2-Chloro-4,6-dimethoxy-1,3,5-triazine
- Product Name
- 2-Chloro-4,6-dimethoxy-1,3,5-triazine
- CAS No.
- 3140-73-6
- Chemical Name
- 2-Chloro-4,6-dimethoxy-1,3,5-triazine
- Synonyms
- CDMT;AKOS 89995;CDMT 2-Chloro-4,6-diMethoxy-1,3,5-triazine;Chlorodimethoxytriazine;NSC 46520;6-diMethoxy-1;5-triazine (CDMT);2-Chloro-4,6-dimetho;2-Chloro-4,6-dimethoxy-1;2-CHLORO-4,6-DIMETHOXY-TRIAZINE
- CBNumber
- CB4775597
- Molecular Formula
- C5H6ClN3O2
- Formula Weight
- 175.57
- MOL File
- 3140-73-6.mol
2-Chloro-4,6-dimethoxy-1,3,5-triazine Property
- Melting point:
- 71-74 °C (lit.)
- Boiling point:
- 99-100 °C (1 mmHg)
- Density
- 1.7917 (rough estimate)
- vapor pressure
- 5.8Pa at 25℃
- refractive index
- 1.5870 (estimate)
- Flash point:
- 99-100°C/1mm
- storage temp.
- Inert atmosphere,Room Temperature
- solubility
- Chloroform, Methanol
- form
- Crystalline Powder
- pka
- 0.33±0.10(Predicted)
- color
- White to almost white
- Water Solubility
- insoluble
- BRN
- 148988
- InChIKey
- GPIQOFWTZXXOOV-UHFFFAOYSA-N
- LogP
- 2.105 at 25℃
- CAS DataBase Reference
- 3140-73-6(CAS DataBase Reference)
Safety
- Hazard Codes
- Xi
- Risk Statements
- 36/37/38
- Safety Statements
- 26-36/37-36
- RIDADR
- UN3077
- WGK Germany
- 3
- HS Code
- 29339900
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P271Use only outdoors or in a well-ventilated area.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- 375217
- Product name
- 2-Chloro-4,6-dimethoxy-1,3,5-triazine
- Purity
- 97%
- Packaging
- 5g
- Price
- $63.7
- Updated
- 2024/03/01
- Product number
- C1676
- Product name
- 2-Chloro-4,6-dimethoxy-1,3,5-triazine
- Purity
- >97.0%(HPLC)(T)
- Packaging
- 5g
- Price
- $20
- Updated
- 2024/03/01
- Product number
- C1676
- Product name
- 2-Chloro-4,6-dimethoxy-1,3,5-triazine
- Purity
- >97.0%(HPLC)(T)
- Packaging
- 25g
- Price
- $39
- Updated
- 2024/03/01
- Product number
- B24474
- Product name
- 2-Chloro-4,6-dimethoxy-1,3,5-triazine, 98%
- Packaging
- 5g
- Price
- $43.65
- Updated
- 2024/03/01
- Product number
- B24474
- Product name
- 2-Chloro-4,6-dimethoxy-1,3,5-triazine, 98%
- Packaging
- 25g
- Price
- $126
- Updated
- 2024/03/01
2-Chloro-4,6-dimethoxy-1,3,5-triazine Chemical Properties,Usage,Production
Chemical Properties
white to almost white crystalline powder
Uses
2-Chloro-4,6-dimethoxy-1,3,5-triazine is used as a peptide coupling agent for the purification of peptides. It is used in the synthesis of 4-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride through coupling with N-methylmorpholine in tetrahydrofuran. Further, it plays an important role in the production of bis(4,6-dimethoxy-1,3,5-triazin-2-yl) ether, through reaction with 2-hydroxy-4,6-dimethoxy-1,3,5-triazine. In addition to this, it is involved in the preparation of 2-(4,6-dimethoxy-1,3,5-triazinyl)trialkylammonium salts through reaction with various tertiary amines.
Uses
2-Chloro-4,6-dimethoxy-1,3,5-triazine may be used in the following studies:
- The specific labeling of streptavidin by the modular method for affinity labeling (MoAL).
- The preparation of bis(4,6-dimethoxy-1,3,5-triazin-2-yl) ether, via reaction with 2-hydroxy-4,6-dimethoxy-1,3,5-triazine.
- The preparation of 2-(4,6-dimethoxy-1,3,5-triazinyl)trialkylammonium salts, via reaction with various tertiary amines.
- The synthesis of 4-(4,6-dimethoxy-1,3,5-triazin-2-yl)-4-methylmorpholinium chloride, via coupling with N-methylmorpholine in THF.
General Description
2-Chloro-4,6-dimethoxy-1,3,5-triazine is a stable, yet highly reactive, peptide coupling agent. It is reported as useful coupling reagent for the purification of peptides. Catalytic amide-forming reactions of 2-chloro-4,6-dimethoxy-1,3,5-triazine has been reported. Procedure for the preparation of multikilogram quantities of 2-chloro-4,6-dimethoxy-1,3,5-triazine has been reported.
Synthesis
A preparation method of 2-chloro-4,6-dimethoxy-1,3,5-triazine comprises the following steps: using cyanuric chloride and sodium methoxide solid as reaction raw materials and N, N-dimethylformamide as a reaction solvent, gradually heating to obtain a 2-chloro-4,6-dimethoxy-1,3,5-triazine crude product, and finally, recrystallizing with heptane for purification. The reaction temperature is controlled to prepare the product, and the yield is up to 91%.
2-Chloro-4,6-dimethoxy-1,3,5-triazine Preparation Products And Raw materials
Raw materials
Preparation Products
2-Chloro-4,6-dimethoxy-1,3,5-triazine Suppliers
- Tel
- --
- Fax
- --
- yoav@luxembourg-bio.com
- Country
- Israel
- ProdList
- 58
- Advantage
- 58
View Lastest Price from 2-Chloro-4,6-dimethoxy-1,3,5-triazine manufacturers
- Product
- CDMT 2-Chloro-4,6-dimethoxy-1,3,5-triazine 3140-73-6
- Price
- US $0.00-0.00/kg
- Min. Order
- 1kg
- Purity
- 99%
- Supply Ability
- 20MT
- Release date
- 2024-09-26
- Product
- 2-Chloro-4,6-dimethoxy-1,3,5-triazine/CDMT 3140-73-6
- Price
- US $0.00-0.00/Kg/Drum
- Min. Order
- 1KG
- Purity
- 98%min
- Supply Ability
- 1000 KG
- Release date
- 2021-06-03
- Product
- 2-chloro-4,6-dimethoxy-1,3,5-triazine 3140-73-6
- Price
- US $0.00-0.00/Kg
- Min. Order
- 1Kg
- Purity
- 99.9%
- Supply Ability
- 200tons
- Release date
- 2024-04-09