4-(2-METHOXYETHOXY)ANILINE
- Product Name
- 4-(2-METHOXYETHOXY)ANILINE
- CAS No.
- 33311-29-4
- Chemical Name
- 4-(2-METHOXYETHOXY)ANILINE
- Synonyms
- AKOS BBB/095;AKOS BC-2489;ALINDA 102942;ASISCHEM C40525;CHEMBRDG-BB 4003841;4-(2-Methoxyethoxy);p-Phenetidine, β-methoxy-;4-(2-METHOXYETHOXY)ANILINE;4-(2-methoxyethoxy)phenylamine;4-(2-Methoxyethoxy)-benzenaMine
- CBNumber
- CB4833691
- Molecular Formula
- C9H13NO2
- Formula Weight
- 167.21
- MOL File
- 33311-29-4.mol
4-(2-METHOXYETHOXY)ANILINE Property
- Boiling point:
- 142 °C(Press: 3 Torr)
- Density
- 1.078±0.06 g/cm3(Predicted)
- storage temp.
- under inert gas (nitrogen or Argon) at 2–8 °C
- pka
- 5.10±0.10(Predicted)
- Appearance
- Light brown to brown Solid
- InChI
- InChI=1S/C9H13NO2/c1-11-6-7-12-9-4-2-8(10)3-5-9/h2-5H,6-7,10H2,1H3
- InChIKey
- DIOBEQCFVVJJBU-UHFFFAOYSA-N
- SMILES
- C1(N)=CC=C(OCCOC)C=C1
Safety
- Hazard Codes
- Xi
- HazardClass
- IRRITANT
- HS Code
- 2922290090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P280Wear protective gloves/protective clothing/eye protection/face protection.
N-Bromosuccinimide Price
- Product number
- M304278
- Product name
- 4-(2-Methoxyethoxy)aniline
- Packaging
- 250mg
- Price
- $70
- Updated
- 2021/12/16
- Product number
- 022417
- Product name
- 4-(2-Methoxyethoxy)aniline
- Packaging
- 1g
- Price
- $77
- Updated
- 2021/12/16
- Product number
- Z4603
- Product name
- 4-(2-Methoxyethoxy)aniline
- Packaging
- 250mg
- Price
- $116
- Updated
- 2021/12/16
- Product number
- 022417
- Product name
- 4-(2-Methoxyethoxy)aniline
- Packaging
- 500mg
- Price
- $50
- Updated
- 2021/12/16
- Product number
- Z4603
- Product name
- 4-(2-Methoxyethoxy)aniline
- Packaging
- 10g
- Price
- $537
- Updated
- 2021/12/16
4-(2-METHOXYETHOXY)ANILINE Chemical Properties,Usage,Production
Synthesis
22483-40-5
33311-29-4
General procedure for the synthesis of 4-(2-methoxyethoxy)aniline from 4-nitrophenyl-2-methoxyethyl ether: 1-(2-methoxyethoxy)-4-nitrobenzene (38) (3.9 g, 20 mmol), methanol (80 mL), and 10% activated carbon (400 mg) were added to a hydrogenation reactor. The reaction mixture was stirred overnight at room temperature in a hydrogen atmosphere. Upon completion of the reaction, the mixture was filtered through diatomaceous earth to remove the activated carbon. The filtrate was concentrated in vacuum to afford 4-(2-methoxyethoxy)aniline (39) (3.1 g, 93% yield) as a black oily product. m/z (M+1) 168.1 was shown by LC-MS (ESI) analysis.
References
[1] Bioorganic and Medicinal Chemistry Letters, 2016, vol. 26, # 21, p. 5177 - 5181
[2] Patent: CN103864792, 2017, B. Location in patent: Paragraph 0313; 0314; 0315; 0316
[3] Patent: WO2015/131080, 2015, A1. Location in patent: Paragraph 00768; 00770
[4] Patent: WO2014/130693, 2014, A1. Location in patent: Paragraph 00544; 00547
[5] European Journal of Medicinal Chemistry, 1980, vol. 15, # 5, p. 399 - 404