2-CHLORO-5-FLUOROANISOLE

Product Name: 2-CHLORO-5-FLUOROANISOLE
CAS No.: 450-89-5
Chemical Name: 2-CHLORO-5-FLUOROANISOLE
Synonyms: 2-Chloro-5-flouroanisole;2-CHLORO-5-FLUOROANISOLE;2-Chloro-5-fluoroanisole98%;2-Chloro-5-fluoroanisole >2-Chloro-5-fluoroanisole,97%;2-Chloro-5-fluoroanisole 98%;1-CHLORO-4-FLUORO-2-METHOXYBENZENE;1-Chloro-2-methoxy-4-fluorobenzene;Benzene, 1-chloro-4-fluoro-2-methoxy-;2-CHLORO-5-FLUOROANISOLE ISO 9001：2015 REACH
CBNumber: CB4753153
Molecular Formula: C7H6ClFO
Formula Weight: 160.57
MOL File: 450-89-5.mol

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2-CHLORO-5-FLUOROANISOLE Property

Boiling point:: 195 °C / 757mmHg
Density: 1.28
refractive index: 1.519
storage temp.: Sealed in dry,Room Temperature
form: Liquid
color: Clear colorless
CAS DataBase Reference: 450-89-5(CAS DataBase Reference)

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Safety

Hazard Codes: Xi
Risk Statements: 10-36/37/38-36/38
Safety Statements: 16-26-36-37/39-35-28-15-3/9
RIDADR: 1993
Hazard Note: Irritant
HS Code: 29093090

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H227Combustible liquid

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P403+P235Store in a well-ventilated place. Keep cool.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

TCI Chemical

Product number: C2216
Product name: 2-Chloro-5-fluoroanisole
Purity: >97.0%(GC)
Packaging: 5g
Price: $65
Updated: 2025/07/31

TRC

Product number: C585860
Product name: 2-Chloro-5-fluoroanisole
Packaging: 50mg
Price: $60
Updated: 2021/12/16

Oakwood

Product number: 004419
Product name: 2-Chloro-5-fluoroanisole
Purity: 98%
Packaging: 1g
Price: $14
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC33586
Product name: 2-Chloro-5-fluoroanisole
Packaging: 2g
Price: $44
Updated: 2021/12/16

Biosynth Carbosynth

Product number: FC33586
Product name: 2-Chloro-5-fluoroanisole
Packaging: 5G
Price: $80
Updated: 2021/12/16

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2-CHLORO-5-FLUOROANISOLE Chemical Properties,Usage,Production

Chemical Properties

CLEAR COLOURLESS LIQUID

Synthesis

3827-49-4

74-88-4

450-89-5

To a solution of 2-chloro-5-fluorophenol (959 mg, 6.54 mmol) in N,N-dimethylformamide (DMF, 15 mL) was added 60% sodium hydride (NaH, 496 mg, 12.4 mmol) in batches at 0 °C. After the hydrogen bubbling stopped, iodomethane (0.43 mL, 6.91 mmol) was added and the reaction mixture was stirred at room temperature overnight. Upon completion of the reaction, the mixture was slowly poured into a beaker containing water and crushed ice, alkalized with saturated aqueous sodium bicarbonate (NaHCO3) and extracted with dichloromethane (DCM). The organic phases were combined, washed with brine, dried over anhydrous sodium sulfate (Na2SO4) and concentrated under reduced pressure. The crude product was purified by silica gel column chromatography using hexane:ethyl acetate (9:1) as eluent to afford 1-chloro-4-fluoro-2-methoxybenzene (600 mg) as a colorless oil. High performance liquid chromatography (HPLC, 254 nm) retention time (Rt): 6.15 min. 1H nuclear magnetic resonance (NMR, 600 MHz, DMSO-d6) δ ppm: 3.86 (s, 3H), 6.76-6.85 (m, 1H), 7.10 (dd, J = 10.90, 2.84 Hz, 1H), 7.45 (dd, J = 8.70, 6.14 Hz, 1H).

References

[1] Patent: WO2017/220477, 2017, A1. Location in patent: Page/Page column 33

2-CHLORO-5-FLUOROANISOLE Preparation Products And Raw materials

Raw materials

Preparation Products

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2-CHLORO-5-FLUOROANISOLE Suppliers

Americas 1 Belgium 1 China 90 Europe 1 France 1 Germany 2 India 2 Italy 1 Japan 3 United Kingdom 8 United States 14 Global 124

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View Lastest Price from 2-CHLORO-5-FLUOROANISOLE manufacturers

Career Henan Chemical Co

Product: 2-CHLORO-5-FLUOROANISOLE 450-89-5
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 100KG
Release date: 2020-01-09

450-89-5, 2-CHLORO-5-FLUOROANISOLERelated Search:

2-CHLORO-5-FLUOROANISOLE 2-CHLORO-3,5-DIFLUOROANISOLE 2-BROMO-6-CHLORO-4-FLUOROANISOLE 2-BROMO-4-CHLORO-6-FLUOROANISOLE 3-CHLORO-4-FLUOROANISOLE,3-Chloro-4-fluoroanisole 98%,3-Chloro-4-fluoroanisole98% 3-CHLORO-2-FLUOROANISOLE 3-CHLORO-5-FLUOROANISOLE, 96.0%(GC),3-CHLORO-5-FLUOROANISOLE 4-CHLORO-3-FLUOROANISOLE,4-Chloro-3-fluoroanisole 98%,4-Chloro-3-fluoroanisole98% 5-BROMO-2-CHLORO-4-FLUOROANISOLE 2-CHLORO-4-FLUOROANISOLE,2-Chloro-4-fluoroanisole 98%,2-Chloro-4-fluoroanisole98% 4-BROMO-2-CHLORO-6-FLUOROANISOLE NOVIFLUMURON 5-CHLORO-2-FLUORO-4-METHOXYPHENYLBORONIC ACID N-[2-(2-CHLORO-5-FLUOROPHENOXY)ETHYL]-N-METHYLAMINE 2-CHLORO-5-FLUOROPHENETOLE 5-CHLORO-2-FLUOROANISOLE 4-Chloro-2-fluoroanisole98%,4-Chloro-2-fluoroanisole 98%,4-CHLORO-2-FLUOROANISOLE 2-CHLORO-6-FLUOROANISOLE

1-CHLORO-4-FLUORO-2-METHOXYBENZENE

2-CHLORO-5-FLUOROANISOLE

2-Chloro-5-fluoroanisole 98%

2-Chloro-5-fluoroanisole98%

1-Chloro-2-methoxy-4-fluorobenzene

2-Chloro-5-fluoroanisole,97%

2-Chloro-5-fluoroanisole1-Chloro-4-fluoro-2-methoxybenzene

2-Chloro-5-flouroanisole

1-Chloro-4-fluoro-2-methoxybenzene, 2-Chloro-5-fluorophenyl methyl ether

2-Chloro-5-fluoroanisole &gt

Benzene, 1-chloro-4-fluoro-2-methoxy-

2-CHLORO-5-FLUOROANISOLE ISO 9001：2015 REACH

450-89-5

Anisole

Anisoles, Alkyloxy Compounds & Phenylacetates

Chlorine Compounds

Fluorine Compounds