4-PHENOXYPHTHALONITRILE

Product Name: 4-PHENOXYPHTHALONITRILE
CAS No.: 38791-62-7
Chemical Name: 4-PHENOXYPHTHALONITRILE
Synonyms: ROXA-013;NSC 646245;4-PHENOXYPHTHALONITRILE;4-phenoxybenzene-1,2-dinitrile;4-Phenoxy-1,2-benzenedicarbonitrile;RSYY（Cyclobenzaprine hydrochloride)-5;1,2-Benzenedicarbonitrile, 4-phenoxy-
CBNumber: CB4770941
Molecular Formula: C14H8N2O
Formula Weight: 220.23
MOL File: 38791-62-7.mol

More

Less

4-PHENOXYPHTHALONITRILE Property

Melting point:: 98-100 °C(lit.)
Boiling point:: 399.8±37.0 °C(Predicted)
Density: 1.24±0.1 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
form: powder, crystals or chunks
Appearance: Off-white to yellow Solid

More

Less

Safety

Hazard Codes: Xn
Risk Statements: 20/21/22-36/37/38
Safety Statements: 26-36
WGK Germany: 3

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 411930
Product name: 4-Phenoxyphthalonitrile
Purity: 98%
Packaging: 1g
Price: $105.23
Updated: 2025/07/31

Sigma-Aldrich

Product number: 411930
Product name: 4-Phenoxyphthalonitrile
Purity: 98%
Packaging: 5g
Price: $399.9
Updated: 2025/07/31

TRC

Product number: P301600
Product name: 4-Phenoxyphthalonitrile
Packaging: 1g
Price: $140
Updated: 2021/12/16

Usbiological

Product number: 019375
Product name: 4-Phenoxyphthalonitrile
Packaging: 1g
Price: $425
Updated: 2021/12/16

Chem-Impex

Product number: 41873
Product name: 4-Phenoxyphthalonitrile,≥97.5%(GC),suitableforHematology&Histology
Purity: ≥97.5%(GC)
Packaging: 1G
Price: $85.03
Updated: 2021/12/16

More

Less

4-PHENOXYPHTHALONITRILE Chemical Properties,Usage,Production

Uses

4-Phenoxyphthalonitrile is a C4-substituted phthalonitrile with monoamine oxidase inhibitory activity. 4-Phenoxyphthalonitrile is used in organic pigments and dyes. Dyes and metabolites.

Synthesis

31643-49-9

108-95-2

38791-62-7

General procedure for the synthesis of 4-phenoxyphthalonitrile from 4-nitrophthalonitrile and phenol: To a solution of tetrahydrofuran (THF, 15 mL) containing sodium hydride (NaH, 0.15 g) and phenol (0.353 g, 0.0375 mol), slowly add 4-nitrophthalonitrile (0.50 g, 0.0028 mol) to the THF (15 mL ) solution. The reaction mixture was heated to reflux for 8 hours. Upon completion of the reaction, 1,2-diisocyano-4-phenoxybenzene (8) was obtained by filtration and the solid was washed with ethyl acetate. The filtrate and washings were combined and the solvent was removed by evaporation under reduced pressure. The white precipitate obtained was purified by fast column chromatography using ethyl acetate: hexane (1:4) as eluent. The yield was 0.737 g in 86.4% with an Rf value of 0.36 (ethyl acetate: hexane, 1:4).1H NMR (300 MHz, CDCl3) δ 0.90 (s, 2H), 3.46 (m, 5H, CH), 7.07 (m, 3H, ArH).13C NMR (300 MHz, CDCl3) δ 71.01, 117.45, 119.69, 119.92, 126.95, 127.34, 134.43, 135.20.

References

[1] Asian Journal of Chemistry, 2017, vol. 29, # 3, p. 489 - 495
[2] Russian Journal of Organic Chemistry, 2006, vol. 42, # 4, p. 603 - 606
[3] Journal of Photochemistry and Photobiology A: Chemistry, 2010, vol. 209, # 2-3, p. 232 - 237
[4] Bioorganic Chemistry, 2012, vol. 40, # 1, p. 114 - 124
[5] Journal of Organic Chemistry USSR (English Translation), 1992, vol. 28, # 6.2, p. 964 - 967

4-PHENOXYPHTHALONITRILE Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

4-PHENOXYPHTHALONITRILE Suppliers

Canada 1 China 51 France 1 Germany 1 India 2 Japan 1 Switzerland 1 United Kingdom 1 United States 10 Global 69

Alchem Pharmtech,Inc.

Tel: 8485655694
Email: sales@alchempharmtech.com
Country: United States
ProdList: 63687
Advantage: 58

Synthonix Inc

Tel: --
Fax: --
Email: info@synthonix.com
Country: United States
ProdList: 6872
Advantage: 58

Riedel-de Haen AG

Tel: --
Fax: --
Country: United States
ProdList: 6773
Advantage: 87

Alfa Chemistry

Tel: --
Fax: --
Email: info@Alfa-Chemistry.com
Country: United States
ProdList: 6814
Advantage: 0

AsisChem, Inc.

Tel: --
Fax: --
Email: support@asischem.com
Country: United States
ProdList: 4101
Advantage: 55

Reagent World

Tel: --
Fax: --
Email: Sales@ReagentWorld.com
Country: United States
ProdList: 1637
Advantage: 50

Panslavia Chemicals, LLC

Tel: --
Fax: --
Country: United States
ProdList: 310
Advantage: 50

Scientific Exchange

Tel: --
Fax: --
Email: sales@htscompounds.com
Country: United States
ProdList: 404
Advantage: 30

HONEST JOY HOLDINGS LIMITED

Tel: --
Fax: --
Email: sales@honestjoy.cn
Country: United States
ProdList: 6675
Advantage: 54

3B Scientific Corporation

Tel: --
Fax: --
Email: sales@3bsc.com
Country: United States
ProdList: 6718
Advantage: 47

More

Less

View Lastest Price from 4-PHENOXYPHTHALONITRILE manufacturers

Career Henan Chemical Co

Product: 4-PHENOXYPHTHALONITRILE 38791-62-7
Price: US $1.00/KG
Min. Order: 1KG
Purity: 98%
Supply Ability: 100KG
Release date: 2018-08-20

38791-62-7, 4-PHENOXYPHTHALONITRILERelated Search:

Hydroquinone 3-PHENOXYPHTHALONITRILE 4-(1H-1,2,3-benzotriazol-1-yl)-5-phenoxyphthalonitrile 3-PHENOXYPHTHALONITRILE 98,3-PHENOXYPHTHALONITRILE 98% Phthalonitrile 4-METHOXYPHTHALONITRILE 3-Methoxybenzonitrile 3-PHENOXYBENZONITRILE 4-(4-ALPHA-CUMYLPHENOXY)PHTHALONITRILE 4-METHOXY-2-METHYLBENZONITRILE 4-(4-FORMYLPHENOXY)PHTHALONITRILE 4-Hydroxyphthalonitrile 3-Cyanophenol 4-(2',6'-DIMETHYLPHENOXY)PHTHALONITRILE 4-PHENOXYPHTHALONITRILE 4-PHENOXYBENZONITRILE

4-PHENOXYPHTHALONITRILE

4-Phenoxy-1,2-benzenedicarbonitrile

NSC 646245

4-phenoxybenzene-1,2-dinitrile

ROXA-013

1,2-Benzenedicarbonitrile, 4-phenoxy-

RSYY（Cyclobenzaprine hydrochloride)-5

38791-62-7

C14H8ON2

C6H5OC6H312CN2

P

Stains and Dyes

Stains&Dyes, A to