Istiratumab

Product Name: Istiratumab
CAS No.: 1509928-04-4
Chemical Name: Istiratumab
Synonyms: Istiratumab;Research Grade Istiratumab;Research Grade Istiratumab (DHC29907)
CBNumber: CB48080936
Formula Weight: 0
MOL File: Mol file

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Istiratumab Property

form: Liquid
color: Colorless to light yellow

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Hazard and Precautionary Statements (GHS)

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Istiratumab Chemical Properties,Usage,Production

Uses

Istiratumab (M-6495) is bispecific monoclonal antibody targeting IGF-1R and ErbB3. Istiratumab induces IGF-1R and ErbB3 receptor degradation through the proteasome pathway Istiratumab can be used for research of cancers[1][2][3].

References

[1] Kundranda M, et al. Randomized, double-blind, placebo-controlled phase II study of istiratumab (MM-141) plus nab-paclitaxel and gemcitabine versus nab-paclitaxel and gemcitabine in front-line metastatic pancreatic cancer (CARRIE). Ann Oncol. 2020 Jan;31(1):79-87. DOI:10.1016/j.annonc.2019.09.004
[2] Camblin AJ, et al. Dual Inhibition of IGF-1R and ErbB3 Enhances the Activity of Gemcitabine and Nab-Paclitaxel in Preclinical Models of Pancreatic Cancer. Clin Cancer Res. 2018 Jun 15;24(12):2873-2885. DOI:10.1158/1078-0432.CCR-17-2262
[3] Camblin AJ, et al. Dual targeting of IGF-1R and ErbB3 as a potential therapeutic regimen for ovarian cancer. Sci Rep. 2019 Nov 14;9(1):16832. DOI:10.1038/s41598-019-53322-y

Istiratumab Preparation Products And Raw materials

Raw materials

Preparation Products

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Istiratumab Suppliers

China 12 Global 12

ShangHai Biochempartner Co.,Ltd

Tel: 177-54423994 17754423994
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Biolab Reagents

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Wuhan Jingkangen Biomedical Technology Co., Ltd

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Email: orders@jknbiochem.com
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Shanghai Yifei Biotechnology Co. , Ltd.

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Shanghai jerryxing Biomedical Technology Co., Ltd

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Changsha Fuzhen Biotechnology Co.，LTD

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Olix (Shanghai) Pharmaceutical Technology Co., Ltd

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Atagenix Laboratories

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AntibodySystem Laboratories SAS

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Country: China
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1509928-04-4, IstiratumabRelated Search:

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Istiratumab

Research Grade Istiratumab (DHC29907)

Research Grade Istiratumab

1509928-04-4