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NEUROMEDIN U (RAT)

Product Name
NEUROMEDIN U (RAT)
CAS No.
117505-80-3
Chemical Name
NEUROMEDIN U (RAT)
Synonyms
NMU-23;NMU, RAT;neuromedin U;NMU-23 (RAT);neuromedin U-23;NEUROMEDIN U (RAT);Rat neuromedin U-23;YKVNEYQGPVAPSGGFFLFRPRN-NH2;NeuroMedin U-23 (rat) NMU-23;H-Tyr-Lys-Val-Asn-Glu-Tyr-Gln-Gly-Pro-Val-Ala-Pro-Ser-
CBNumber
CB4741505
Molecular Formula
C124H180N34O31
Formula Weight
2642.97
MOL File
117505-80-3.mol
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NEUROMEDIN U (RAT) Property

storage temp. 
−20°C
form 
lyophilized powder
Water Solubility 
Soluble to 1 mg/ml in Water
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Safety

Safety Statements 
22-24/25
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Alfa Aesar
Product number
J66682
Product name
Neuromedin U, rat
Packaging
0.5mg
Price
$135
Updated
2021/12/16
Alfa Aesar
Product number
J66682
Product name
Neuromedin U, rat
Packaging
1mg
Price
$240
Updated
2021/12/16
Usbiological
Product number
N2171-80Q
Product name
Neuromedin U
Packaging
1mg
Price
$531
Updated
2021/12/16
Usbiological
Product number
N2171-80P
Product name
Neuromedin U
Packaging
100ug
Price
$715
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
PEP0002607
Product name
NEUROMEDIN U, RAT
Purity
95.00%
Packaging
2MG
Price
$759.07
Updated
2021/12/16
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NEUROMEDIN U (RAT) Chemical Properties,Usage,Production

Biological Activity

Neuromedin U, rat is a 23 amino acid brain-gut peptide that regulates several important physiological functions including energy balance, stress response and nociception through its cognate receptor NMUR2 in the central nervous system.

in vitro

To establish an electrochemiluminescent (ECL) binding assay for NMUR2 receptor, the peptide Neuromedin U (NMU-23) is labeled at the N terminus with Ru(bpy) 2+ 3 and allowed to bind to the human NMUR2 receptor in the cell membranes immobilized on the electrode on the bottom of each assay plate. Upon application of an electric current, the receptor-bound Ru(bpy) 2 + 3 -ligand undergoes an oxidation-reduction cycle in the presence of a coreactant tripropylamine and emits light. Signal is only generated when the Ru(bpy) 2+ 3 label is in proximity to the electrode, thus discriminating the bound label from the unbound and enabling a no wash, homogenous assay format. The ECL-based NMUR2 binding assay is used to screen our corporate compound collection . Approximately 670,000 compounds with diverse structures are tested at 10 μM for their ability to displace the binding of 0.5 nM Ru(bpy) 2+ 3 -NMU-23 to human NMUR2 receptors. From binding experiments, the K i values for NMU-23 is determined to be 4.7 nM.

target

NMUR2

NEUROMEDIN U (RAT) Preparation Products And Raw materials

Raw materials

Preparation Products

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NEUROMEDIN U (RAT) Suppliers

China 74 Germany 2 Japan 2 Switzerland 1 United Kingdom 1 United States 15 Global 95
Tocris Bioscience
Tel
--
Fax
--
Email
customerservice@tocris.co.uk
Country
United Kingdom
ProdList
5726
Advantage
77

117505-80-3, NEUROMEDIN U (RAT)Related Search:

NEUROMEDIN N (RAT, MOUSE, PORCINE, CANINE) ANTI-NEUROMEDIN S (RAT) NEUROMEDIN S (RAT) BIOTINYL-NEUROMEDIN S (RAT) NEUROMEDIN U (RAT)

  • neuromedin U-23
  • NEUROMEDIN U (RAT)
  • NMU-23 (RAT)
  • NMU, RAT
  • YKVNEYQGPVAPSGGFFLFRPRN-NH2
  • TYR-LYS-VAL-ASN-GLU-TYR-GLN-GLY-PRO-VAL-ALA-PRO-SER-GLY-GLY-PHE-PHE-LEU-PHE-ARG-PRO-ARG-ASN-NH2
  • H-TYR-LYS-VAL-ASN-GLU-TYR-GLN-GLY-PRO-VAL-ALA-PRO-SER-GLY-GLY-PHE-PHE-LEU-PHE-ARG-PRO-ARG-ASN-NH2
  • neuromedin U
  • H-Tyr-Lys-Val-Asn-Glu-Tyr-Gln-Gly-Pro-Val-Ala-Pro-Ser-
  • L-Tyr-L-Lys-L-Val-L-Asn-L-Glu-L-Tyr-L-Gln-Gly-L-Pro-L-Val-L-Ala-L-Pro-L-Ser-Gly-Gly-L-Phe-L-Phe-L-Leu-L-Phe-L-Arg-L-Pro-L-Arg-L-Asn-NH2
  • Neuromedin U 25 (pig spinal cord), 1-L-tyrosine-4-L-asparagine-6-L-tyrosine-7-de-L-phenylalanine-11-de-L-isoleucine-13-L-alanine-14-L-proline-15-L-serine-16-glycine-17-glycine-18-L-phenylalanine-
  • NeuroMedin U-23 (rat) NMU-23
  • NMU-23
  • Rat neuromedin U-23
  • L-Aspartamide, L-tyrosyl-L-lysyl-L-valyl-L-asparaginyl-L-α-glutamyl-L-tyrosyl-L-glutaminylglycyl-L-prolyl-L-valyl-L-alanyl-L-prolyl-L-serylglycylglycyl-L-phenylalanyl-L-phenylalanyl-L-leucyl-L-phenylalanyl-L-arginyl-L-prolyl-L-arginyl-
  • L-Tyrosyl-L-lysyl-L-valyl-L-asparaginyl-L-α-glutamyl-L-tyrosyl-L-glutaminylglycyl-L-prolyl-L-valyl-L-alanyl-L-prolyl-L-serylglycylglycyl-L-phenylalanyl-L-phenylalanyl-L-leucyl-L-phenylalanyl-L-arginyl-L-prolyl-L-arginyl-L-aspartamide
  • 117505-80-3
  • C124H180N34O31
  • Peptide