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Olinvacimab

Product Name
Olinvacimab
CAS No.
2095504-49-5
Chemical Name
Olinvacimab
Synonyms
Tanibirumab;Olinvacimab;Olinvacimab (anti-VEGFR2);Research Grade Tanibirumab;Research Grade Olinvacimab;Research Grade Tanibirumab (DHE16604);Research Grade Olinvacimab (DHE16602)
CBNumber
CB48081094
Formula Weight
0
MOL File
Mol file
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Olinvacimab Property

form 
Liquid
color 
Colorless to light yellow
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Hazard and Precautionary Statements (GHS)

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Olinvacimab Chemical Properties,Usage,Production

Uses

Olinvacimab (TTAC-0001) is a fully human anti-VEGFR2 monoclonal antibody. Olinvacimab inhibits VEGF binds to KDR with a Kd value of 0.23 nM. Olinvacimab has antiangiogenic activity. Olinvacimab can be used for the research of recurrent glioblastoma and breast cancer[1].

in vivo

Olinvacimab (100 ng; s.c., once) inhibits angiogenesis in vivo[1].

Animal Model:Matrigel-implanted nude mice model[1]
Dosage:100 ng
Administration:Subcutaneous injection; 100 ng, once
Result:Inhibited the neovascularization induced by hVEGF165.

References

[1] Lee WS, et al. TTAC-0001, a human monoclonal antibody targeting VEGFR-2/KDR, blocks tumor angiogenesis. MAbs. 2015;7(5):957-68. DOI:10.1080/19420862.2015.1045168

Olinvacimab Preparation Products And Raw materials

Raw materials

Preparation Products

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Olinvacimab Suppliers

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2095504-49-5, OlinvacimabRelated Search:


  • Olinvacimab
  • Tanibirumab
  • Research Grade Olinvacimab (DHE16602)
  • Research Grade Tanibirumab (DHE16604)
  • Research Grade Olinvacimab
  • Research Grade Tanibirumab
  • Olinvacimab (anti-VEGFR2)
  • 2095504-49-5