COLIVELIN

Product Name: COLIVELIN
CAS No.: 867021-83-8
Chemical Name: COLIVELIN
Synonyms: COLIVELIN;Colivelin (human);SALLRSIPAPAGASRLLLLTGEIDLP;SER-ALA-LEU-LEU-ARG-SER-ILE-PRO-ALA-PRO-ALA-GLY-ALA-SER-ARG-LEU-LEU-LEU-LEU-THR-GLY-GLU-ILE-ASP-LEU-PRO;H-SER-ALA-LEU-LEU-ARG-SER-ILE-PRO-ALA-PRO-ALA-GLY-ALA-SER-ARG-LEU-LEU-LEU-LEU-THR-GLY-GLU-ILE-ASP-LEU-PRO-OH;Amyloid-β,β-amyloid peptide,STAT,Colivelin,Inhibitor,inhibit,disease,Neuroprotectant,Abeta,ischemic,brain,neurological,alzheimer,injury;Colivelin trifluoroacetate salt H-Ser-Ala-Leu-Leu-Arg-Ser-Ile-Pro-Ala-Pro-Ala-Gly-Ala-Ser-Arg-Leu-Leu-Leu-Leu-Thr-Gly-Glu-Ile-Asp-Leu-Pro-OH trifluoroacetate salt;L-Proline, L-seryl-L-alanyl-L-leucyl-L-leucyl-L-arginyl-L-seryl-L-isoleucyl-L-prolyl-L-alanyl-L-prolyl-L-alanylglycyl-L-alanyl-L-seryl-L-arginyl-L-leucyl-L-leucyl-L-leucyl-L-leucyl-L-threonylglycyl-L-α-glutamyl-L-isoleucyl-L-α-aspartyl-L-leucyl-
CBNumber: CB4795124
Molecular Formula: C119H206N32O35
Formula Weight: 2645.15
MOL File: 867021-83-8.mol

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COLIVELIN Property

Density: 1.42±0.1 g/cm3(Predicted)
storage temp.: Store at -20°C
solubility: insoluble in DMSO; insoluble in EtOH; ≥15 mg/mL in H2O
form: solid
color: White
Water Solubility: Soluble to 1 mg/ml in 20% ethanol / water

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 24239
Product name: Colivelin
Purity: ≥95%
Packaging: 500μg
Price: $242
Updated: 2024/03/01

Cayman Chemical

Product number: 24239
Product name: Colivelin
Purity: ≥95%
Packaging: 1mg
Price: $364
Updated: 2024/03/01

Tocris

Product number: 3945
Product name: Colivelin
Packaging: 500U
Price: $314
Updated: 2021/12/16

TRC

Product number: C641530
Product name: Colivelin
Packaging: 5mg
Price: $2475
Updated: 2021/12/16

Usbiological

Product number: 255021
Product name: Colivelin
Packaging: 500ug
Price: $573
Updated: 2021/12/16

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COLIVELIN Chemical Properties,Usage,Production

Description

Colivelin is a potent synthetic peptide activator of STAT3 that has neuroprotective activity. It protects approximately 50 and 100% of mouse primary cortical neurons from cell death induced by amyloid β (1-43) (Aβ43) when used at concentrations of 10 and 100 fM, respectively. Colivelin protects against cell death induced by V642I-APP in a CaM kinase IV (CaMKIV) and STAT3-dependent manner. It increases STAT3 phosphorylation in vitro and in vivo, an effect that correlates with improvements in working memory. Colivelin (10 pmol every six days) rescues deficits in spatial working memory in a mouse model of Alzheimer’s disease induced by intracerebroventricular injection of Aβ25-35. It also improves motor performance and prolongs survival in a mouse model of amyotrophic lateral sclerosis (ALS).

Uses

Colivelin is a peptide that offers neuroprotective effects against Alzheimer''s Disease (AD). It is also an activator of STAT3, a transcription factor involved with the JAK2/STAT3 pathway. Aberration in this pathway is linked to the pathogenesis of AD. Neuroprotective product.

storage

Store at -20°C

COLIVELIN Preparation Products And Raw materials

Raw materials

Preparation Products

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COLIVELIN Suppliers

China 81 Europe 1 Germany 1 United Kingdom 2 United States 8 Global 93

Cellmano Biotech Limited

Tel: 0551-65326643 18156095617
Fax: 0551-65326641
Email: info@cellmano.com
Country: China
ProdList: 1011
Advantage: 55

3B Pharmachem (Wuhan) International Co.,Ltd.

Tel: 821-50328103-801 18930552037
Fax: 86-21-50328109
Email: 3bsc@sina.com
Country: China
ProdList: 15848
Advantage: 69

GL Biochem (Shanghai) Ltd

Tel: 21-61263452 13641803416
Fax: 86-21-61263399
Email: ymbetter@glbiochem.com
Country: China
ProdList: 9981
Advantage: 64

Chemsky (shanghai) International Co.,Ltd

Tel: 021-50135380
Email: shchemsky@sina.com
Country: China
ProdList: 15421
Advantage: 60

Hangzhou J&H Chemical Co., Ltd.

Tel: +86-571-87396432
Fax: 0571-87396431
Email: sales@jhechem.com
Country: China
ProdList: 10015
Advantage: 53

Creative Peptides

Tel
Email: info@creative-peptides.com
Country: United States
ProdList: 6084
Advantage: 56

ShangHai Biochempartner Co.,Ltd

Tel: 17754423994 17754423994
Fax: QQ:2853530913
Email: 2853530910@QQ.com
Country: China
ProdList: 8003
Advantage: 62

Nanjing Leon Biological Technology Co., Ltd.

Tel: 17705183659
Fax: 84523390
Email: sales@njleonbiotech.com
Country: China
ProdList: 5503
Advantage: 55

Nanjing Peptide Biotech Ltd.

Tel: 025-58361106-805 13082558573
Fax: 025-58361106-806
Email: liugang@njpeptide.com
Country: China
ProdList: 9961
Advantage: 55

Chengdu Youngshe Chemical Co., Ltd.

Tel: 028-62328193 17380623303
Fax: 028-62328193
Email: Caroline@youngshechem.com
Country: China
ProdList: 2353
Advantage: 58

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View Lastest Price from COLIVELIN manufacturers

Hebei Kangcang new material Technology Co., LTD

Product: Colivelin trifluoroacetate salt 867021-83-8
Price: US $20.00-10.00/kg
Min. Order: 1kg
Purity: 98%
Supply Ability: 20
Release date: 2024-04-17

Career Henan Chemical Co

Product: COLIVELIN 867021-83-8
Price: US $1.00/g
Min. Order: 1g
Purity: ≥98%
Supply Ability: g/kg/Ton
Release date: 2020-03-05

867021-83-8, COLIVELINRelated Search:

Tetanus toxin (830-843) PYR-LEU-THR-PHE-THR-SER-SER-TRP-GLY-NH2 PACAP38 NEUROKININ A L-Leu-Leu-Leu COLIVELIN

COLIVELIN

H-SER-ALA-LEU-LEU-ARG-SER-ILE-PRO-ALA-PRO-ALA-GLY-ALA-SER-ARG-LEU-LEU-LEU-LEU-THR-GLY-GLU-ILE-ASP-LEU-PRO-OH

Colivelin (human)

SER-ALA-LEU-LEU-ARG-SER-ILE-PRO-ALA-PRO-ALA-GLY-ALA-SER-ARG-LEU-LEU-LEU-LEU-THR-GLY-GLU-ILE-ASP-LEU-PRO

Colivelin trifluoroacetate salt H-Ser-Ala-Leu-Leu-Arg-Ser-Ile-Pro-Ala-Pro-Ala-Gly-Ala-Ser-Arg-Leu-Leu-Leu-Leu-Thr-Gly-Glu-Ile-Asp-Leu-Pro-OH trifluoroacetate salt

L-Proline, L-seryl-L-alanyl-L-leucyl-L-leucyl-L-arginyl-L-seryl-L-isoleucyl-L-prolyl-L-alanyl-L-prolyl-L-alanylglycyl-L-alanyl-L-seryl-L-arginyl-L-leucyl-L-leucyl-L-leucyl-L-leucyl-L-threonylglycyl-L-α-glutamyl-L-isoleucyl-L-α-aspartyl-L-leucyl-

Amyloid-β,β-amyloid peptide,STAT,Colivelin,Inhibitor,inhibit,disease,Neuroprotectant,Abeta,ischemic,brain,neurological,alzheimer,injury

SALLRSIPAPAGASRLLLLTGEIDLP

867021-83-8

C119H206N32O35

Amyloid beta-peptide and related