TRANS-4-AMINOCYCLOHEXANE CARBOXYLIC ACID ETHYL ESTER
- Product Name
- TRANS-4-AMINOCYCLOHEXANE CARBOXYLIC ACID ETHYL ESTER
- CAS No.
- 1678-68-8
- Chemical Name
- TRANS-4-AMINOCYCLOHEXANE CARBOXYLIC ACID ETHYL ESTER
- Synonyms
- (trans-4-Carboethoxycyclohexyl)amine;Ethyl trans-4-Aminocyclohexanecarboxylate;trans-Ethyl 4-aminocyclohexanecarboxylate;(1s,4s)-ethyl 4-aminocyclohexanecarboxylate;Ethyl trans-4-aminocyclohexane-1-carboxylate;Cyclohexanecarboxylicacid,4-aMino-,ethylester,trans-;TRANS-4-AMINOCYCLOHEXANE CARBOXYLIC ACID ETHYL ESTER
- CBNumber
- CB4767255
- Molecular Formula
- C9H17NO2
- Formula Weight
- 171.24
- MOL File
- 1678-68-8.mol
TRANS-4-AMINOCYCLOHEXANE CARBOXYLIC ACID ETHYL ESTER Property
- Boiling point:
- 139-140℃ (13 Torr)
- Density
- 1.018±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- pka
- 10.36±0.70(Predicted)
- Appearance
- Light yellow to yellow Liquid
N-Bromosuccinimide Price
- Product number
- CHM0068842
- Product name
- ETHYL TRANS-4-AMINOCYCLOHEXANECARBOXYLATE
- Purity
- 95.00%
- Packaging
- 100MG
- Price
- $715.52
- Updated
- 2021/12/16
- Product number
- 9983
- Product name
- Ethyltrans-4-aminocyclohexanecarboxylate
- Packaging
- 100mg
- Price
- $890
- Updated
- 2021/12/16
- Product number
- 9983
- Product name
- Ethyltrans-4-aminocyclohexanecarboxylate
- Packaging
- 0.5g
- Price
- $2120
- Updated
- 2021/12/16
- Product number
- SC-52785
- Product name
- Ethyltrans-4-Aminocyclohexanecarboxylate
- Purity
- 95
- Packaging
- 5g
- Price
- $1767
- Updated
- 2021/12/16
- Product number
- A143828
- Product name
- trans-Ethyl4-aminocyclohexanecarboxylate
- Purity
- 95+%
- Packaging
- 1g
- Price
- $98
- Updated
- 2021/12/16
TRANS-4-AMINOCYCLOHEXANE CARBOXYLIC ACID ETHYL ESTER Chemical Properties,Usage,Production
Chemical Properties
Yellow Solid
Synthesis
64-17-5
27960-59-4
1678-68-8
General procedure for the synthesis of ethyl trans-4-aminocyclohexanecarboxylate from ethanol and trans-4-aminocyclohexanecarboxylic acid hydrochloride: 1. concentrated hydrochloric acid (7 mL) was added to a suspension of (1r,4r)-4-aminocyclohexanecarboxylic acid hydrochloride (6.32 g, 0.035 mol) in ethanol (100 mL) and the mixture was stirred. 2. The mixture was heated to 60 °C and the reaction was kept overnight. 3. Upon completion of the reaction, the mixture was evaporated under vacuum to remove the solvent. 4. The residue was thoroughly removed from water by azeotropy with water, followed by azeotropy with ethanol and finally azeotropy with toluene to afford the title product ethyl trans-4-aminocyclohexanecarboxylate as a white solid (7.2 g, 98% yield). 5. The structure of the product was determined by 1H2O2 analysis. 5. The structure of the product was confirmed by 1H NMR (300 MHz, DMSO-d6): δ 4.05 (q, J = 7.1 Hz, 2H), 2.95 (bs, 1H), 2.30-2.15 (m, 1H), 2.02-1.88 (m, 4H), 1.43-1.28 (m, 4H), 1.22-1.13 (t, J = 6.9 Hz, 3H). Hz, 3H).
References
[1] Patent: WO2016/46390, 2016, A1. Location in patent: Page/Page column 44
[2] Journal of Medicinal Chemistry, 2013, vol. 56, # 22, p. 9199 - 9221
TRANS-4-AMINOCYCLOHEXANE CARBOXYLIC ACID ETHYL ESTER Preparation Products And Raw materials
Raw materials
Preparation Products
TRANS-4-AMINOCYCLOHEXANE CARBOXYLIC ACID ETHYL ESTER Suppliers
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- Country
- Canada
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View Lastest Price from TRANS-4-AMINOCYCLOHEXANE CARBOXYLIC ACID ETHYL ESTER manufacturers
- Product
- TRANS-ETHYL 4-AMINOCYCLOHEXANECARBOXYLATE 1678-68-8
- Price
- US $3.00-9.00/KG
- Min. Order
- 0.1KG
- Purity
- 99%
- Supply Ability
- g-kg-tons, free sample is available
- Release date
- 2025-06-24
- Product
- TRANS-4-AMINOCYCLOHEXANE CARBOXYLIC ACID ETHYL ESTER 1678-68-8
- Price
- US $0.00-0.00/Kg/Drum
- Min. Order
- 1g
- Purity
- 98%
- Supply Ability
- 300kg/month
- Release date
- 2020-12-07