro-7-sulfamyl-3,4-dihydro-1,2,4- benzothiadiazine-1,1-dioxide; M.P. 168.5-170°C.
Therapeutic Function
Diuretic, Antihypertensive
Althiazide Preparation Products And Raw materials
Raw materials
Preparation Products
More
Less
Althiazide Suppliers
- Tel
- --
- Fax
- --
- @pharmaffiliates.com
- Country
- India
- ProdList
- 6754
- Advantage
- 58
- Tel
- --
- Fax
- --
- standards@synzeal.com
- Country
- India
- ProdList
- 6514
- Advantage
- 58
- Tel
- --
- Fax
- --
- mktg@pharmaffiliates.com
- Country
- India
- ProdList
- 6739
- Advantage
- 58
More
Less
View Lastest Price from Althiazide manufacturers
Shaanxi Dideu Medichem Co. Ltd
- Product
- Althiazide 5588-16-9
- Price
- US $0.00-0.00/KG
- Min. Order
- 1KG
- Purity
- 99.0%
- Supply Ability
- 1000kg
- Release date
- 2024-08-01
5588-16-9, AlthiazideRelated Search:
o-Chlorobenzenesulfonamide
Benzenesulfonamide, 2-(methylamino)- (9CI)
4-Chloro-N-methylbenzenesulphonamide
Althiazide
Hydrochlorothiazide
2-Aminobenzenesulfonamide
4-Chlorobenzenesulfonamide
CLOFENAMIDE
4-Amino-6-chlorobenzene-1,3-disulfonamide
Methalthiazide
2-AMINO-N-METHYLBENZENESULFONAMIDE
4-CHLORO-1,3-BENZENEDITHIOL