Indatuximab Ravtansine

Product Name: Indatuximab Ravtansine
CAS No.: 1238517-16-2
Chemical Name: Indatuximab Ravtansine
Synonyms: Indatuximab;Indatuximab Ravtansine;Research Grade Indatuximab;Research Grade Indatuximab (DHD30801)
CBNumber: CB28080846
Formula Weight: 0
MOL File: Mol file

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Indatuximab Ravtansine Property

form: Liquid
color: Colorless to light yellow

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Hazard and Precautionary Statements (GHS)

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Indatuximab Ravtansine Chemical Properties,Usage,Production

Uses

Indatuximab ravtansine (BT-062) is an antibody-drug conjugate (ADC) (Antibody-Drug Conjugates (ADCs)) based on a murine/human chimeric form of B-B4 (specific for CD138), linked to the maytansinoid agent DM4 by disulphide bonds. Indatuximab ravtansine shows anti-tumor activities[1].

in vivo

Indatuximab ravtansine (5.3-21.2 mg/kg; i.v.; once) inhibits multiple myeloma tumour growth in vivo and improves host survival^[1].

Animal Model:	SCID mice inoculated with MOLP-8 multiple myeloma xenografts^[1]
Dosage:	5.3 mg/kg, 10.6 mg/kg or 21.2 mg/kg
Administration:	i.v.; once
Result:	Inhibited multiple myeloma tumour growth in vivo and improved host survival.

References

[1] Kurt Sch?nfeld, et al. Indatuximab ravtansine (BT062) combination treatment in multiple myeloma: pre-clinical studies. J Hematol Oncol. 2017 Jan 11;10(1):13. DOI:10.1186/s13045-016-0380-0

Indatuximab Ravtansine Preparation Products And Raw materials

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Preparation Products

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Indatuximab Ravtansine Suppliers

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1238517-16-2, Indatuximab RavtansineRelated Search:

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Indatuximab Ravtansine

Research Grade Indatuximab (DHD30801)

Indatuximab

Research Grade Indatuximab

1238517-16-2