Pamrevlumab

Product Name: Pamrevlumab
CAS No.: 946415-13-0
Chemical Name: Pamrevlumab
Synonyms: FG-3019;Pamrevlumab;Pamrevlumab (anti-CTGF);Research Grade Pamrevlumab;Research Grade Pamrevlumab(DHD82301)
CBNumber: CB48080941
Formula Weight: 0
MOL File: Mol file

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Pamrevlumab Property

form: Liquid
color: Colorless to light yellow

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Hazard and Precautionary Statements (GHS)

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Pamrevlumab Chemical Properties,Usage,Production

Uses

FG-3019 (Pamrevlumab) is a recombinant human antibody that binds to connective tissue growth factor (CTGF). FG-3019 can be used for the research of idiopathic pulmonary fibrosis (IPF)[1][2].

in vivo

FG-3019 (30 mg/kg; i.p. every 3 d for 9 d) in combination with Gemcitabine acutely decreases mouse pancreatic ductal adenocarcinoma (PDA) growth and induces neoplastic cell apoptosis in LSL-Kras^G12D/+;LSL-Trp53^R172H/+;Pdx-1-Cre (KPC) mice^[2].

References

[1] Sgalla G, et, al. Pamrevlumab for the treatment of idiopathic pulmonary fibrosis. Expert Opin Investig Drugs. 2020 Aug;29(8):771-777. DOI:10.1080/13543784.2020.1773790
[2] Neesse A, et, al. CTGF antagonism with mAb FG-3019 enhances chemotherapy response without increasing drug delivery in murine ductal pancreas cancer. Proc Natl Acad Sci U S A. 2013 Jul 23;110(30):12325-30. DOI:10.1073/pnas.1300415110

Pamrevlumab Preparation Products And Raw materials

Raw materials

Preparation Products

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Pamrevlumab Suppliers

CHINA 21 United States 2 Global 23

Shanghai YuanYe Biotechnology Co., Ltd.

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946415-13-0, PamrevlumabRelated Search:

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Pamrevlumab

Research Grade Pamrevlumab(DHD82301)

Research Grade Pamrevlumab

Pamrevlumab (anti-CTGF)

FG-3019

946415-13-0