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LDC7559

Product Name
LDC7559
CAS No.
2407782-01-6
Chemical Name
LDC7559
Synonyms
LDC7559;Inhibitor,Pyroptosis,LDC7559,inhibit,LDC 7559,LDC-7559;Acetamide, N-[2-(2-methoxyphenyl)-4H,10H-pyrazolo[5,1-c][1,4]benzoxazepin-7-yl]-;N-(2-(2-Methoxyphenyl)-4,10-dihydrobenzo[f]pyrazolo[5,1-c][1,4]oxazepin-7-yl)acetamide
CBNumber
CB48096799
Molecular Formula
C20H19N3O3
Formula Weight
349.38
MOL File
2407782-01-6.mol
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LDC7559 Property

Boiling point:
596.3±50.0 °C(Predicted)
Density 
1.29±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMSO : ≥ 125 mg/mL (357.78 mM)
pka
14.44±0.20(Predicted)
form 
Solid
color 
White to light yellow
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

ChemScene
Product number
CS-0089815
Product name
LDC7559
Purity
99.64%
Packaging
5mg
Price
$350
Updated
2021/12/16
ChemScene
Product number
CS-0089815
Product name
LDC7559
Purity
99.64%
Packaging
10mg
Price
$550
Updated
2021/12/16
ChemScene
Product number
CS-0089815
Product name
LDC7559
Purity
99.64%
Packaging
50mg
Price
$1650
Updated
2021/12/16
ChemScene
Product number
CS-0089815
Product name
LDC7559
Purity
99.64%
Packaging
100mg
Price
$2300
Updated
2021/12/16
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LDC7559 Chemical Properties,Usage,Production

Description

LDC7559 is a gasdermin D (GSDMD) inhibitor via blocking neutrophil extracellular trap (NET) in the late stages.

in vitro

LDC7559 (1 and 5 μM) inhibits IL-1β release upon inflammasome activation, and significantly blocks the lethal effect of both human and murine GSDMD NT domains transfected into HEK293T cells.
LDC7559 functions directly through blocking the activity of the GSDMD NT domain, rather than interfering with the activation and cleavage process.

LDC7559 Preparation Products And Raw materials

Raw materials

Preparation Products

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LDC7559 Suppliers

TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32161
Advantage
58
TargetMol Chemicals Inc.
Tel
Email
support@targetmol.com
Country
United States
ProdList
38631
Advantage
58
Aladdin Scientific
Tel
+1-+1(833)-552-7181
Email
sales@aladdinsci.com
Country
United States
ProdList
52924
Advantage
58

2407782-01-6, LDC7559Related Search:


  • Acetamide, N-[2-(2-methoxyphenyl)-4H,10H-pyrazolo[5,1-c][1,4]benzoxazepin-7-yl]-
  • LDC7559
  • Inhibitor,Pyroptosis,LDC7559,inhibit,LDC 7559,LDC-7559
  • N-(2-(2-Methoxyphenyl)-4,10-dihydrobenzo[f]pyrazolo[5,1-c][1,4]oxazepin-7-yl)acetamide
  • 2407782-01-6