Pamrevlumab
- Product Name
- Pamrevlumab
- CAS No.
- 946415-13-0
- Chemical Name
- Pamrevlumab
- Synonyms
- FG-3019;Pamrevlumab;Pamrevlumab (anti-CTGF);Research Grade Pamrevlumab;Research Grade Pamrevlumab(DHD82301)
- CBNumber
- CB48080941
- Formula Weight
- 0
- MOL File
- Mol file
Pamrevlumab Property
- form
- Liquid
- color
- Colorless to light yellow
Pamrevlumab Chemical Properties,Usage,Production
Uses
FG-3019 (Pamrevlumab) is a recombinant human antibody that binds to connective tissue growth factor (CTGF). FG-3019 can be used for the research of idiopathic pulmonary fibrosis (IPF)[1][2].
in vivo
FG-3019 (30 mg/kg; i.p. every 3 d for 9 d) in combination with Gemcitabine acutely decreases mouse pancreatic ductal adenocarcinoma (PDA) growth and induces neoplastic cell apoptosis in LSL-KrasG12D/+;LSL-Trp53R172H/+;Pdx-1-Cre (KPC) mice[2].
References
[1] Sgalla G, et, al. Pamrevlumab for the treatment of idiopathic pulmonary fibrosis. Expert Opin Investig Drugs. 2020 Aug;29(8):771-777. DOI:10.1080/13543784.2020.1773790
[2] Neesse A, et, al. CTGF antagonism with mAb FG-3019 enhances chemotherapy response without increasing drug delivery in murine ductal pancreas cancer. Proc Natl Acad Sci U S A. 2013 Jul 23;110(30):12325-30. DOI:10.1073/pnas.1300415110
Pamrevlumab Preparation Products And Raw materials
Raw materials
Preparation Products
Pamrevlumab Suppliers
- Tel
- +1-781-999-5354; +17819995354
- marketing@targetmol.com
- Country
- United States
- ProdList
- 32435
- Advantage
- 58
- Tel
- tp@aladdinsci.com
- Country
- United States
- ProdList
- 57505
- Advantage
- 58