ChemicalBook > CAS DataBase List > Flumethasone 21-pivalate

Flumethasone 21-pivalate

Product Name: Flumethasone 21-pivalate
CAS No.: 2002-29-1
Chemical Name: Flumethasone 21-pivalate
Synonyms: Losalen;Lorinden;locorten;locacorten;NSC 107680;21-pivalate;FLUMETHSONEPIVALATE;FLUMETHASONE PIVALATE;Flumethasome pivalate;flumetasone 21-pivalate
CBNumber: CB4762018
Molecular Formula: C27H36F2O6
Formula Weight: 494.57
MOL File: 2002-29-1.mol

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Flumethasone 21-pivalate Property

Melting point:: >263°C (dec.)
Boiling point:: 600.3±55.0 °C(Predicted)
Density: 1.27±0.1 g/cm3(Predicted)
storage temp.: Refrigerator
solubility: dioxane: soluble4.0ML, clear, colorless to very faintly yellow (50 mg + 4.0 mL dioxane)
form: solid
pka: 11.86±0.70(Predicted)
color: White to Off-White
optical activity: [α]25/D 71.0 to 82.0°, c = 1 in dioxane
CAS DataBase Reference: 2002-29-1(CAS DataBase Reference)
EPA Substance Registry System: Flumethasone-21-pivalate (2002-29-1)

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Safety

Hazard Codes: Xn
Risk Statements: 40
Safety Statements: 22-36
WGK Germany: 3
RTECS: TU3832010
HS Code: 2937220000
Toxicity: mouse,LD50,oral,> 5gm/kg (5000mg/kg),Drugs in Japan Vol. 6, Pg. 705, 1982.

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H351Suspected of causing cancer

Precautionary statements

P201Obtain special instructions before use.

P202Do not handle until all safety precautions have been read and understood.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P308+P313IF exposed or concerned: Get medical advice/attention.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: F0188500
Product name: Flumethasone pivalate
Purity: European Pharmacopoeia (EP) Reference Standard
Packaging: 100 mg
Price: $156
Updated: 2025/07/31

Sigma-Aldrich

Product number: F0891
Product name: Flumethasone pivalate
Packaging: 100mg
Price: $177
Updated: 2023/06/20

Sigma-Aldrich

Product number: F0188500
Product name: Flumethasone pivalate
Purity: European Pharmacopoeia (EP) Reference Standard
Packaging: f0188500
Price: $153
Updated: 2024/03/01

TRC

Product number: F455015
Product name: Flumethasone21-Pivalate
Packaging: 10mg
Price: $65
Updated: 2021/12/16

TRC

Product number: F455015
Product name: Flumethasone21-Pivalate
Packaging: 50mg
Price: $110
Updated: 2021/12/16

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Flumethasone 21-pivalate Chemical Properties,Usage,Production

Chemical Properties

White or almost white, crystalline powder.

Uses

An anti-inflammatory anti-itching corticosteroid found in topical creams.

Uses

flumethasone pivalate is a moderately potent difluorinated corticosteroid ester with anti-inflammatory, antipruritic and vasoconstrictive properties. As it is a pivalate, its anti-inflammatory action is concentrated at the site of application. This local effect on diseased areas results in a prompt decrease in inflammation, exudation and itching.

Definition

ChEBI: Flumethasone pivalate is a pivalate ester, a glucocorticoid, an 11beta-hydroxy steroid, a 17alpha-hydroxy steroid, a 20-oxo steroid, a fluorinated steroid, a 3-oxo-Delta(1),Delta(4)-steroid and a tertiary alpha-hydroxy ketone. It has a role as an anti-inflammatory drug and an antipruritic drug. It is functionally related to a flumethasone.

brand name

Locorten (Novartis).

Flumethasone 21-pivalate Preparation Products And Raw materials

Raw materials

Preparation Products

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Flumethasone 21-pivalate Suppliers

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View Lastest Price from Flumethasone 21-pivalate manufacturers

Shaanxi TNJONE Pharmaceutical Co., Ltd

Product: Flumethasone Pivalate 2002-29-1
Price: US $0.00/kg
Min. Order: 1kg
Purity: 99%
Supply Ability: 20tons
Release date: 2024-04-25

2002-29-1, Flumethasone 21-pivalateRelated Search:

MAGNESIUM DIPROPYLACETATE HYDRATE Methyl acrylate Estradiol valerate Methyl trimethylacetate Methylparaben Bensulfuron methyl 2-Methylbutyl acetate Dexamethasone Glycidyl tertcarbonate Pivalic acid Flumethasone 4-tert-Butylcyclohexyl acetate Prednisolone Kresoxim-methyl Thiophanate-methyl Methyl Parathion-methyl Isoflupredone

21-pivalate

locacorten

flumethasone 21-pivalate

FLUMETHASONE PIVALATE

6a,9a-difluoro-16a-methyl-prednisolone-21-pivalate

6ALPHA,9-DIFLUORO-11BETA,17,21-TRIHYDROXY-16ALPHA-METHYLPREGNA-1,4-DIENE-3,20-DIONE 21-[2,2-DIMETHYLPROPIONATE]

Pregna-1,4-diene-3,20-dione, 21-(2,2-dimethyl-1-oxopropoxy)-6,9-difluoro-11,17-dihydroxy-16-methyl-, (6.alpha.,11.beta.,16.alpha.)-

6α,9-difluoro-11β,17,21-trihydroxy-16α-methylpregna-1,4-diene-3,20-dione 21-(2,2-dimethylpropionate)

6α,9α-Difluoro-11β,17α,21-trihydroxy-16α-methyl-1,4-pregnadiene-3,20-dione 21-pivalate

6α,9α-Difluoro-16α-methylprednisolone 21-pivalate

Lorinden

Losalen

NSC 107680

Pivalic acid, 21-ester with 6α,9-difluoro-11β,17,21-trihydroxy-16α-methylpregna-1,4-diene-3,20-dione (8CI)

Pregna-1,4-diene-3,20-dione, 21-(2,2-dimethyl-1-oxopropoxy)-6,9-difluoro-11,17-dihydroxy-16-methyl-, (6α,11β,16α)-

Pregna-1,4-diene-3,20-dione, 6α,9-difluoro-11β,17,21-trihydroxy-16α-methyl-, 21-pivalate (7CI, 8CI)

locorten

pregna-1,4-diene-3,20-dione,6-alpha,9-difluoro-11-beta,17,21-trihydroxy-16-alp

flumetasone 21-pivalate

Flumethasome pivalate

Flumethasone Pivalate (200 mg)

FLUMETHSONEPIVALATE

(6α,11β,16α)-21-(2,2-DiMethyl-1-oxopropoxy)-6,9-difluoro-11,17-dihydroxy-16-Methyl-pregna-1,4-diene-3,20-dione

FluMethasone pivalate USP

Flumetasone pivalate CRS

Flumethasone Pivalate (1274006)

Flumethasone Impurity 13(Flumethasone 21-Pivalate)

Flumethasone pivalate, 10 mM in DMSO

Flumetasone pivalate for ID and assay CRS

2002-29-1

C27H36F2O6

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