2-AMINO-N-METHYLBENZENESULFONAMIDE

Product Name: 2-AMINO-N-METHYLBENZENESULFONAMIDE
CAS No.: 16288-77-0
Chemical Name: 2-AMINO-N-METHYLBENZENESULFONAMIDE
Synonyms: N-Methyl-2-aminobenzenesulfonamide;2-AMINO-N-METHYLBENZENESULFONAMIDE;BenzenesulfonaMide, 2-aMino-N-Methyl-;2-aMino-N-Methylbenzene-1-sulfonaMide;2-amino-N-methylbenzenesulfonamide(SALTDATA: HCl)
CBNumber: CB2191047
Molecular Formula: C7H10N2O2S
Formula Weight: 186.23
MOL File: 16288-77-0.mol

More

Less

2-AMINO-N-METHYLBENZENESULFONAMIDE Property

Melting point:: 59-60℃
Boiling point:: 352.9±44.0 °C(Predicted)
Density: 1.308
storage temp.: 2-8°C(protect from light)
pka: 11?+-.0.10(Predicted)
Appearance: Light yellow to brown Solid

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

TRC

Product number: A634700
Product name: 2-Amino-N-methylbenzenesulfonamide
Packaging: 10mg
Price: $45
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FA153547
Product name: 2-Amino-N-methylbenzenesulfonamide
Packaging: 1g
Price: $80
Updated: 2021/12/16

ChemScene

Product number: CS-M2487
Product name: Benzenesulfonamide,2-amino-N-methyl-
Purity: >97.0%
Packaging: 5g
Price: $98
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FA153547
Product name: 2-Amino-N-methylbenzenesulfonamide
Packaging: 2g
Price: $100
Updated: 2021/12/16

AK Scientific

Product number: W3551
Product name: 2-Amino-N-methylbenzenesulfonamide
Packaging: 5g
Price: $169
Updated: 2021/12/16

More

Less

2-AMINO-N-METHYLBENZENESULFONAMIDE Chemical Properties,Usage,Production

Description

2-Amino-N-methylbenzenesulfonamide is obtained by treating 2-nitrobenzenesulfonyl chloride with methylamine and subsequent reduction. Used as a dye component. The amides of 2-aminobenzenesulfonic acid can be treated with aldehydes or orthoformic acid esters to give 1,2,4-benzothiadiazine 1,1-dioxides or their dihydro compounds; these substances have been proposed as diuretics.

Synthesis

23530-40-7

16288-77-0

Step B / Intermediate C4: Synthesis of 2-amino-N-methylbenzenesulfonamide To a solution of N-methyl-2-nitrobenzenesulfonamide (26 g, 0.12 mol) in methanol (500 mL) was added 10% palladium carbon catalyst (2 g). The reaction mixture was stirred at room temperature under hydrogen atmosphere for 3 hours. Upon completion of the reaction, the catalyst was removed by filtration and the filtrate was concentrated under reduced pressure to afford the target product 2-amino-N-methylbenzenesulfonamide (22 g, 98% yield). The structure of the product was confirmed by 1H NMR (400 MHz, CDCl3): δ 7.45-7.48 (dd, 1H, J=1.6 Hz, 8.0 Hz), 7.24-7.31 (m, 2H), 6.81-6.83 (dd, 1H, J=0.6 Hz, 8.0 Hz), 6.60-6.65 (m, 1H), 5.89 (s 2H), 2.370-2.374 (d, 3H, J=1.6Hz).

References

[1] Patent: WO2012/92880, 2012, A1. Location in patent: Page/Page column 64
[2] Angewandte Chemie - International Edition, 2010, vol. 49, # 29, p. 4955 - 4957
[3] Patent: WO2007/45868, 2007, A1. Location in patent: Page/Page column 47
[4] Farmaco, Edizione Scientifica, 1954, vol. 9, p. 661,678, 680
[5] Farmaco, Edizione Scientifica, 1957, vol. 12, p. 495,499, 500

2-AMINO-N-METHYLBENZENESULFONAMIDE Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

2-AMINO-N-METHYLBENZENESULFONAMIDE Suppliers

China 50 India 1 Switzerland 1 Ukraine 1 United Kingdom 2 United States 8 Global 63

J & K SCIENTIFIC LTD.

Tel: 18210857532; 18210857532
Fax: 86-10-82849933
Email: jkinfo@jkchemical.com
Country: China
ProdList: 96815
Advantage: 76

Adamas Reagent, Ltd.

Tel: 400-6009262 16621234537
Fax: 021-64823266
Email: chenyj@titansci.com
Country: China
ProdList: 14101
Advantage: 59

Atop-Pharma (Shanghai) Technology Co., Ltd.

Tel: +86 (21) 5196-9732
Fax: +86 (21) 5196-9733
Country: China
ProdList: 996
Advantage: 57

Chengdu Forest Science and Technology Development Co., Ltd.

Tel: 18030648795
Fax: 028-61777050
Email: sales@cdforestchem.com
Country: China
ProdList: 1998
Advantage: 58

Nanjing Norris-Pharm Technology Co., Ltd

Tel: 18652989687
Fax: +86-25-52131256
Email: sales@norris-pharm.com
Country: China
ProdList: 8878
Advantage: 55

Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.

Tel: 025-66113011 17798518460
Fax: (1)02557626880
Email: cfzhang@aikonchem.com
Country: China
ProdList: 19913
Advantage: 55

Haoyuan Chemexpress Co., Ltd.

Tel: 021-58950125
Fax: (86) 21-58955996
Email: info@chemexpress.com
Country: China
ProdList: 7552
Advantage: 61

Shanghai Keepontech Co.,Ltd

Tel: 021-54849683 13601642561
Fax: +86-21-54375689
Email: sales@keepontech.com
Country: China
ProdList: 998
Advantage: 59

9ding chemical ( Shanghai) Limited

Tel: 4009209199
Fax: 86-021-52271987
Email: sales@9dingchem.com
Country: China
ProdList: 18209
Advantage: 56

Shanghai Witofly Chemical Co.,Ltd

Tel
Email: sales@witofly.com
Country: China
ProdList: 2864
Advantage: 52

More

Less

View Lastest Price from 2-AMINO-N-METHYLBENZENESULFONAMIDE manufacturers

Career Henan Chemical Co

Product: 2-AMINO-N-METHYLBENZENESULFONAMIDE 16288-77-0
Price: US $1.00/g
Min. Order: 1g
Purity: 99.0%
Supply Ability: 100kg
Release date: 2020-01-10

16288-77-0, 2-AMINO-N-METHYLBENZENESULFONAMIDERelated Search:

Chlorothiazide CYCLOTHIAZIDE DIAZOXIDE Althiazide HYDROFLUMETHIAZIDE Hydrochlorothiazide 2-Amino-N-ethylbenzenesulfonanilide POLYTHIAZIDE (200 MG) Trichlormethiazide BENDROFLUMETHIAZIDE BENZTHIAZIDE 7-(DIMETHYLAMINOSULPHONYL)-2,3-DIHYDRO-1-[[N-(2-METHOXYPHENYL)AMINO]CARBONYL]-(1H)-INDOLE (2-INDOL-3-YLETHYL)((2-NITROPHENYL)SULFONYL)AMINE 1-((4-(3-CHLORO-5-(TRIFLUOROMETHYL)(2-PYRIDYL))PIPERAZINYL)SULFONYL)-2-NITROBENZENE 2-NITRO-1-((4-(5-(TRIFLUOROMETHYL)(2-PYRIDYL))PIPERAZINYL)SULFONYL)BENZENE 2,3-DIHYDRO-N,N-DIMETHYL-7-(1H)-INDOLESULPHONAMIDE 2-AMINO-N-QUINOLIN-8-YL-BENZENESULFONAMIDE 1-[(ETHYLAMINO)CARBONYL]-7-(DIMETHYLAMINOSULPHONYL)-2,3-DIHYDRO-(1H)-INDOLE

2-amino-N-methylbenzenesulfonamide(SALTDATA: HCl)

N-Methyl-2-aminobenzenesulfonamide

2-aMino-N-Methylbenzene-1-sulfonaMide

BenzenesulfonaMide, 2-aMino-N-Methyl-

2-AMINO-N-METHYLBENZENESULFONAMIDE

16288-77-0