ChemicalBook > CAS DataBase List > 6-BROMO-1,2,4-TRIAZOLO[4,3-1]PYRIDINE

6-BROMO-1,2,4-TRIAZOLO[4,3-1]PYRIDINE

Product Name
6-BROMO-1,2,4-TRIAZOLO[4,3-1]PYRIDINE
CAS No.
108281-79-4
Chemical Name
6-BROMO-1,2,4-TRIAZOLO[4,3-1]PYRIDINE
Synonyms
6-Bromo[1,2,4]triazolo[4,...;6-BROMO-TRIAZOLO[4,3-A]PYRIDINE;6-BROMO-1,2,4-TRIAZOLO[4,3-1]PYRIDINE;6-BROMO-[1,2,4]TRIAZOLO[4,3-A]PYRIDINE;1,2,4-Triazolo[4,3-a]pyridine, 6-bromo-;6-Bromo-[1,2,4]triazolo[4,3-a]pyridine 98%;6-Bromo-[1,2,4]triazolo[4,3-a]pyridine;6-BROMO-1,2,4-TRIAZOLO[4,3-1]PYRIDINE ISO 9001:2015 REACH
CBNumber
CB4840875
Molecular Formula
C6H4BrN3
Formula Weight
198.02
MOL File
108281-79-4.mol
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6-BROMO-1,2,4-TRIAZOLO[4,3-1]PYRIDINE Property

Melting point:
151-153
Density 
1.89±0.1 g/cm3(Predicted)
storage temp. 
Keep in dark place,Sealed in dry,Room Temperature
pka
2.38±0.50(Predicted)
form 
Solid
Appearance
Light yellow to green yellow Solid
InChI
InChI=1S/C6H4BrN3/c7-5-1-2-6-9-8-4-10(6)3-5/h1-4H
InChIKey
PFKZKSHKBBUZKU-UHFFFAOYSA-N
SMILES
C12=NN=CN1C=C(Br)C=C2
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Safety

Hazard Codes 
Xi,Xn
Risk Statements 
22
WGK Germany 
3
Hazard Note 
Harmful/Irritant/Keep Cold
HS Code 
2933998090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
SYX00142
Product name
6-Bromo-[1,2,4]triazolo[4,3-a]pyridine
Purity
Aldrich
Packaging
1g
Price
$330
Updated
2025/07/31
TRC
Product number
B415498
Product name
6-Bromo-[1,2,4]triazolo[4,3-a]pyridine
Packaging
100mg
Price
$60
Updated
2021/12/16
TRC
Product number
B415498
Product name
6-Bromo-[1,2,4]triazolo[4,3-a]pyridine
Packaging
500mg
Price
$75
Updated
2021/12/16
Apolloscientific
Product number
OR3548
Product name
6-Bromo-[1,2,4]triazolo[4,3-a]pyridine
Purity
98%
Packaging
250mg
Price
$29
Updated
2021/12/16
Frontier Specialty Chemicals
Product number
B12844
Product name
6-Bromo-[1,2,4]triazolo[4,3-a]pyridine
Purity
98%
Packaging
1g
Price
$30
Updated
2021/12/16
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6-BROMO-1,2,4-TRIAZOLO[4,3-1]PYRIDINE Chemical Properties,Usage,Production

Synthesis

77992-44-0

122-51-0

108281-79-4

General procedure for the synthesis of 6-bromo-1,2,4-triazolo[4,3-1]pyridine from 2-hydrazino-5-bromopyridine and triethyl orthoformate: to a solution of 5-bromo-2-hydrazinopyridine (7.87 g, 42 mmol) in 200 mL of diethoxymethoxyethane was added p-toluenesulfonic acid (0.30 g, 1.7 mmol), the mixture was heated to 110 °C and stirred for 20 hours. After completion of the reaction, the mixture was cooled to room temperature and concentrated under vacuum. The residue was diluted with 150 mL of water, washed with saturated aqueous NaHCO3 (40 mL), and extracted with dichloromethane (300 mL × 3). The organic phases were combined, dried with anhydrous Na2SO4, and concentrated under vacuum. Purification of the residue by fast silica gel chromatography (petroleum ether/ethyl acetate, v/v = 2/1) afforded 6-bromo-1,2,4-triazolo[4,3-1]pyridine as a yellow solid (6.60 g, 79.77% yield). Mass spectrum (ESI, cation mode) m/z: 197.9 [M + H]+; 1H NMR (600 MHz, CDCl3): δ 8.82 (s, 1H), 8.34 (s, 1H), 7.75 (d, J = 9.7 Hz, 1H), 7.36 (d, J = 9.7 Hz, 1H).

References

[1] Patent: US2014/134133, 2014, A1. Location in patent: Paragraph 0451

6-BROMO-1,2,4-TRIAZOLO[4,3-1]PYRIDINE Preparation Products And Raw materials

Raw materials

Preparation Products

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6-BROMO-1,2,4-TRIAZOLO[4,3-1]PYRIDINE Suppliers

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View Lastest Price from 6-BROMO-1,2,4-TRIAZOLO[4,3-1]PYRIDINE manufacturers

Dideu Industries Group Limited
Product
6-BROMO-1,2,4-TRIAZOLO[4,3-1]PYRIDINE 108281-79-4
Price
US $1.10/g
Min. Order
1g
Purity
99.00%
Supply Ability
100 Tons Min
Release date
2021-10-28
Career Henan Chemical Co
Product
6-BROMO-1,2,4-TRIAZOLO[4,3-1]PYRIDINE 108281-79-4
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
1ton
Release date
2019-07-10